Spray drying of reconstituted skim milk fermented with GG: control of glass transition and stickiness.

The effects of glass transition and stickiness on the direct spray drying of reconstituted skim milk (RSM) fermented with GG (LGG) were investigated. The fermented RSM did not spray dry properly due to severe wall depositions; however, it dried well (comparable to the control; RSM with resuspended LGG cells) when skim milk powder (SMP) was added. Adding SMP significantly increased the glass transition and sticky point temperatures of spray-dried powder, ranging from 18.

Study on Carbon Dioxide Capture Using Ternary Betaine-Based Deep Eutectic Solvents.

The application of existing ternary betaine (Be)-based deep eutectic solvents (DESs) faces inevitable limitations due to the low regenerability and water absorption capability of the DESs. In this study, three ternary Be-based DESs with different molar ratios were prepared by adding the promoter diethanolamine (DEA) to the binary system of Be and ethylene glycol (EG). The effects of DEA, temperature, and flow rate on CO absorption by the Be-based DESs were then investigated.

Ferrocenyl-Substituted Curcumin Derivatives as Potential SHP-2 Inhibitors for Anticolorectal Cancer: Design, Synthesis and Evaluation.

A panel of ferrocenyl-substituted curcumin derivatives has been designed and synthesized as protein tyrosine phosphatase proto-oncogene SHP-2 inhibitors. Antiproliferative activities of the synthesized compounds were tested against colorectal cancer cell lines (including RKO, SW480, and CT26). Compound showed excellent activities against the tested cell lines with IC values of 5.

Effect of Ar on Temperature and Flow Distribution in Monocrystalline Graphene Growth: Inert Gas Is Active.

Monocrystalline graphene growth has always been an intriguing research focus. Argon (Ar) is merely viewed as a carrier gas due to its inert chemical properties throughout the whole growth procedure by the chemical vapor deposition method. In this work, the influence of Ar on temperature and flow fields was investigated in consideration of its physical parameter difference among all involved gases.

Synthesis of 2,7-Dihydrooxepine-spirodithiophene Derivatives via an Intramolecular Ring Closure Reaction.

Spiro architectures with π-conjugation have improved thermal stability and stronger photosensitivity, making them potentially useful for organic optoelectronic devices. Our recent work has demonstrated the synthetic chemistry of a novel thiophene oligomer combining 2,7-dihydrooxepine and dispiro structure and derived it into A-D-A-type compounds. The optical spectroscopy and electrochemical characteristics were investigated.

Study of the Pore Structure and Fractal Characteristics of the Leping Formation Shale in the Junlian Block, Southern Sichuan Basin.

The pore structure of shale is a key factor affecting the occurrence and flow of shale gas, and fractal dimensions can be used to quantitatively describe the complexity of the shale pore structure. In this study, the Leping Formation shale in the Junlian block of the southern Sichuan Basin was investigated. The pore structure characteristics of this shale were examined via low-pressure CO adsorption (LP-COA) and low-temperature N adsorption (LT-NA) methods via field emission scanning electron microscopy (FE-SEM), shale geochemistry, and mineral composition analysis.

Molding Quality and Biological Evaluation of a Two-Stage Titanium Alloy Dental Implant Based on Combined 3D Printing and Subtracting Manufacturing.

Metal 3D printing has been used in the manufacturing of dental implants. Its technical advantages include high material utilization and the capacity to form arbitrarily complex structures. However, 3D printing alone is insufficient for manufacturing two-stage titanium implants due to the limited precision in printing titanium alloy parts.

Low expression of TOX predicts poor prognosis of patients with breast cancer in the real world: A retrospective study.

Background: TOX is a transcription factor that is implicated in the regulation of T cell exhaustion in tumors. TOX has been proven to have prognostic value in some malignant tumors. We aim to analyze the expression of TOX in breast cancer patients, and the association between TOX and prognostic significance in patients with breast cancer.

The impact of small food workshops management regulations on aflatoxin B in home-made peanut oil and the liver function of high-consumption area residents: an interrupted time series study in Guangzhou, China.

Background: Aflatoxin B (AFB), a potent carcinogen produced by species, is a prevalent contaminant in oil crops, with prolonged exposure associated with liver damage. Home-made peanut oil (HMPO) produced by small workshops in Guangzhou is heavily contaminated with AFB. Despite the enactment of the Small Food Workshops Management Regulations (SFWMR), no quantitative assessment has been conducted regarding its impact on food contamination and public health.

Regulatory significance of terminator: A systematic approach for dissecting terminator-mediated enhancement of upstream mRNA stability.

The primary function of terminators is to terminate transcription in gene expression. Although some studies have suggested that terminators also contribute positively to upstream gene expression, the extent and underlying mechanism of this effect remain largely unexplored. Here, the correlation between terminating strength and upstream mRNA stability was investigated by constructing a terminator mutation library through randomizing 5 nucleotides, assisted by FlowSeq technology, terminator variants were categorized based on the downstream fluorescence intensity, followed by high-throughput sequencing.

Impact of utilization of oxygen scavenger on aroma quality of Longjing tea during storage at elevated temperature.

The fresh aroma of Longjing tea is vulnerable to unfavorable storage conditions. However, limited research has addressed effective solutions apart from low-temperature storage. This study aimed to investigate the impact of oxygen scavenger on aroma quality of packaged Longjing tea samples at elevated storage temperatures.

Bacterial community improves the volatile components coupled with abiotic factors during the spontaneous fermentation of Chinese strong-aroma .

Flavor components largely depend on microbial activity and environmental conditions during traditional fermented food production. However, the microbial and abiotic contributions to the flavor of Chinese strong-aroma (SAB) remain poorly understood. In this study, the composition and functional profiles of the fungal and bacterial communities changed significantly after fourteen days of grain fermentation.

Assembly of oleosin during efficient extraction: Altering the sequence of defatting solvents.

During the extraction of membrane proteins from oil bodies (OBs), organic solvents dissolve the lipid core and precipitate proteins through solvent stress. Here the effects of solvent type and defatting sequence on the composition and structure of membrane proteins were investigated SDS-PAGE, FTIR, and SEM-EDS. High purity oleosin (86 %) was obtained by treatment first with a Floch solution and then with cold acetone and petroleum ether after twice washing OBs with urea.

Effects of exogenous selenium application on quality characteristics, selenium speciation, and in vitro bioaccessibility of rice pancakes.

Selenium is an essential trace element for human health. To date, a hotspot of functional foods is strengthening the content of organic Se in food using biological Se enrichment. Herein, Se-enriched rice pancakes were produced by directly adding different sodium selenite concentrations into the fermentation process.

Corrigendum to: Investigation of the Expression and Regulation of SCG5 in the Context of the Chromogranin-Secretogranin Family in Malignant Tumors.

An error was found in the affiliations of the author in the article titled 'Investigation of the Expression and Regulation of SCG5 in the Context of the Chromogranin-Secretogranin Family in Malignant Tumors'', published in Protein and Peptide Letters, 2024, 31(9), 657-666 [1]. Details of the error and a correction are provided here. Original: *Address correspondence to these authors at the Department of Thoracic Surgery, The Sixth Affiliated Hospital of Nantong University, Yancheng Third People's Hospital, Yancheng 224000, P.

Selective Adsorption of Chlorine Species on RuO Sites for Efficient Elimination of Vinyl Chloride on the Ru/SnO Catalyst.

The main bottleneck in the catalytic combustion of chlorinated volatile organic compounds (CVOCs) is deactivation and the production of chlorine-containing byproducts originating from the chlorine species deposited on the catalyst. Herein, Ru supported on SnO (Ru/SnO) was prepared with the lattice matching principle. As RuO and SnO are both rutile phases, Ru species were present as highly dispersed RuO particles on the Ru/SnO catalyst.

The highly pathogenic strain of porcine deltacoronavirus disrupts the intestinal barrier and causes diarrhea in newborn piglets.

Porcine deltacoronavirus (PDCoV) is increasingly prevalent in newborn piglets with diarrhea. With the development of research on the virus and the feasibility of PDCoV cross-species transmission, the biosafety and the development of pig industry have been greatly affected. In this study, a PDCoV strain CH/LNFX/2022 was isolated from diarrheal newborn piglets at a farm in China.

Constructing Three-Dimensional Porous SnS/RGO as Superior-Rate and Long-Life Anodes for Lithium-Ion Batteries.

Tin-based sulfides, possessing a unique layered structure and a high theoretical capacity, stand as highly prospective contenders for anode materials in lithium-ion batteries (LIBs). Nevertheless, the pronounced volume expansion that occurs during lithium storage and poor capacity retention have limited its progress toward commercialization. Herein, we designed and prepared a SnS/RGO composite with a three-dimensional porous structure by sulfurizing the SnO(OH)/GO precursor.

Encapsulation of biomimetic nanozymes in MOF matrices as peroxidase mimetics for sensitive detection of L-cysteine.

A metal-organic framework (MOF)-encapsulated nanozyme has been developed to detect L-cysteine (L-Cys) through a facile colorimetric sensing method in this study. This nanozyme was prepared by encapsulating Fmoc-histidine (FH) and hemin within ZIF-8 (FH/hemin@ZIF-8) and exhibited significantly enhanced catalytic activity and great stability because of its unique structure. FH/hemin@ZIF-8 oxidized colorless 3,3',5,5'-tetramethylbenzidine (TMB) to a distinct blue color with the assistance of HO.

sp. nov., a Al-tolerant bacterium with the ability to inhibit f. sp. isolated from rhizosphere soil of muskmelon.

A bacterial strain, designated as A6, was isolated from the rhizosphere soil of a healthy muskmelon in Wenchang, Hainan Province, China. The cells of strain A6 were Gram-negative, aerobic, short rod and motile with a single polar flagellum. Strain A6 could tolerate up to 55.

Global and Regional Burden of Type 2 Diabetes Mellitus Attributable to Low Physical Activity From 1990 to 2021.

Aim: Type 2 diabetes mellitus (T2DM) contributes to the heavy burden, but there lacks latest and comprehensive global research on the burden of T2DM attributable to low physical activity (LPA). This study aimed to quantify the global and regional burden of T2DM attributable to LPA from 1990 to 2021.

Methods: We utilized data including disability-adjusted life years (DALYs), mortality, age-standardized disability-adjusted life years (ASDR), and age-standardized mortality rates (ASMR) from the Global Burden of Disease (GBD) 2021.

A comparative study of gallic acid and its derivatives on the binding to Keap1 and their ability against 6-hydroxydopamine-induced cytotoxicity.

This study compared gallic acid (GLA) and its derivatives, i.e. ginnalin A (GA), 1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG), and (-)-epigallocatechin-3-gallate (EGCG) on their ability against 6-hydroxydopamine (6-OHDA)-induced cytotoxicity.

Physiological Insights Into the Role of Pericytes in Spinal Cord Injury.

Vascular regeneration plays a vital role in tissue repair yet is drastically impaired in those with a spinal cord injury (SCI). Pericytes are of great significance as they are entwined with vessel-specific endothelial cells and actively contribute to maintaining the spinal cord's vascular network. Within the neurovascular unit (NVU), subtypes of pericytes characterized by various markers such as PDGFR-β, Desmin, CD146, and NG-2 are involved in vascular regeneration in SCI repair.

From PD-1/PD-L1 to tertiary lymphoid structures: Paving the way for precision immunotherapy in cholangiocarcinoma treatment.

Cholangiocarcinoma (CCA) is a highly malignant hepatobiliary tumor characterized by limited treatment options and poor prognosis. The recent rise of immunotherapy has significantly influenced research in this field. This study presents a bibliometric analysis of 416 articles retrieved from the WOSCC, Wan fang Data, CNKI and VIP databases, spanning contributions from 32 countries, 589 institutions and 3,200 authors.

Microalgae-Derived Peptides: Exploring Bioactivities and Functional Food Innovations.

A variety of bioactive peptides with unique and diverse structures could be found in microalgae with various bioactivities including antioxidant, antihypertensive, and antibacterial bioactivities. Food products containing microalgae peptides hold significant health and nutrition potential. Peptide liberation through enzymatic and other processes enhanced protein extraction, and some animal studies were conducted to verify their health-promoting effects.