116 results match your criteria: "Pak Emirates Military Hospital[Affiliation]"
C5aR2 in Breast Cancer and Its Relationship with Clinicopathological Features.
J Coll Physicians Surg Pak
December 2024
Department of Pathology, Army Medical College/Pak. Emirates Military Hospital (PEMH), Rawalpindi, Pakistan.
Objective: To determine the relation between C5aR2 and clinicopathological parameters of breast cancer. Study Design: Observational study. Place and Duration of the Study: Department of Histopathology, PNS Shifa Hospital, Karachi, from January to June 2023.
View Article and Find Full Text PDFCORRELATION OF PRE-TRANSPLANT MELD SCORE WITH 30- AND 60-DAYS' MORTALITY IN PATIENTS OF LIVER TRANSPLANT.
J Ayub Med Coll Abbottabad
December 2024
Hayatabad Medical Complex, Peshawar-Pakistan.
Article Synopsis
- - The MELD score, created in 2002, assesses liver transplant candidates' mortality risk by analyzing kidney, liver, and blood clotting functions, but it doesn't always accurately predict survival for 15-20% of patients.
- - A study conducted from January 2016 to September 2023 with 87 patients found no significant relationship between MELD scores and 30 to 60-day post-transplant survival, suggesting that current methodologies may need reevaluation.
- - The results highlight the importance of considering individual patient factors and advocate for more comprehensive predictive models to improve liver transplantation outcomes through future larger studies.
IMPACT OF HYPOKALEMIA ON HEPATIC ENCEPHALOPATHY AND ITS EFFECT ON DURATION OF STAY IN HOSPITAL.
J Ayub Med Coll Abbottabad
December 2024
PAF Hospital, Islamabad-Pakistan.
Article Synopsis
- Hypokalemia is a key factor in causing hepatic encephalopathy, leading to elevated ammonia levels that can affect the brain.
- A study at PAF Hospital, Islamabad, analyzed the medical records of 179 patients to explore the relationship between hypokalemia and hospital stay duration, using various statistical methods.
- Results indicated that patients with hypokalemia had a significantly longer hospital stay compared to those without it, with an average age of 36.76 years among participants.
CHARACTERIZATION OF CYSTIC PANCREATIC LESIONS ON EUS, A SINGLE CENTRE EXPERIENCE.
J Ayub Med Coll Abbottabad
November 2024
Pakistan Institute of Medical Sciences, Islamabad-Pakistan.
Article Synopsis
- Pancreatic cystic lesions are becoming more common due to improved imaging techniques, necessitating thorough evaluation since some may be cancerous.
- The study analyzed patients with persistent abdominal pain at a military hospital over six months, leading to 88 cystic lesions identified through endoscopic ultrasound (EUS) and further assessment with fine needle aspiration (EUS-FNA).
- Results showed that most patients had a history of pancreatitis, with the majority of lesions located in the pancreatic body, primarily involving pancreatic pseudocysts, and all EUS procedures were successfully completed.
BIOFILLER VS PLATELET-RICH PLASMA MESOTHERAPY IN THE TREATMENT OF PERI-ORBITAL HYPERPIGMENTATION.
J Ayub Med Coll Abbottabad
November 2024
Pak Emirates Military Hospital, Rawalpindi-Pakistan.
Article Synopsis
- Peri orbital hyperpigmentation (POH) is a common skin issue with various causes, and this study aimed to compare the effectiveness of Biofillers vs. Platelet-Rich Plasma (PRP) therapy in treating it.
- In a double-blinded randomized trial involving 42 patients, the results showed that Biofillers provided significant improvements in pigmentation, patient satisfaction, and had fewer side effects compared to PRP.
- The study concluded that Biofillers are a more effective and safer treatment option for POH than PRP therapy.
Outcomes of acetaminophen infusion on visual analogue scale with varying pain intensity during labour, A randomized controlled trial.
Pak J Med Sci
November 2024
Abeera Chaudry, FCPS, FRCS, MRCOG, FRCOG, MCPS-HPE. Professor, Department of Gynaecology and Obstetrics, Pak Emirates Military Hospital, National University of Medical Sciences, Rawalpindi, Pakistan.
Article Synopsis
- - This study evaluated the effectiveness of acetaminophen as an analgesic during labor, comparing its impact on pain reduction against a placebo in a controlled trial format.
- - Conducted on 130 first-time mothers, the trial showed that acetaminophen significantly reduced pain levels after the first dose, but this effect diminished over time after the second dose.
- - The results suggest that acetaminophen can be a useful non-opioid option for managing labor pain, particularly in the early stages of labor.
Determining the Mean Dermatology Life Quality Index of Skin of Color (SOC) Patients With Vitiligo: A South Asian Perspective.
Cureus
October 2024
Dermatology, Academy of Aesthetic Medicine, Shipley, GBR.
Article Synopsis
- Vitiligo significantly impacts the quality of life (QOL) of individuals in the skin of color (SOC) population, leading to lower self-esteem and increased stigma, particularly due to more visible depigmentation.
- A study conducted with 113 vitiligo patients in Pakistan showed a mean Dermatology Life Quality Index (DLQI) score of 9.39, indicating the extent of their challenges.
- Female patients and those with vitiligo universalis reported higher DLQI scores, emphasizing the need for targeted healthcare services for the SOC population affected by this condition.
Association of Androgenetic Alopecia with Metabolic Syndrome.
J Coll Physicians Surg Pak
October 2024
Department of Dermatology, Pak Emirates Military Hospital, Rawalpindi, Pakistan.
Article Synopsis
- * Researchers categorized patients based on clinical assessments of AGA and measured various health parameters, finding significant associations between AGA and factors like Body Mass Index (BMI), fasting blood sugar (FBS), and high-density lipoprotein (HDL).
- * The findings suggested that individuals with AGA have a higher risk of MetS, indicating the need for early screening and lifestyle changes to prevent potential health complications.
Effect of different dialysate temperatures on post dialysis fatigue in patients undergoing haemodialysis: a quasi-experimental study.
J Pak Med Assoc
October 2024
Department of Medicine, Pak Emirates Military Hospital, Rawalpindi, Pakistan.
Article Synopsis
- The study aimed to compare how warm (37°C) and cold (36°C) dialysate solutions affect post-dialysis fatigue in patients on maintenance haemodialysis.
- Conducted at a military hospital in Pakistan, the research involved 92 patients and measured fatigue duration and blood pressure during two different temperature phases.
- Results indicated that the colder dialysate (36°C) led to less frequent and shorter fatigue episodes post-dialysis compared to the warmer solution (37°C).
Anxiety, depression and quality of life in dermatology patients at a tertiary care hospital.
J Pak Med Assoc
October 2024
Pak Emirates Military Hospital, Rawalpindi, Pakistan.
Article Synopsis
- - This study aimed to compare anxiety, depression, and health-related quality of life between dermatology patients and healthy individuals at a hospital in Pakistan.
- - Researchers conducted a case-control study with 200 subjects, evenly split between patients with skin diseases (Group A) and healthy individuals (Group B), using questionnaires to gather data on their mental health and quality of life.
- - Results showed that dermatological conditions significantly affected the psychological health and daily life of patients, indicating higher anxiety and depression scores compared to the healthy control group.
Sanger Sequencing Reveals Novel Variants in , , and Genes in Patients of Early and Severe Diabetic Nephropathy.
Medicina (Kaunas)
September 2024
Pak Emirates Military Hospital, Rawalpindi 46000, Pakistan.
Article Synopsis
- Diabetes is a serious health problem worldwide, with many patients developing kidney issues called diabetic nephropathy (DN) quickly after being diagnosed.
- Researchers studied the genes of 113 patients with severe DN to see how genetic changes might cause the disease to get worse faster.
- They found several important genetic mutations that could affect how some proteins work, possibly making DN progress more rapidly in these patients.
Waardenburg Syndrome: A Rare Disorder with an Uncommon Manifestation in a Neonate.
J Coll Physicians Surg Pak
September 2024
Department of Paediatrics, Pak Emirates Military Hospital, Rawalpindi, Pakistan.
Article Synopsis
- Null refers to the absence of a value or a non-existent object in programming and databases.
- It is often used to signify that a variable has not been initialized or that a data entry is empty.
- Understanding null is crucial for avoiding errors and ensuring proper data handling in software development.
Comparison Between Pregabalin and Sertraline for Treatment of Uraemic Pruritus in Patients on Maintenance Haemodialysis: A Single-Centric Study.
J Coll Physicians Surg Pak
September 2024
Department of Medicine, Pak Emirates Military Hospital, Rawalpindi, Pakistan.
Article Synopsis
- The study aimed to compare the effectiveness of oral pregabalin and oral sertraline for treating uraemic pruritus in patients with end-stage renal disease.
- Conducted as a randomized controlled trial at a military hospital in Pakistan between October 2023 and January 2024, patients were assigned either pregabalin at 75mg or sertraline at 50mg daily for six weeks.
- Results showed that pregabalin significantly improved itch severity more than sertraline, although a few side effects were noted in the pregabalin group with no side effects reported in the sertraline group.
Outcomes of robotic versus laparoscopic-assisted surgery in patients with rectal cancer: a systematic review and meta-analysis.
Langenbecks Arch Surg
September 2024
Department of medicine, King Edward Medical University, Lahore, Pakistan.
Article Synopsis
- The meta-analysis compares robotic-assisted rectal surgery (RARS) and laparoscopic-assisted rectal surgery for treating rectal cancer, evaluating their advantages, disadvantages, and outcomes.
- RARS demonstrated a lower conversion rate to open surgery and a reduced reoperation rate compared to laparoscopic surgery, with no significant differences in most postoperative complications.
- The findings suggest that RARS may be safer and more effective, though larger, high-quality studies are needed to confirm these results.
Collaboration cognizance: Development of a self-assessment tool to measure intra-professional collaborative practices (IPCP) in postgraduate medical residents at tertiary care hospitals.
BMC Med Educ
July 2024
Dean Riphah Institute of Assessment, Riphah International University, Islamabad, Pakistan.
Article Synopsis
- The study focuses on the need for improved intraprofessional collaboration among postgraduate residents in healthcare settings, aiming to create a reliable tool for assessing these collaborative practices in multidisciplinary teams.* -
- Using a mixed-method approach, the research identified six key domains of collaboration and gathered expert feedback to refine a 35-item instrument, ensuring content validity through multiple rounds of evaluation.* -
- The validation process included cognitive interviews and pilot testing with over 400 residents, revealing that most items successfully met the Content Validity Index criteria, establishing the tool's effectiveness for ongoing assessment in residency programs.*
Improvement in Inhaler Techniques After Training and Counseling in Patients With Chronic Obstructive Pulmonary Disease or Asthma.
Cureus
June 2024
Psychiatry and Behavioral Sciences, Lahore General Hospital, Lahore, PAK.
Article Synopsis
- Chronic respiratory diseases like COPD and asthma impact quality of life and healthcare systems, with proper inhaler technique being crucial for effective management, yet frequently inadequately performed by patients.
- This study involved 150 patients and evaluated the effectiveness of structured counseling and training on correct inhaler use, specifically focusing on metered-dose inhalers (MDI), MDIs with spacers, and dry powder inhalers (DPI).
- Results showed significant improvements in inhaler technique and disease control after three months, with enhanced technique scores and decreased COPD Assessment Test (CAT) scores, indicating better management of symptoms.
Comparison of Efficacy of Autologous Platelet Rich Plasma Therapy With 5% Topical Minoxidil Spray in Treating Alopecia Areata: A Head-to-Head Assessment of Novel Approaches.
Cureus
June 2024
Internal Medicine, Pakistan Ordnance Factory (POF) Hospital, Islamabad, PAK.
Article Synopsis
- Alopecia areata (AA) is a difficult autoimmune condition causing non-scarring hair loss, and researchers are comparing the effectiveness of autologous platelet-rich plasma (PRP) therapy and topical minoxidil as treatment options.
- A study involving 40 patients over four months evaluated the two treatments, with one group receiving monthly PRP injections and the other using daily minoxidil spray, measuring hair loss severity with the Severity of Alopecia Tool (SALT) scoring system.
- Results showed no significant difference between the treatments after one month, but by the two-month mark, PRP therapy demonstrated a statistically significant greater improvement in SALT scores compared to minoxidil (p-value 0.037).
Thrombocytopenia and Grading of Esophageal Varices in Patients With Chronic Liver Disease.
Cureus
May 2024
Psychiatry and Behavioral Sciences, Lahore General Hospital, Lahore, PAK.
Article Synopsis
- * A study of 94 patients with CLD found significant differences in platelet counts across varying grades of esophageal varices, with lower platelet counts associated with more severe varices.
- * The results indicated a negative correlation between platelet counts and the severity of esophageal varices, suggesting that monitoring platelet levels could help assess risk in CLD patients.
Comparison of oxidative stress, lipid peroxidation and inflammatory markers between rheumatoid arthritis and ankylosing spondylitis patients.
J Pak Med Assoc
May 2024
Department of Biochemistry and Molecular Biology, Army Medical College, Rawalpindi, Pakistan.
Article Synopsis
- The study aimed to measure specific biomarkers (superoxide dismutase, malondialdehyde, erythrocyte sedimentation rate, and C-reactive protein) in patients with rheumatoid arthritis and ankylosing spondylitis, compared to healthy controls.
- Conducted from February to December 2022 in Pakistan, the study included 180 subjects divided into three groups: healthy controls, rheumatoid arthritis patients, and ankylosing spondylitis patients, with blood samples analyzed using SPSS 25 for data assessment.
- Results showed lower superoxide dismutase and higher malondialdehyde levels in the patient groups, indicating oxidative stress's significant role in these chronic inflammatory diseases.
Comparison of Endoscopic Ultrasound and Transabdominal Ultrasound in the Detection of Gallbladder and Common Bile Duct Microlithiasis.
Cureus
April 2024
Basic Sciences, Brown University, Providence, USA.
Article Synopsis
- Endoscopic ultrasonography (EUS) is being evaluated as an effective method for diagnosing conditions related to the gallbladder and bile duct, especially in cases where initial transabdominal ultrasound (TUS) results are normal.
- In a study involving 131 patients with biliary colic, EUS showed high sensitivity (92.9% for CBD stones and 98.8% for gallbladder microlithiasis) and specificity (100% for both) compared to TUS, which had much weaker agreement.
- The results indicate that EUS is a more reliable diagnostic tool than TUS for detecting gallstones and microlithiasis, though the study's findings are limited by being conducted at a single
Comparative Efficacy of Intralesional Chloroquine With Intralesional Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis.
Cureus
March 2024
Department of Dermatology, Sandeman Provincial Hospital, Quetta, PAK.
Article Synopsis
- - This study was conducted at a military hospital in Pakistan to compare the effectiveness of two treatments, intralesional chloroquine and intralesional meglumine antimoniate, for cutaneous leishmaniasis, over a six-month period.
- - A total of 64 patients were divided into two groups, with one group receiving chloroquine and the other receiving meglumine antimoniate, both treated twice a week and evaluated after eight weeks.
- - Results showed that 53.1% of patients treated with meglumine antimoniate achieved efficacy, compared to only 18.8% in the chloroquine group, indicating a statistically significant difference favoring meglumine antimoniate as the more effective treatment.
Therapeutic efficacy and drug safety comparison of one-week Vonoprazan triple therapy with two-weeks Esomeprazole triple therapy in Helicobacter pylori infection: Findings from a single-centre randomized clinical trial in population of Pakistan.
J Pak Med Assoc
March 2024
Department of Pharmacology, Army Medical College, Rawalpindi, Pakistan.
Article Synopsis
- - The study aimed to compare the effectiveness and safety of two triple therapies for treating Helicobacter pylori: a 2-week Esomeprazole regimen and a 1-week Vonoprazan regimen, conducted at a medical college in Pakistan.
- - Out of 122 participants, the Vonoprazan group had a higher eradication rate (95%) compared to Esomeprazole (93.4%) and reported fewer adverse effects like nausea and abdominal pain.
- - The conclusion indicates that Vonoprazan may be a better option for treatment because it is more effective and has a shorter duration, leading to better patient adherence.
National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma.
World J Gastroenterol
March 2024
Department of Gastroenterology & Hepatology, Pakistan Kidney and Liver Institute & Research Centre, Lahore 54000, Pakistan.
Article Synopsis
- A consensus meeting of national hepatobiliary experts took place on May 26, 2023, at PKLI & RC, aiming to develop guidelines for managing hilar cholangiocarcinoma (hCCA).
- The meeting emphasized the need for a multidisciplinary approach to manage hCCA effectively, highlighting diagnostic methods like CT and MRI for staging, as well as the importance of surgical resection for potentially curative treatment.
- For patients with unresectable hCCA, options include liver transplantation and palliative chemotherapy, with guidelines suggesting personalized treatment plans based on local discussions.
Comparing the Efficacy of Topical 4% Benzoyl Peroxide Versus Topical 0.1% Adapalene for Treatment of Acne Vulgaris in Skin of Color Population: A South Asian Perspective.
Cureus
March 2024
Dermatology, Pak-Emirates Military Hospital, Rawalpindi, PAK.
Article Synopsis
- Acne vulgaris is a chronic skin condition characterized by various forms of acne such as comedones and pustules, which significantly impacts the quality of life, especially among younger individuals.
- Current treatment strategies involve a systematic approach that adapts to the severity of the acne, with topical agents like retinoids and benzoyl peroxide preferred for mild to moderate cases, while oral options are reserved for more severe conditions.
- This study aims to compare the effectiveness of topical 4% benzoyl peroxide and 0.1% adapalene for treating acne vulgaris in patients with skin of color, emphasizing the need for more tailored treatment options in this neglected population.
Clinical Spectrum of Hereditary Tyrosinemia Type 1 in a Cohort of Pakistani Children.
Clin Med Insights Pediatr
March 2024
Shifa College of Medicine, Tameer-e-Millat University, Islamabad, Pakistan.
Article Synopsis
- Hereditary Tyrosinemia Type 1 (HT1) is a rare genetic disorder caused by a deficiency of the FAH enzyme, leading to the buildup of harmful metabolites that can present in various forms, making early diagnosis and treatment crucial.
- A study conducted on Pakistani children with HT1 showed an average presentation age of 8 months and a significant delay in diagnosis, with a majority of the patients suffering from liver disease and other complications such as rickets.
- The findings highlight that delayed referrals and lack of access to Nitisinone treatment are significant barriers to effective management of HT1 in Pakistan, resulting in a high mortality rate among patients.