Stabilizing the Fe Species of Nickel-Iron Double Hydroxide via Chelating Asymmetric Aldehyde-Containing THB Ligand for Long-Lasting Water Oxidation.

Nickel-iron layered double hydroxides (NiFe LDHs) are considered as promising substitutes for precious metals in oxygen evolution reaction (OER). However, most of the reported NiFe LDHs suffer from poor long-term stability because of the Fe loss during OER resulting in severe inactivation. Herein, a dynamically stable chelating interface through in situ transformation of asymmetric aldehyde-ligand (THB, 1,3,5-Tris(3'-hydroxy-4'-formylphenyl)-benzene) modified NiFe LDHs to anchor Fe and significantly enhance the OER stability is reported.

Bioinspired Heterogeneous Surface for Radiative Cooling Enhanced Power-Free Moisture Harvesting in Unsaturated Atmosphere.

The development of zero-power moisture-harvesting technology in an unsaturated atmosphere is of great significance for coping with global freshwater scarcity. Here, inspired by Pachydactylus rangei's (Namib sand gecko) ability to evade thermal radiation and harvest moisture, a power-free cooling moisture harvester (PFCMH) is fabricated using the continuous, industrialized micro-extrusion compression molding. A Luneburg lens is introduced in the PFCMH for the first time, endowing it with a high reflectivity of ≈92.

Multi-Functional Semiconductor Polymer Doped Wide Bandgap Layer for All-Perovskite Solar Cells with High Efficiency and Long Durability.

The study presents a multi-functional and semiconductor polymer poly[bis(3-hexylthiophen-2-yl)thieno[3,4-c]pyrrole-4,6-dione] (PBDTTPD) doping strategy that significantly enhanced the performance of the two-terminal all-perovskite tandem perovskite solar cells (T-PSCs). An optimized power conversion efficiency (PCE) of 26.87% has been achieved.

Substrate-Mediated Growth of Au Nanowires Under Weak CTAB Control and Rapid Au Deposition.

The selective Au deposition at the Au-substrate interface is known to give ultrathin Au nanowires and the synthesis usually employs strong thiol-based ligands. It is shown that, by increasing the rate of Au deposition, weak cetyltrimethylammonium bromide (CTAB) can be made to behave like a strong ligand, so that it induces Active Surface Growth and gives Au nanowires. The ligand strength also depends on the packing interactions in the ligand layer, in the order of CTAB, CTAB, and CTAB.

Exposed weapons: A revised reconstruction of the facial anatomy and life appearance of the saber-toothed cat Megantereon (Felidae, Machairodontinae).

Megantereon was a widespread saber-toothed felid from the Pliocene and Pleistocene of the Old World and North America, but its rarity in the fossil record makes it complicated to restore its life appearance. Lack of complete specimens makes it necessary to combine information from fossils of different individuals to reconstruct their facial anatomy. In this work, we combine the analysis of skulls and mandibles of Megantereon from various fossil sites with the study of extant carnivorans through dissection, 3D scans, and the observation of live individuals.

Dynamic Lipidomics and Transcriptome Profiling Reveals the Transcriptional Regulatory Mechanism Governing TAGs Formation in Seeds of Safflower.

Safflower ( L.) is a valuable oil crop due to its bioactive ingredients and high linoleic acid content, which contribute to its antioxidant properties and potential for preventing atherosclerosis. Current research on safflower focuses on understanding the biosynthesis of seed oil through omics strategies, yet there is a lack of comprehensive knowledge of the dynamic changes in lipids and the regulatory mechanisms during seed development.

Robust Immobilization and Activity Preservation of Enzymes in Porous Frameworks by Silica-Based "Inorganic Glue".

The development of novel methods to enhance enzyme-carrier interactions in situ, at a feasible cost, and on a large scale is crucial for improving the stability and durability of current immobilized enzyme systems used in industrial settings. Here, a pioneering approach termed "silica-based inorganic glue" is proposed, which utilizes protein-catalyzed silicification to fix enzyme within porous matrix while preserving enzyme activity. This innovative strategy offers several key benefits, including conformational stabilization of enzymes, improved interactions between enzymes and the matrix, prevention of enzyme leakage, and mitigation of pore blocking.

Water-Enabled Electricity Generation by a Smooth Liquid-Like Semiconductor Coating Surface.

Water energy-converting techniques that focus on interfacial charge separation and transfer have aroused significant attention. However, the water-repelling nature leads to a less dense liquid layer and a sharp gradient of liquid velocity, which limits its output performance. Here, a water sliding generator (WSG) based on a smooth liquid-like/semiconductor surface (SLSS) is developed that harnesses the full advantage of liquid sliding friction.

Tailoring Acid-Salt Hybrid Electrolyte Structure for Stable Proton Storage at Ultralow Temperature.

The critical challenges in developing ultralow-temperature proton-based energy storage systems are enhancing the diffusion kinetics of charge carriers and inhibiting water-triggered interfacial side reactions between electrolytes and electrodes. Here an acid-salt hybrid electrolyte with a stable anion-cation-HO solvation structure that realizes unconventional proton transport at ultralow temperature is shown, which is crucial for electrodes and devices to achieve high rate-capacity and stable interface compatibility with electrodes. Through multiscale simulations and experimental investigations in the electrolyte employing ZnCl introduced into 0.

Temperature-Robust Broadband Metamaterial Absorber via Semiconductor MOFs/Paraffin Hybridization.

The demand for temperature-robust electromagnetic wave (EMW) absorption materials is escalating due to the varying operational temperatures of electronic devices, which can easily soar up to 100 °C, significantly affecting EMW interference management. Traditional absorbers face performance degradation across broad temperature ranges due to alterations in electronic mobility and material impedance. This study presented a novel approach by integrating semiconductor metal-organic frameworks (SC-MOFs) with paraffin wax (PW), leveraging the precise control of interlayer spacing in SC-MOFs for electron mobility regulation and the introduction of paraffin wax for temperature-inert electromagnetic properties.

Breaking the Ice: Hofmeister Effect-Inspired Hydrogen Bond Network Reconstruction in Hydrogel Electrolytes for High-Performance Zinc-Ion Batteries.

Gel electrolytes have emerged as a promising solution for enhancing the performance of zinc-ion batteries (ZIBs), particularly in flexible devices. However, they face challenges such as low-temperature inefficiency, constrained ionic conductivity, and poor mechanical strength. To address these issues, this study presents a novel PAMCD gel electrolyte with tunable freezing point and mechanical properties for ZIBs, blending the high ionic conductivity of polyacrylamide with the anion interaction capability of β-cyclodextrin.

Enhancing human ACE2 expression in mouse models to improve COVID-19 research.

Mice are one of the most common biological models for laboratory use. However, wild-type mice are not susceptible to COVID-19 infection due to the low affinity of mouse ACE2, the entry protein for SARS-CoV-2. Although mice with human ACE2 (hACE2) driven by Ace2 promoter reflect its tissue specificity, these animals exhibit low ACE2 expression, potentially limiting their fidelity in mimicking COVID-19 manifestations and their utility in viral studies.

Tea Polyphenol-Derived Carbon Dots Alleviate Abdominal Aortic Aneurysm Progression by Mitigating Oxidative Stress and Ferroptosis.

Abdominal aortic aneurysm (AAA) is a cardiovascular disease with potentially fatal consequences, yet effective therapies to prevent its progression remain unavailable. Oxidative stress is associated with AAA development. Carbon dots have reactive oxygen species-scavenging activity, while green tea extract exhibits robust antioxidant properties.

The effect and application of adiponectin in hepatic fibrosis.

Hepatic fibrosis, a degenerative liver lesion, significantly contributes to the deterioration and mortality among patients with chronic liver diseases. The condition arises from various factors including toxins, such as alcohol, infections like different types of viral hepatitis, and metabolic diseases. Currently, there are no effective treatments available for liver fibrosis.

LncRNA U731166 Increases the Accumulation of TGFBR1 by Sponging miR-3607-3p in Esophageal Squamous-Cell Carcinomas (ESCC) to Promote Tumor Metastasis.

Background: Long non-coding RNA (lncRNA) U731166 and microRNA (miR)-3607-3p are two ncRNAs with critical roles in cancer biology, while their involvement in esophageal squamous-cell carcinomas (ESCC) is unclear. We predicted that U731166 and miR-3607-3p might interact with each other. This study aimed to investigate their role and interaction in ESCC.

A Longitudinal Dynamic Change in LMR Can Be a Biomarker for Recurrence in Fusobacterium Nucleatum-Positive Colorectal Cancer Patients.

Purpose: This study assessed lymphocyte-to-monocyte ratio (LMR) changes to predict postoperative recurrence in Fusobacterium nucleatum-positive (Fn-positive) CRC patients.

Patients And Methods: Clinical information and paraffin tissue specimens were collected from a retrospective cohort of 332 patients. The abundance of Fn in tumor tissue was measured using a quantitative polymerase chain reaction.

Optomechanical energy enhanced BF-QEPAS for fast and sensitive gas sensing.

Traditional beat frequency quartz-enhanced photoacoustic spectroscopy (BF-QEPAS) are limited by short energy accumulation times and the necessity of a decay period, leading to weaker signals and longer measurement cycles. Herein, we present a novel optomechanical energy-enhanced (OEE-) BF-QEPAS technique for fast and sensitive gas sensing. Our approach employs periodic pulse-width modulation (PWM) of the laser signal with an optimized duty cycle, maintaining the quartz tuning fork's (QTF) output at a stable steady-state level by applying stimulus signals at each half-period and allowing free vibration in alternate half-periods to minimize energy dissipation.

Development of a predictive model for immune‑related adverse events in patients with cancer.

It is crucial to accurately identify patients with cancer at high risk for immune-related adverse events (irAEs) caused by immune checkpoint inhibitors (ICIs). The present retrospective study analyzed the risk factors for irAEs in 992 patients with cancer treated with ICIs at Xi'an International Medical Center Hospital from December 2021 to December 2023. The patients were categorized into one group that experienced irAEs (n=276) and a control group (n=716) based on the occurrence of irAEs.

Molecular mechanisms and therapeutic strategies of gut microbiota modulation in Sarcopenia (Review).

Sarcopenia is an age-related disease that is characterized by a decline in muscle mass and function with significant epidemiological and clinical implications. In recent years, gut microbiota has gained attention as an important regulatory factor in human health. To the best of our knowledge, this is the first study to introduce the definition and epidemiological background of sarcopenia and analyze the potential impact of the gut microbiota on muscle metabolism and growth, including aspects such as gut microbiota metabolites, muscle protein synthesis and energy metabolism.

Primary tracheal hyalinizing clear cell carcinoma with EWSR1 rearrangement: A case report.

Hyalinizing clear cell carcinoma (HCCC) is a rare, low-grade epithelial tumor predominantly found in the salivary glands, with tracheal involvement being particularly uncommon. The present study details a case of primary tracheal HCCC and its clinical presentation, diagnostic challenges and the therapeutic approach used. A 34-year-old female patient presented with a 1-month history of intermittent dyspnea.

Bronchial artery pseudoaneurysm presenting with hemoptysis and hemothorax after pulmonary lobectomy: a case report and literature review.

Background: Bronchial artery pseudoaneurysm is a rare vascular disorder, and cases of bronchial pseudoaneurysms reported after lung surgery are even rarer. The number of reported cases is very limited due to the unclear pathogenesis, lack of diagnostic criteria and treatment guidelines, and nonspecific clinical manifestations.

Case Presentation: The paper reports a case of a patient with primary lung adenocarcinoma who developed hemoptysis, chest and back pain, and right hemothorax after lobectomy.

Sex differences in the relationships between 24-h rest-activity patterns and plasma markers of Alzheimer's disease pathology.

Background: Although separate lines of research indicated a moderating role of sex in both sleep-wake disruption and in the interindividual vulnerability to Alzheimer's disease (AD)-related processes, the quantification of sex differences in the interplay between sleep-wake dysregulation and AD pathology remains critically overlooked. Here, we examined sex-specific associations between circadian rest-activity patterns and AD-related pathophysiological processes across the adult lifespan.

Methods: Ninety-two cognitively unimpaired adults (mean age = 59.

High prevalence of low bone mineral density in middle-aged adults in Shanghai: a cross-sectional study.

Purpose: To assess bone mineral density (BMD) in middle-aged individuals in Shanghai, in order to improve awareness of osteopenia and osteoporosis screening.

Methods: The clinical data of 1107 permanent residents of Shanghai aged 40-60 years were collected using a random cluster sampling method. Osteoporosis questionnaire survey and BMD test were conducted.