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A Systematic Review of Tumor Necrosis Factor-α in Post-Traumatic Stress Disorder: Evidence from Human and Animal Studies.

Psychiatr Danub

December 2017

Department of Psychological Medicine, King's College London, PO59 Institute of Psychiatry, Psychology & Neuroscience, De Crespigny Park, London SE5 8AF, UK.

Background: Growing evidence suggests a pathophysiological role of cytokines in post-traumatic stress disorder (PTSD). Tumor necrosis factor (TNF)-α is a key cytokine. Therefore, we performed a systematic review to examine the findings regarding TNF-α derived from both animal and human studies of PTSD.

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