Molecular Phosphide Complexes of Zirconium.

Molecular Zr phosphides are extremely rare, with no examples containing a one-coordinated and terminal triple-bonded phosphorus atom. We report here an isolable and relatively stable Zr phosphide complex, [(PN)Zr≡P{μ-Na(OEt)}] (), stemming from a cyclometalated Zr-hydride, [(PN)(PN')Zr(H)] (), and NaPH. Complex is prepared from two- or one-electron reductions of precursors [(PN)ZrCl] () or metastable Zr[(PN)ZrCl], respectively.

and are robust biomarkers for gingivitis and periodontitis in small dogs.

Introduction: Periodontal disease is one of the most common oral diseases in dogs and humans. It starts with gingivitis, a reversible condition, and progresses to an irreversible condition, periodontitis. Unlike humans, the etiology of periodontal disease in dogs has not been widely studied.

Positive selection on mammalian immune genes-effects of gene function and selective constraint.

Genome-wide analyses of various taxa have repeatedly shown that immune genes are important targets of positive selection. However, little is known about what factors determine which immune genes are under positive selection. To address this question, we here focus on the mammalian immune system and investigate the importance of gene function and other factors like gene expression, protein-protein interactions, and overall selective constraint as determinants of positive selection.

Gut bacterium Intestinimonas butyriciproducens improves host metabolic health: evidence from cohort and animal intervention studies.

Background: The human gut microbiome strongly influences host metabolism by fermenting dietary components into metabolites that signal to the host. Our previous work has shown that Intestinimonas butyriciproducens is a prevalent commensal bacterium with the unique ability to convert dietary fructoselysine to butyrate, a well-known signaling molecule with proven health benefits. Dietary fructoselysine is an abundant Amadori product formed in foods during thermal treatment and is part of foods rich in dietary advanced glycation end products which have been associated with cardiometabolic disease.

Effects of improved partner notification on the transmission of HIV and among men who have sex with men: a modelling study.

Men who have sex with men (MSM) are disproportionally affected by HIV in the Netherlands. Partner notification (PN) is an important element in controlling the transmission of sexually transmitted infections (STIs) and HIV. We investigated the effects of improving PN on the transmission of HIV and (NG) among MSM in the Netherlands.

The clinical significance of mirror patterns of cerebrospinal fluid oligoclonal immunoglobulin G bands (IgG-OCBs) in peripheral neuropathy disorders.

Background: CSF (cerebrospinal fluid) oligoclonal immunoglobulin G bands (IgG-OCBs) analysis plays a crucial role in diagnosis of various neurological disorders. However, the clinical significance of mirror pattern bands remains unclear, and their precise application is not well understood.

Methods: We retrospectively reviewed a total of 7597 IgG-OCB records detected using isoelectric focusing from May 2020 and August 2023 at Huashan Hospital.

Histopathologic Progression and Metastatic Relapse Outcomes in Small Cell Neuroendocrine Carcinomas of the Urinary Tract.

Introduction: Small cell neuroendocrine carcinoma of the urinary tract (SCNEC-URO) has an inferior prognosis compared to conventional urothelial carcinoma (UC). Here, we evaluate the predictors and patterns of relapse after surgery.

Materials And Methods: We identified a definitive-surgery cohort (n = 224) from an institutional database of patients with cT1-T4NxM0 SCNEC-URO treated in 1985-2021.

Root functional traits are important predictors for plant resource acquisition strategies in subtropical forests.

Intercorrelated aboveground traits associated with costs and plant growth have been widely used to predict vegetation in response to environmental changes. However, whether underground traits exhibit consistent responses remains unclear, particularly in N-rich subtropical forests. Responses of foliar and root morphological and physiological traits of tree and herb species after 8-year N, P, and combined N and P treatments (50 kg N, P, N and P ha year) were examined in leguminous Acacia auriculiformis (AA) and nonleguminous Eucalyptus urophylla (EU) forests in southern China.

A Retrospective Analysis of Morbidity and Risk Factors of Multiple Myeloma with Peripheral Neuropathy.

Peripheral nerve injury affects some people with multiple myeloma; this condition can be brought on by the disease itself or by the treatments they receive. Such a complication increases patients' financial burden, causes treatment to be interrupted or delayed, and reduces treatment efficacy. However, opinions regarding the risk factors for peripheral neuropathy are currently divided.

PbS@NiFe-LDH heterojunction: an efficient photo-assisted electrocatalyst for the OER.

Recently, photo-assisted electrocatalysis as an emerging catalytic approach that combines the technologies of photocatalysis and electrocatalysis has attracted great interest among researchers. Under this circumstance, the NiFe-LDH compounded with PbS based (PbS@NFHS) heterojunction with both photoactive and electrocatalytic properties was constructed for the first time through an ambient etching route and a subsequent low-temperature hydrothermal method. The as-prepared catalyst displayed a novel hierarchical 3D open structure based on nanosheets, which offered numerous electrochemically active sites, facilitated the swift diffusion of ions and enhanced both electrical conductivity and catalytic stability, thus significantly improving the catalytic performance.

Role of Adenosine A1 Receptor in Sleep Deprivation-Induced Neuroinflammation: Insights on Rapid Eye Movement Sleep and Fear Extinction Memory Recall in Rats.

Introduction: Sleep deprivation (SD), stemming from a myriad of aetiologies, is a prevalent health condition frequently overlooked. It typically impairs memory consolidation and synaptic plasticity, potentially through neuroinflammatory mechanisms and adenosinergic signalling. It is still unclear whether the adenosine A1 receptor (A1R) modulates SD-induced neurological deficits in the hippocampus.

Integrated serum pharmacochemistry, pharmacokinetics, and network analysis to explore active components of BuShao Tiaozhi Capsule on hyperlipidemia.

BuShao Tiaozhi Capsule (BSTZC), a novel drug in China, has been used to treat hyperlipidemia (HLP) in clinical practice for many years. Despite our previous studies suggesting that BSTZC can treat HLP, there is a lack of a rapid and systematic method to explore its active components. Therefore, in this study, we aimed to investigate the active components and mechanisms of BSTZC in treating HLP by integrating serum pharmacology, pharmacokinetics, network analysis, and experimental validation.

Engineering of Cd Zn S Nanomaterials for Fabrication of Hybrid Cd Zn S/Si Heterojunction Broadband Photo Detectors.

Effective engineering of nanostructured materials provides a scope to explore the underlying photoelectric phenomenon completely. A simple cost-effective chemical reduction route is taken to grow nanoparticles of Cd Zn S with varying = 1, 0.7, 0.

Genomic scans for selection and runs of homozygosity in southern Italian turkey populations.

Basilicata and Apulian (BAS-APU) turkeys, a native population in the Basilicata and Puglia regions of southern Italy, are known for their high meat quality and tolerance to local conditions. Understanding the genomic patterns of BAS-APU turkeys is critical for effective breeding and preservation strategies. In this study, we characterized runs of homozygosity (ROH), and selection signatures using the integrated haplotype score (iHS) and ROH approaches.

A meta-analysis of the utility of cryotherapy for preventing peripheral neuropathy among breast cancer patients receiving paclitaxel and nab-paclitaxel.

Background: Cryotherapy with taxane infusion is a noninvasive strategy for preventing peripheral neuropathy (PN), but the efficacy of this approach has not been proven.

Methods: A systematic search was conducted, and 477 records were initially identified. The titles were screened independently by 2 reviewers.

Apigenin enhancing oxidative resistance and proteostasis to extend lifespan via PTEN-mediated AKT signalling pathway.

Aging is a complicated process, featuring the progressive deterioration of physiological functions and a heightened susceptibility to diseases including neurodegenerative disorders, cardiovascular diseases, and cancer. Apigenin, a flavonoid existing in various plants, has attracted attention due to its potential role in anti-aging. In this investigation, the potential effect of apigenin on extending lifespan in Saccharomyces cerevisiae (yeast) and Drosophila melanogaster (flies) was explored.

Comparison of Piperacillin-tazobactam and Vancomycin (TZP-VAN) with Piperacillin-tazobactam and Teicoplanin (TZP-TEI) for the risk of Acute Kidney Injury (CONCOMITANT): A prospective observational, multinational, multi-centre cohort study.

Objectives: Both vancomycin (VAN) and teicoplanin (TEI) augment the risk of acute kidney injury (AKI) when combined with piperacillin-tazobactam (TZP). We aimed to compare the risk of AKI among patients receiving TZP-VAN versus TZP-TEI.

Methods: This was a prospective, multinational, multicentre cohort study conducted in 12 centres from Turkiye, Italy and Spain between June 1, 2022, and December 31, 2023.

Molecular clustering on ctDNA improves the prognostic stratification of DLBCL patients compared to ctDNA levels.

Circulating tumor DNA (ctDNA) levels can help predict outcomes in diffuse large B-cell lymphoma (DLBCL), but its integration with DLBCL molecular clusters remains unexplored. Using the LymphGen tool in 77 DLBCL with both ctDNA and tissue biopsy, a 95.8% concordance rate in molecular cluster assignment was observed, showing the reproducibility of molecular clustering on ctDNA.

Prognostic relevance of lymph node metastasis in pancreaticoduodenectomy for distal cholangiocarcinoma: Rational extent and number-based nodal classification for regional lymphadenectomy.

Background: We investigated the rational extent of regional lymphadenectomy and evaluated the prognostic impact of number-based regional nodal classification in patients with distal cholangiocarcinoma.

Methods: This study included 191 patients with distal cholangiocarcinoma who underwent pancreaticoduodenectomy. The nos.

-Loaded Easily Injectable Hydrogel Promotes Endometrial Repair via Long-Term Retention and Microenvironment Modulation.

Regeneration of the injured endometrium, particularly the functional layer, is crucial for the prevention of uterine infertility. At present, clinical treatment using sodium hyaluronate hydrogel injection is limited by its relatively low fluidity, short-term retention, and insufficient bioactive ingredients, so it is necessary to develop an advanced healing-promoting hydrogel. The modulation of the microenvironment by presents a bioactive component that can facilitate the regeneration of the functional layer.

A Rare Case of Perineurioma of the Posterior Interosseous Nerve: A Case Report.

The perineurioma (PN) is a benign neoplasm with perineural origin. It can be of two types, i.e.

Characterizing Household Perceived Evacuation Behaviors in the United States During the COVID-19 Pandemic: 2020-2021.

Objective: Evacuation can reduce morbidity and mortality by ensuring households are safely out of the path of, and ensuing impacts from, a disaster. Our goal was to characterize potential evacuation behaviors among a nationally representative sample.

Methods: We added 10 questions to the existing Porter Novelli's (PN) ConsumerStyles surveys in Fall 2020, Spring 2021, and Fall 2021.