Altered theta band and theta/beta ratio in mismatch negativity associate with treatment effect in schizophrenia with auditory hallucinations.

Evidence suggests that attenuated mismatch negative (MMN) waves have a close link to auditory verbal hallucinations (AVH) and their clinical outcomes, especially impaired neural oscillations such as θ, β representing attentional control. In current study, thirty patients with schizophrenia and AVH (SZ) and twenty-nine healthy controls (HC) underwent multi-feature MMN paradigm measurements including frequency and duration deviant stimuli (fMMN and dMMN). Clinical symptoms and MMN paradigm were followed up among SZ group after 8-week treatment.

Smaller sizes of polyethylene terephthalate microplastics mainly stimulate heterotrophic NO production in aerobic granular sludge systems.

Widespread polyethylene terephthalate microplastics (PET MPs) have played unintended role in nitrous oxide (NO) turnovers (i.e., production and consumption) at wastewater treatment plants (WWTPs).

An integrated strategy for sequential nitrite removal and methane recovery: Sludge fermentation driven by nitrite reduction.

Although the treatment of sludge with free nitrous acid can effectively recover short chain fatty acids, the feasibility of sequential nitrite reduction and methane recovery without acidic pH adjustment is still scarcely studied. Therefore, this study aimed to provide insights into the effect of nitrite at different levels on nitrite reduction and methane production. The results showed that the nitrite concentrations of 100, 200, 400 and 800 mg/L were completely reduced in 1, 2, 2 and 4 days, respectively.

Correction: Investigation of a flexible, room-temperature fiber-shaped NH sensor based on PANI-Au-SnO.

[This corrects the article DOI: 10.1039/D4RA06915C.].

Tetrazolium iridium complexes as potential antibacterial agents.

In this work, three iridium(iii) tetrazolato complexes have been used in antibacterial, biofilm removal and for other bioactivities for the first time. Notably, these iridium(iii) tetrazolato complexes with high antibacterial, especially, Ir-CFTAZ showed the best antimicrobial activity and the most effective hemolytic performance, which may pave the way to explore the value of the complexes for clinical applications in the future.

Correction: Three-dimensional TiNbO anchored on carbon nanofiber core-shell arrays as an anode for high-rate lithium ion storage.

[This corrects the article DOI: 10.1039/C9RA10485B.].

Cu/CuO/NH-MIL-88B (Fe) heterojunction as the photocatalyst to remove hexavalent chromium heavy metal ions in water.

This work aimed at addressing the problem of hexavalent chromium pollution in the water environment, designing and preparing the Cu/CuO/NH-MIL-88B (Fe) heterojunction material with NH-MIL-88B (Fe) as the carrier, Cu/CuO was loaded on NH-MIL-88B (Fe) by light-assisted reduction. The loading of CuO effectively improves the visible light absorption capacity of the composite material. The SPR effect of Cu improves the separation and transfer of photogenerated carriers in the composite material.

Changes in flavor profile of sauce-flavor baijiu: Perceptual interactions between 1-propanol and aroma compounds.

1-Propanol is an important aroma compound in sauce-flavor Baijiu. However, the mechanism by which it affects the aroma of sauce-flavor Baijiu has not been fully investigated. In this study, an instrumental and perceptual analysis was employed to assess the impact of 1-propanol on the flavor and volatile compounds in sauce-flavor Baijiu.

Vertical flow immunoassay for multiplex mycotoxins based on photonic nitrocellulose and SERS nanotags.

Here, we report a SERS based VFA using PNC as a sensing substrate for highly sensitive multiplex mycotoxins detection. The PNC was fabricated by filtration-based self-assembled monodisperse SiO NPs on a filter membrane as a template, and the obtained PNC had an ordered complementary inverse opal structure. In parallel, three kinds of Raman dyes encoding Au@Ag, Au@Ag and Au@Ag SERS nanotags were synthesized for the detection of OTA, AFB1 and ZON.

Rapid introgression of the clubroot resistance gene into cabbage skeleton inbred lines through marker assisted selection.

Unlabelled: Clubroot, caused by , is a globally pervasive soil-borne disease that poses a significant challenge primarily in cruciferous crops. However, the scarcity of resistant materials and the intricate genetic mechanisms within cabbage present major obstacles to clubroot resistance (CR) breeding. In our previous research, we developed an Ogura CMS cabbage variety, "17CR3", which harbors the gene, crucial for CR.

3D printing of biological tooth with multiple ordered hierarchical structures.

Natural teeth fulfill functional demands by their heterogeneity. The composition and hydroxyapatite (HAp) nanostructured orientation of enamel differ from those of dentin. However, mimicking analogous materials still exhibit a significant challenge.

Click chemistry-enabled gold nanorods for sensitive detection and viability evaluation of copper(II)-reducing bacteria.

The rise of antibiotic resistance poses a significant and ongoing challenge to public health, with pathogenic bacteria remaining a persistent threat. Traditional culture methods, while considered the gold standard for bacterial detection and viability assessment, are time-consuming and labor-intensive. To address this limitation, we developed a novel point-of-care (POC) detection method leveraging citrate- and alkyne-modified gold nanorods (AuNRs) synthesized with click chemistry properties.

Stem cell-derived exosome delivery systems for treating atherosclerosis: The new frontier of stem cell therapy.

Cardiovascular diseases (CVDs) are a leading cause of mortality worldwide. As a chronic inflammatory disease with a complicated pathophysiology marked by abnormal lipid metabolism and arterial plaque formation, atherosclerosis is a major contributor to CVDs and can induce abrupt cardiac events. The discovery of exosomes' role in intercellular communication has sparked a great deal of interest in them recently.

A Pair of Fluorescent Probes Enabling Precise Diagnosis of Liver Cancer by Complementary Imaging.

Hepatocellular carcinoma (HCC) is by far the predominant malignant liver cancer, with both high morbidity and mortality. Early diagnosis and surgical resections are imperative for improving the survival of HCC patients. However, limited by clinical diagnosis methods, it is difficult to accurately distinguish tumor tissue and its boundaries in the early stages of cancer.

Facile Labeling of Gram-Negative Bacteria with NIR-II Fluorescent Nanoprobes for Intestinal Bacteria Imaging.

The gut bacteria not only play a crucial role in maintaining human health but also exhibit close associations with the occurrence of numerous diseases. Understanding the physiological and pathological functions of gut bacteria and enabling early diagnosis of gut diseases heavily relies on accurate knowledge about their in vivo distribution. Consequently, there is a significant demand for noninvasive imaging techniques capable of providing real-time localization information regarding gut bacteria.

Identifying Natural Products as Feline Coronavirus M Inhibitors by Structural-Based Virtual Screening and Enzyme-Based Assays.

The main protease (M) is a pivotal target in the life cycle of feline coronavirus (FCoV), which causes a high mortality feline disease, feline infectious peritonitis (FIP). Virtual screening was performed against the feline coronavirus M to find active compounds with low toxicity from a library of natural products. Eighty-six compounds were selected by using the rank of docking score and binding pose analysis.

Neutrophil-derived apoptotic body membranes-fused exosomes targeting treatment for myocardial infarction.

Myocardial infarction (MI) poses a substantial threat to human health, prompting extensive research into effective treatment modalities. Preclinical studies have demonstrated the therapeutic potential of mesenchymal stem cell-derived exosomes for cardiac repair. Despite their promise, the inherent limitations of natural exosomes, mainly their restricted targeting capabilities, present formidable barriers to clinical transformation.

Deep Learning and Radiomics in Triple-Negative Breast Cancer: Predicting Long-Term Prognosis and Clinical Outcomes.

Triple-negative breast cancer (TNBC) is a unique breast cancer subtype characterized by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression in tumor cells. TNBC represents about 15% to 20% of all breast cancers and is aggressive and highly malignant. Currently, TNBC diagnosis primarily depends on pathological examination, while treatment efficacy is assessed through imaging, biomarker detection, pathological evaluation, and clinical symptom improvement.

Methodological study on coal-based microbial modification of mineral black clay to overcome plant growth challenges on open-pit mine dumps in cold regions.

A critical challenge in ecological restoration of open-pit mine dumps in cold regions with limited topsoil resources is how to rapidly mitigate the plant growth-inhibitory effects of mineral black clay, thereby converting it into arable soil. Leveraging the high degradation capacity of coal seam-associated microorganisms on fossil carbon materials, combined with soil conditioning techniques, this study developed a microbial-based approach for modifying black clay. Seed germination experiments informed both laboratory and field trial designs.

Clinical Significance of the Peripheral Blood Neutrophil-to-Lymphocyte Ratio in Predicting Chemotherapy Outcomes for Small Cell Lung Cancer.

Objective: This study aims to assess the clinical significance of the peripheral blood neutrophil-to-lymphocyte ratio (NLR) in predicting chemotherapy outcomes for patients with small cell lung cancer (SCLC).

Methods: A cohort of 44 patients diagnosed with SCLC between January 2021 to June 2022 at Fuyang People's Hospital was selected for analysis. All patients in this group received a first-line platinum-based doublet chemotherapy regimen.

Recent developments and challenges of molecular design in linear cyanido-bridged multimetallic complexes.

Cyanido-bridged multimetallic complexes have been extensively studied for their potential applications in molecular electronics and spintronics. The design of these complexes involves the strategic placement of metal centers and the use of cyanide bridges to facilitate electron transfer between metal ions. The challenges in this field include the precise control of the electronic states and the stability of the complexes under various conditions.

Effects of porous hedgehog-like morphology and graphene oxide on the cycling stability and rate performance of CoO/NiO microspheres.

A porous hedgehog-like CoO/NiO/graphene oxide (denoted as PHCNO/GO) microsphere was prepared by a facile solvothermal method, followed by an annealing treatment under argon atmosphere. Benefiting from the thin CoO/NiO nanosheets with a large specific surface area, abundant pores distributed between the CoO/NiO nanosheets, and GO firmly wrapped around the surface of PHCNO microspheres, the PHCNO/GO microspheres showed excellent lithium storage performance. The CoO/NiO nanosheets provided numerous active sites, achieving a high reversible specific capacity.

Developing tough, fatigue-resistant and conductive hydrogels growth of metal dendrites.

Developing hydrogels with high conductivity and toughness a facile strategy is important yet challenging. Herein, we proposed a new strategy to develop conductive hydrogels by growing metal dendrites. Water-soluble Sn ions were soaked into the gel and then converted to Sn dendrites an electrochemical reaction; the excessive Sn ions were finally removed by water dialysis, accompanied by dramatic shrinkage of the gel.

An isolable boron-centered radical anion stabilized by a carbazole moiety.

The isolation of a stable persistent carbazole-stabilized boron-centered monoradical anion 1˙, which has a high spin density at the B atom, has been reported. It is characterized using the crystal structure and UV-vis absorption spectrum, as well as electron paramagnetic resonance spectroscopy. Interestingly, the B-N bond was activated by the boron-centered radical anion 1˙, which had not been reported before.