Zirconium-doped iron oxide nanoparticles for enhanced peroxidase-like activity.

FeO nanoparticles (NPs) have emerged as pioneering nanozymes with applications in clinical diagnosis, environmental protection and biosensing. However, it is currently limited by insufficient catalytic activity due to poor electron transfer. In this study, we synthesized electron-rich-Zr-doped defect-rich FeO NPs (ZrFeO) using a one-pot solvothermal method.

Antibiotic resistance gene pollution in poultry farming environments and approaches for mitigation: A system review.

Antibiotic resistance genes (ARG) pollution in poultry farming environments has become increasingly critical, primarily driven by the widespread use of antibiotics in animal husbandry. Prolonged antibiotic use has led to the emergence of ARGs and antibiotic-resistant bacteria, spreading via horizontal and vertical gene transfer. The complexity of ARG pollution in poultry farming arises from the unique farming practices, physiological characteristics of poultry, and manure management methods, with manure, wastewater, and air serving as significant vectors for ARG dissemination.

Molecular characteristics of avian leukosis viruses isolated from indigenous chicken breeds in Yunnan Province, Southwestern China.

Indigenous chicken breeds have a large market share in China due to their superior production traits, including high meat quality and disease resistance. Yunnan Province is recognized as a major source of domestic chickens globally and boasts a diverse array of indigenous chicken resources. Avian leukosis virus (ALV) induces various tumors and immunosuppression, endangering the poultry industry.

Goose multi-omics database: A comprehensive multi-omics database for goose genomics.

Multi-omics has helped elucidate the gene expression patterns and genomic variations closely associated with economically significant traits in geese. Despite the substantial genomic data generated through extensive goose studies, a unified platform for integrating these datasets is lacking. To address this gap, we introduced the Goose Multi-omics Database (GMD), which is accessible at http://goosedb.

A particle counting immunosensor for the sensitive detection of ochratoxin A via click chemistry-mediated signal amplification.

The existence of ochratoxin A (OTA) in agricultural products poses significant threats to human health and environment, underscoring the critical need for its prompt and precise quantification. A particle counting immunosensor for the highly sensitive detection of OTA was presented, employing SiO@CuO nanoparticles to facilitate click chemistry. The quantity of SiO@CuO nanoparticles, and consequently the Cu²⁺ concentration, can be directly altered through the immune response involving OTA.

Carnivorous fishes can possess higher mercury levels than omnivorous fishes: A selective detection and efficient removal strategy for mercury using magnetic melamine-platinum composites fabricated by supermolecular self-assembly.

Mercury (II) ion (Hg) as highly toxic heavy metal may be accumulated in aquatic ecosystems and animals species so as to enter human body to conduct health harm. To ensure the safety of fishes food, hence, it is of great interest to evaluate the Hg levels in different kinds of fishes as well as Hg removal in aquaculture tailwater. In this article, a selective colormetric detection and efficient removal strategy has been developed for Hg ions by the controlled supermolecular self-assembly of melamine (MA)-platinum (Pt) composites onto mesoporous FeO carriers.

Bacterial activation level determines Cd(II) immobilization efficiency by calcium-phosphate minerals in soil.

Soil mineral properties significantly influence the mobility of Cd(II) within the soil matrix. However, the limited understanding of how microbial metabolism affects mineral structure at the microscale poses challenges for in situ remediation. Here, we designed a model calcium-phosphate system in a urea-rich environment to explore the impact of different microbial activation levels on Cd(II) fixation at mineral interfaces.

Organic acid release and microbial community assembly driven by phosphate-solubilizing bacteria enhance Pb, Cd, and As immobilization in soils remediated with iron-doped hydroxyapatite.

Although iron-doped hydroxyapatite (Fe-HAP) and its composites have been reported to immobilize arsenic (As), lead (Pb), and cadmium (Cd), its practical application is limited by the inefficient release of iron and phosphate. In this study, Ochrobactrum anthropic, a phosphate-solubilizing bacterium isolated from a lead-zinc smelting site, was employed to enhance multi-heavy metal immobilization in Fe-HAP-amended soils. O.

The inhibition of anammox system under Cu stress and mechanisms of biochar-mediated recovery.

Copper (Cu)-containing wastewater has proven difficult to effectively treat using the anammox process. In this study, the nitrogen removal efficiency (NRE), sludge characteristics, microbial community and recovery mechanisms of biochar-mediated anammox under Cu stress were elucidated. At a Custress of 5 mg/L, a 73.

Hemodynamic investigations on the portal hypertension and treatment of transjugular intrahepatic portosystemic shunt (TIPS) based on CFD simulation.

Hemodynamic processes from the portal vein(PV) to the inferior vena cava(IVC) were mimicked for three patients with portal hypertension(PH) and the effects of stent parameters on the outcomes of transjugular intrahepatic portosystemic shunt(TIPS) were investigated through computational fluid dynamics(CFD). The liver region was simulated with porous media model and the spatial distributions of superior mesenteric vein(SMV) and splenic vein(SV) blood were solved through the Eulerian multiphase model. The present method is able to simulate the PH flow and predict the PV pressure, the stent shunt rate and the SMV blood proportion after TIPS treatment.

Comprehensive comparison on different wavelength selection methods using several near-infrared spectral datasets with different dimensionalities.

NIR spectroscopy is widely used in chemical analysis, agricultural science, food safety, and other fields, but its high dimensionality and data redundancy bring analytical challenges. This study aims to compare the performance of different wavelength selection methods in NIR spectral datasets with different dimensionalities to provide a reference for researchers. The wavelength selection methods in this study were classified into four categories according to their principles, which are partial least squares (PLS) parameter-based methods, intelligent optimization algorithms (IOA)-based methods, model population analysis (MPA)-based methods and wavelength interval selection (WIS) methods.

The effects of Fraxini cortex and Andrographis herba on Escherichia coli-induced diarrhea in chicken.

Escherichia coli (E. coli) is a type of pathogenic bacteria that often causes diarrhea in poultry. While antibiotics can control E.

Synthesis and characteristics of type 3 resistant waxy corn starch by removal of starch granule surface proteins and heat-moisture treatment.

The type 3 resistant waxy corn starch (RS3) was synthesized by removing starch granule surface proteins and subjecting it to heat-moisture treatment at -20°C, 4°C, and 25°C. Upon applying the dual modification, a significant reduction in particle size and in vitro digestion was observed, while the gelatinization enthalpy, relative crystallinity, and resistant starch content increased. Notably, RS3 treated at 4°C demonstrated the lowest digestion rate of 3.

Electrolyte reactivity on electrode surfaces for active species formation and Reactive Red X-3B degradation in electrochemical treatment of dyeing wastewater.

The pivotal role of electrolytes such as NaSO and NaCl in electrochemical treatment of dyeing wastewater was investigated by comparing recalcitrant Reactive Red X-3B (RRX-3B) degradation rates, active species formation and intermediates generation in a double-chamber cell. It was found that similar reactive oxygen species (ROS) formed in the anodic chamber are OH and O, in the cathodic chamber is O with different electrolytes, while this is not the case for ROS contribution, RRX-3B degradation kinetic and intermediates. NaCl favored the generation of O, faster decolorization (-N=N- cleavage), and organic intermediates degradation in the anodic chamber.

Electromagnetism and thermostability of CrCsynthesised with high-temperature and high-pressure quenching method.

The interactions between the carbon skeleton and the metal atoms of a binary transition metal carbide (BTMC) are particular interest for industrial applications with openning physics and chemitry questions, especially in magnetoelectric (ME) functional materials and cemented carbides. Chromium and carbon BTMCs are a series of intermetallic compounds with typical chemical formulas and sharepolycrystalline powder c somehromium special characteristics.and carbon as precursors, In this paper,and synthesized s we usedingle-phase bluk Cr7C3 (orthorhombic, with space group: Pnma) with high density and good crystallinity by means of high-temperature and high-pressure quenching method (HTHPQM).

Dual oxygen supply system of carbon dot-loaded microbubbles with acoustic cavitation for enhanced sonodynamic therapy in diabetic wound healing.

Diabetic wounds present significant treatment challenges due to their complex microenvironment, marked by persistent inflammation from bacterial infections, hypoxia caused by diabetic microangiopathy, and biofilm colonization. Sonodynamic therapy (SDT) offers potential for treating such wounds by targeting deep tissues with antibacterial effects, but its efficacy is limited by hypoxic conditions and biofilm barriers. To overcome these obstacles, we developed a novel approach using oxygen-carrying microbubbles loaded with Mn-doped carbon dots (MnCDs@OMBs) to enhance SDT and disrupt biofilms.

Two multifunctional zero-dimensional Gd(III) complexes: magnetocaloric effect and anticancer mechanisms for lung cancer.

Two Gd(III) complexes [GdL(HO)(NO)(CHOH)(CHCHOH)] (Gd1) and [Gd(OOCCH)L(HO)]•2(HO) (Gd2) (HL = 2-pyridylcarboxaldehyde isonicotinoylhydrazone) were synthesized with a Schiff base ligand. Crystallographic study reveals both Gd1 and Gd2 have a zero-dimensional mononuclear or binuclear structure. Magnetic investigations demonstrate that Gd1 and Gd2 exhibit potential magnetocaloric effects due to Gd(III) ions, which provide negligible magnetic anisotropy, and possess low-lying excited spin states.

How far do we still need to go with antibiotics in aquatic environments? Antibiotic occurrence, chemical-free or chemical-limited strategies, key challenges, and future perspectives.

Global consumption and progressive migration of antibiotics through aquatic systems have contributed to their rapid spread, posing significant threats to environmental and human health, and antibiotics have been recognized as emerging pollutants. Hence, extensive approaches have been proposed for antibiotic treatment in water, yielding great achievements. This review systematically summarized current knowledge from contamination characteristics to treatment strategies.

Cystine-Modified Lignin-Copper Coordination Nanocarriers Improve the Therapeutic Efficacy of Tyrosine Kinase Inhibition via Cuproptosis.

The clinical application of tyrosine kinase inhibitors (TKIs) is rapidly growing and has emerged as a cornerstone in the treatment of both solid tumors and hematologic malignancies. However, resistance to TKI targets and disease progression remain inevitable. Nanocarrier-mediated delivery has emerged as a promising strategy to overcome the limitations of the TKI application.

Dapagliflozin inhibits ferroptosis to improve chronic heart failure by regulating Nrf2/HO-1/GPX4 signaling pathway.

Objective: To study the effect of Dapagliflozin on ferroptosis in rabbits with chronic heart failure and to reveal its possible mechanism.

Methods: Nine healthy adult male New Zealand white rabbits were randomly divided into Sham group (only thorax opening was performed in Sham group, no ascending aorta circumferential ligation was performed), Heart failure group (HF group, ascending aorta circumferential ligation was performed in HF group to establish the animal model of heart failure), and Dapagliflozin group (DAPA group, after the rabbit chronic heart failure model was successfully made in DAPA group). Dapagliflozin was given by force-feeding method.

Spatial Scale Matters: Hydrolysis of Aryl Methyl Ethers over Zeolites.

The local environment of the active site, such as the confinement of hydronium ions within zeolite pores, significantly influences catalytic turnover, similar to enzyme functionality. This study explores these effects in the hydrolysis of guaiacols─lignin-derived compounds─over zeolites in water. In addition to the interesting catechol products, this reaction is advantageous for study due to its bimolecular hydrolysis pathway, which involves a single energy barrier and no intermediates, simplifying kinetic studies and result interpretation.

QUEST#4X: An Extension of QUEST#4 for Benchmarking Multireference Wave Function Methods.

Given a number of data sets for evaluating the performance of single reference methods for the low-lying excited states of closed-shell molecules, a comprehensive data set for assessing the performance of multireference methods for the low-lying excited states of open-shell systems is still lacking. For this reason, we propose an extension (QUEST#4X) of the radical subset of QUEST#4 ( , , 3720) to cover 110 doublet and 39 quartet excited states. Near-exact results obtained by iterative configuration interaction with selection and second-order perturbation correction (iCIPT2) are taken as benchmark to calibrate static-dynamic-static configuration interaction (SDSCI) and static-dynamic-static second-order perturbation theory (SDSPT2), which are minimal MRCI and CI-like perturbation theory, respectively.

Inhibition of mitochondrial energy production leads to reorganization of the plant endomembrane system.

Mitochondria have generated the bulk of ATP to fuel cellular activities, including membrane trafficking, since the beginning of eukaryogenesis. How inhibition of mitochondrial energy production will affect the form and function of the endomembrane system and whether such changes are specific in today's cells remain unclear. Here, we treated Arabidopsis thaliana with antimycin A (AA), a potent inhibitor of the mitochondrial electron transport chain (mETC), as well as other mETC inhibitors and an uncoupler.

Body mass index, regional adipose deposition, and clinical outcomes in non-ischemic dilated cardiomyopathy: a prospective cohort study.

Aim: To assess the relationship between body mass index (BMI), subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT), epicardial adipose tissue (EAT), pericardial adipose tissue (PAT) and clinical outcomes in dilated cardiomyopathy (DCM) patients.

Methods: Non-ischemic DCM patients were prospectively enrolled. Regional adipose tissue, cardiac function, and myocardial tissue characteristics were measured by cardiac magnetic resonance (CMR).

High-Conductivity, Self-Healing, and Adhesive Ionic Hydrogels for Health Monitoring and Human-Machine Interactions Under Extreme Cold Conditions.

Ionic conductive hydrogels (ICHs) are emerging as key materials for advanced human-machine interactions and health monitoring systems due to their unique combination of flexibility, biocompatibility, and electrical conductivity. However, a major challenge remains in developing ICHs that simultaneously exhibit high ionic conductivity, self-healing, and strong adhesion, particularly under extreme low-temperature conditions. In this study, a novel ICH composed of sulfobetaine methacrylate, methacrylic acid, TEMPO-oxidized cellulose nanofibers, sodium alginate, and lithium chloride is presented.