6 results match your criteria: "PLdlJ); and Vision Cooperative Research Centre[Affiliation]"
Comparative Analysis of Adverse Events From a Series of Proof-of-Principle Extended Wear Studies.
Eye Contact Lens
March 2019
School of Optometry and Vision Science (J.O., P.L.d.l.J., M.W.), University of New South Wales, Sydney, New South Wales, Australia; Currently Director of Research Programs (P.L.d.l.J.), CooperVision, Pleasanton, CA.
Aim: A series of proof-of-principle extended wear (EW) contact lens studies were conducted to assess what effect different interventions had on adverse events (AEs). Comparative analysis of AEs across studies was conducted to determine whether some interventions were more effective at reducing inflammatory AEs.
Method: Multiple logistic regression analysis of AEs from 30-day EW studies each with a different intervention including (1) nightly replacement (NR) of lenses, (2) morning replacement (MR) of lenses, (3) instillation of prophylactic antibiotic drops (AB) each morning/evening, (4) daily lens cleaning (LC) each morning.
Demographic Factors Affect Ocular Comfort Ratings During Contact Lens Wear.
Optom Vis Sci
August 2016
*PhD †PhD, FAAO Brien Holden Vision Institute, Sydney, New South Wales, Australia (TN, EBP, PLdlJ); School of Optometry and Vision Science, University of New South Wales, Sydney, New South Wales, Australia (EBP, PLdlJ); and Vision Cooperative Research Centre, Sydney, New South Wales, Australia (EBP, PLdlJ).
Purpose: To determine if rating of ocular comfort during soft contact lens wear is affected by demographic factors.
Methods: Retrospective analysis of ocular comfort ratings during soft contact lens wear extracted from 44 nonrandomized similar clinical trials (n = 986). Subjects wore one of seven daily wear silicone hydrogels (SiHy) in combination with one of nine lens care products (LCP), and two daily disposables lenses.
Ocular discomfort responses after short periods of contact lens wear.
Optom Vis Sci
June 2015
*PhD, FAAO †MOptom, FAAO ‡OD, FAAO §PhD Brien Holden Vision Institute, Sydney, New South Wales, Australia (EP, DT, PLdlJ); Vision Cooperative Research Centre, Sydney, Australia (EP, PLdlJ); School of Optometry and Vision Science, University of New South Wales, Sydney, New South Wales, Australia (EP, PLdlJ); and CIBA Vision, Duluth, Georgia (JMc).
Purpose: To investigate if contact lens-related discomfort is a function of the time of day at which lenses are worn.
Methods: This was a randomized, crossover, open-label clinical trial where subjective responses, with and without contact lenses, were assessed every 2 hours during five stages (A to E). Each stage began at the time when subjects would normally have inserted their contact lenses (T0).
The effect of compliance on contact lens case contamination.
Optom Vis Sci
March 2014
*BOptom(Hons), MOptom †PhD, FAAO ‡PhD Brien Holden Vision Institute (DT, PLdlJ, HZ, TJN, BAH), Sydney, New South Wales, Australia; School of Optometry and Vision Science (PLdlJ, BAH), University of New South Wales, Sydney, New South Wales, Australia; and Vision Cooperative Research Centre (BAH), Sydney, New South Wales, Australia.
Purpose: To determine the efficacy of written instructions on contact lens case hygiene and to quantify the effect of noncompliance on contact lens case contamination.
Methods: Data were retrospectively analyzed from 16 prospective, 3-month daily-wear studies during which six commercially available silicone hydrogel contact lenses and seven lens care solutions (LCS) were tested following a similar protocol. Verbal instructions regarding case hygiene (rinse case with LCS, not tap water) were given in nine studies, while the same instructions were given verbally and in written format in seven studies.
Short-term clinical comparison of two dual-disinfection multipurpose disinfecting solutions.
Eye Contact Lens
January 2014
Brien Holden Vision Institute (D.T., P.L.d.l.J., R.W., T.N.), Sydney, New South Wales, Australia; and School of Optometry and Vision Science (P.L.d.l.J., M.D.P.W.), University of New South Wales, Sydney, New South Wales, Australia.
Objective: To compare the short-term clinical performance of two dual-disinfectant multipurpose disinfecting solutions (MPDS) when used in conjunction with two silicone hydrogel contact lenses.
Methods: Participants wore galyfilcon A and balafilcon A lenses, randomly allocated one type to each eye. Multipurpose disinfecting solutions were double-masked and allocated using a randomized crossover design.
Effect of antibiotic drops on adverse events during extended lens wear.
Optom Vis Sci
January 2014
*BOptom †PhD, FBCLA, FAAO, MASM ‡MBBS, DO §BSc(Optom) ∥PhD **PhD, DSc, FAAO Brien Holden Vision Institute (JO, HZ, PLdlJ, TN, BAH); and School of Optometry and Vision Science, University of New South Wales (JO, MDPW, HZ, PLdlJ, BAH), Sydney, New South Wales, Australia; and LV Prasad Eye Institute (VR, DS), Hyderabad, India.
Purpose: Overnight lens wear is associated with increased lens contamination and risk of developing a corneal infiltrate or infectious event. Antibacterial lenses have been proposed as a potential strategy for reducing lens contamination. A proof-of-principle study was conducted to investigate what effect control of potential pathogens, through the use of antibiotic eye drops, would have on the incidence of corneal infiltrative events (CIEs) and on the ocular microbiota and lens contamination.
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