TiO/CoO heterostructure decorated MIL-100(Fe) by atomic layer deposition for enhanced photocatalytic oxygen production.

Efficient separation of photogenerated charge carriers is essential for maximizing the photocatalytic efficiency of semiconductor materials in oxygen evolution reactions (OER). This study presents a novel trimetallic photocatalyst, MIL-100(Fe)/TiO/CoO, synthesized through a facile microwave-assisted hydrothermal method followed by atomic layer deposition (ALD). The porous MIL-100(Fe) serves as a support for the sequential deposition of TiO and CoO layers ALD, which enhances electron-hole pair separation and minimizes their recombination.

Enhancing selectivity of β-O-4 bond cleavage for lignin depolymerization a sacrificial anode.

Herein, we report a novel electrochemical hydrogenolysis method for β-O-4 bond cleavage by using carbon foam as the cathode and waste aluminum as the anode. The reaction takes place at the cathode, producing ketones and phenolic compounds. Employing waste aluminum as the anode could avoid anodic excessive oxidation of phenols.

Base-Promoted [4 + 1 + 1] Multicomponent Tandem Cycloaddition of -Substituted Nitroarenes, Aldehydes, and Ammonium Salts To Access 2,4-Substituted Quinazoline Frameworks.

We report a base-promoted, metal-free multicomponent tandem reaction, involving a [4 + 1 + 1] cycloaddition process between -substituted nitroarenes, aldehydes, and ammonium salts. Modifying the substituents on the nitroaromatic compounds effectively provides structurally diverse 2-substituted and 4-alkenylquinazolines with good to excellent yields (77%-90% and quinazoline 51 examples) and high tolerance for various inorganic ammonium salts (13 examples, such as NH·HO, NHCl, and NHHF). A new method for constructing 2,4-substituted quinazoline compounds with high selectivity from simple nitrogen source compounds was developed, and the reaction can be scaled up to a gram scale.

Single and Synergistic Effects of Microplastics and Difenoconazole on Oxidative Stress, Transcriptome, and Microbiome Traits in Honey Bees.

Microplastics (MPs) and pesticides are identified as two environmental pollutants. In the present study, we showed evidence of toxic effects on honey bees from chronic oral exposure to food containing difenoconazole alone (Dif) and in a binary mixture with polystyrene (PS)-MPs (Dif + PS). We observed a disrupted gut microbial community structure in bees after difenoconazole exposure, and the gut microbiota structure richness increased at the phylum and genus levels in Dif + PS group.

Nanosecond Molecular Motion in pHP1α Liquid-Liquid Phase Separation Captured by Solid-State NMR.

The relationship among protein structure, function, and dynamics is fundamental to biological activity, particularly in more complex biomolecular systems. Solid-state and solution-state NMR techniques offer powerful means to probe these dynamics across various time scales. However, standard assumptions about molecular motion are often challenged in phase-separated systems like phosphorylated heterochromatin protein 1 alpha (pHP1α), which exhibit both solid- and solution-like characteristics.

Harnessing Hole Sites in 2D Monolayer C for Metal Cluster Anchoring.

Synthesis of 2D quasi-hexagonal phase C (qHP C) has opened avenues for its application as a novel catalytic support. This study investigates the structure, stability, and anisotropic properties of Cu clusters anchored on the qHP C surface through density functional theory calculations. Our findings reveal that the Cu cluster preferentially occupies the intrinsic holes of the qHP C via one of its tetrahedral faces, resulting in enhanced stability and conductivity, with a significantly reduced band gap of 0.

From Radical Coupling to Enantioselective Controlled Protonation: Advancing Precise Construction of Stereocenters.

Recent advancements in green and sustainable platforms, particularly visible light-driven photocatalysis, have spurred significant progress in radical chemistry, enabling the efficient synthesis of important molecules from simple and readily available feedstocks under mild conditions. However, the rapid orbital flipping and high reactivity of radicals pose substantial challenges for achieving precise enantiocontrol in stereocenter formation via radical coupling. In this study, we present a generic and efficient strategy that modulates this elusive approach, facilitating enantiocontrollable protonation through 1,3-boron migration.

m6A Demethylase -Mediated Upregulation of Induces Neuronal Ferroptosis via the Axis in the MPP/MPTP-Induced Parkinson's Disease Model.

: Parkinson's disease (PD) is a neurodegenerative disorder characterized by the involvement of ferroptosis in its pathological mechanism. In this study, the effects and mechanism of BRCA1-associated protein 1 (BAP1) on neuronal ferroptosis in PD were evaluated. : A PD mouse model was constructed by injecting mice with MPTP.

Nurses' Sleep Quality and Its Influencing Factors During the First Explosive COVID-19 Outbreak in Zhejiang, China, After the Relaxation of Epidemic Prevention and Control Measures: A Multicentre Cross-Sectional Study.

Aim: To investigate the sleep quality and its influencing factors among nurses in hospitals in Zhejiang, China, during the first explosive COVID-19 outbreak following the relaxation of prevention and control measures.

Design: A multicentre cross-sectional study.

Methods: Between 10 January and 20 January 2023-approximately 1 month after the policy was loosened-a total of 573 nurses from tertiary and community hospitals in Zhejiang participated in an online, self-administered survey.

Distinct Promotion of PEC Water Oxidation of TaO/α-FeO/Co-Ni PBA via Coupling Ni 3d with O 2p.

The development of robust and effective photoanodes is crucial for photoelectrochemical hydrogen production via total water splitting. Herein, the TaO/α-FeO/Co-Ni PBA (TFPB-1) photoanode was constructed by the compositing n-type TaO and n-type α-FeO followed by the deposition of p-type Co-Ni PBA. The IPCE of TFPB-1 was increased to 35.

Unveiling a Tunable Moiré Bandgap in Bilayer Graphene/hBN Device by Angle-Resolved Photoemission Spectroscopy.

Over the years, great efforts have been devoted in introducing a sizable and tunable band gap in graphene for its potential application in next-generation electronic devices. The primary challenge in modulating this gap has been the absence of a direct method for observing changes of the band gap in momentum space. In this study, advanced spatial- and angle-resolved photoemission spectroscopy technique is employed to directly visualize the gap formation in bilayer graphene, modulated by both displacement fields and moiré potentials.

NanoTrackThera Platform for Real-Time, In Situ Monitoring of Tumor Immunotherapy and Photothermal Synergistic Efficacy.

Cancer is one of the leading causes of death worldwide, posing a significant threat to human health. Although immunotherapy has shown promise in cancer treatment, its efficacy is often compromised by tumor immune evasion, which hinders treatment outcomes. Therefore, combining immunotherapy with other therapeutic approaches to enhance its effectiveness has become an increasingly accepted strategy in clinical practice.

High-Performance Proton Exchange Membrane with Vertically Aligned Montmorillonite Nanochannels.

The traditional perfluorosulfonic acid proton exchange membrane is crucial for proton exchange membrane fuel cells, but its high cost has impeded broader commercialization. In this study, a novel concept of a cost-effective and stable vertically aligned polydopamine-intercalated montmorillonite membrane (VAPMM) is introduced. 2D nanochannels formed within the lamellar structure of polydopamine-coated montmorillonite nanosheets provide a significant stable in-plane proton conductivity of 0.

Modulating Electronic Spin State of Perovskite Fluoride by Ni─F─Mn Bond Activating the Dynamic Site of Oxygen Reduction Reaction.

Establishing the relationship between catalytic performance and material structure is crucial for developing design principles for highly active catalysts. Herein, a type of perovskite fluoride, NHMnF, which owns strong-field coordination including fluorine and ammonia, is in situ grown on carbon nanotubes (CNTs) and used as a model structure to study and improve the intrinsic catalytic activity through heteroatom doping strategies. This approach optimizes spin-dependent orbital interactions to alter the charge transfer between the catalyst and reactants.

Nano-Metal-Organic Frameworks Isolated in Mesoporous Structures.

As an alternative to bulk counterparts, metal-organic framework (MOF) nanoparticles isolated within conductive mesoporous carbon matrices are of increasing interest for electrochemical applications. Although promising, a "clean" carbon surface is generally associated with poor compatibility and weak interactions with metal/ligand precursors, which leads to the growth of MOFs with inhomogeneous particle sizes on outer pore walls. Here, a general methodology for in situ synthesis of eight nanoMOF composites within mesochannels with high dispersity and stability are reported.

Maximizing Output Energy via Suppressing Charge Loss and Increasing Load Voltage in Charge Extraction Process.

The effective collection of interfacial tribo-charges and an increase in load voltage are two essential factors that improve the output energy of triboelectric nanogenerators. However, some tribo-charges are hardly collected through one or multiple integrated side electrodes based on corona discharge, and their load voltages are limited by air breakdown in adjacent electrodes. In this study, a dynamic quasi-dipole potential distribution model is proposed to systematically reveal the mechanisms of interfacial tribo-charge loss.

Stabilizing Layered Oxide Cathodes Based on Universal Surface Residual Alkali Conversion Chemistry for Rechargeable Secondary Batteries.

Layered transition metal oxides (LTMOs) are attractive cathode candidates for rechargeable secondary batteries because of their high theoretical capacity. Unfortunately, LTMOs suffer from severe capacity attenuation, voltage decay, and sluggish kinetics, resulting from irreversible lattice oxygen evolution and unstable cathode-electrolyte interface. Besides, LTMOs accumulate surface residual alkali species, like hydroxides and carbonates, during synthesis, limiting their practical application.

Directional Freeze-Casting Cryogel Loaded with Quaternized Chitosan Modified Gallium Metal-Organic Frameworks to Capture and Eradicate the Resistant Bacteria for Guided Regeneration in Infected Bone Defects.

Antimicrobial resistance and impaired bone regeneration are the great challenges in treating infected bone defects. Its recurrent and resistant nature, high incidence rate, long-term hospitalization, and high medical costs have driven the efforts of the scientific community to develop new therapies to improve the situation. Considering the complex microenvironment and persistent mechanisms mediated by resistant bacteria, it is crucial to develop an implant with enhanced osseointegration and sustained and effective infection clearance effects.

Bifunctional Group Modulation Strategy Enables MR-TADF Electroluminescence Toward BT.2020 Green Light Standard.

Herein, a parallel "bifunctional group" modulation method is proposed to achieve controlled modulation of the emission wavelength and full-width at half-maximum (FWHM) values. As a result, three proof-of-concept emitters, namely DBNDS-TPh, DBNDS-DFPh, and DBNDS-CNPh, are designed and synthesized, with the first functional dibenzo[b,d]thiophene unit concurrently reducing the bandgap and elevate their triplet state energy. A second functional group 1,1':3',1″-triphenyl, and electron acceptors 1,3-difluorobenzene and benzonitrile, respectively, to deepen the HOMO and LUMO levels.

Anti-Scattering Perovskite Scintillator Arrays for High-Resolution Computed Tomography Imaging.

Computed tomography (CT) imaging has emerge as an effective medical diagnostic technique due to its rapid and 3D imaging capabilities, often employing indirect imaging methods through scintillator materials. Arraying scintillators that can confine light scattering to enable high-resolution CT imaging remains an area of ongoing exploration for emerging perovskite scintillators. Here an anti-scattering cesium lead bromide (CsPbBr) scintillator array embedded within a polyurethane acrylate matrix for CT imaging using a cost-effective solution-processed method is reported.

Diatomite-Based Hybrid Electrolyte for Improving Reversibility of Cathode/Anode Interface Reaction in Zn-MnO Batteries.

The cyclic stability of aqueous zinc-manganese batteries (ZMBs) is greatly restricted by the side reaction of the anode and the irreversibility of the cathode. In this work, a solid-liquid hybrid electrolyte mixing by traditional ZnSO-based electrolyte and diatomite (denoted as Dtm) is proposed that exhibits good compatibility and reversibility in both the anode interface and the cathode interface. The abundant hydroxyl groups at the anode interface disturb the hydrogen bond network of water molecule, which weakens the corrosion of the active water to Zn anode.

Endogenous Protein-Modified Gold Nanorods as Immune-Inert Biomodulators for Tumor-Specific Imaging and Therapy.

Engineered modifications of nanomaterials inspired by nature hold great promise for disease-specific imaging and therapies. However, conventional polyethylene glycol modification is limited by immune system rejection. The manipulation of gold nanorods (Au NRs) modified by endogenous proteins (eP@Au) is reported as an engineered biomodulator for enhanced breast tumor therapy.

Synergistic Control of Ferroelectric and Optical Properties in Molecular Ferroelectric for Multiplexing Nonvolatile Memory.

Utilizing the correlation among diverse physical properties to facilitate multiplexing and multistate memory is anticipated to emerge as an efficient strategy to enhance memory capacity, achieve device miniaturization, and ensure information security. As an important functional material, ferroelectrics have long been considered as a potential candidate in multistate memory devices. Furthermore, the integration of optical response offers an alternative path to realizing multiplexing features, further enhancing the versatility and efficiency of these devices.

Extracellular matrix cancer-associated fibroblasts promote stromal fibrosis and immune exclusion in triple-negative breast cancer.

The impact of high heterogeneity of cancer-associated fibroblasts (CAFs) on triple-negative breast cancer (TNBC) immunotherapy response has not been fully elucidated, restricting progress in precision immuno-oncology. We integrated single-cell transcriptomic data from 18 TNBC patients and analyzed fibroblast subpopulations. Extracellular matrix CAFs (ecmCAFs) were identified as a fibroblast subpopulation with distinct ECM-associated characteristics.

Correction: Neuroprotective effects of fermented yak milk-derived peptide LYLKPR on HO-injured HT-22 cells.

Correction for 'Neuroprotective effects of fermented yak milk-derived peptide LYLKPR on HO-injured HT-22 cells' by Yunlong Jiang , , 2022, , 12021-12038, https://doi.org/10.1039/D2FO02131E.