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[The characterization of regulatory T cells in peripheral blood of HBV-infected patients].

Zhonghua Yi Xue Za Zhi

June 2006

Research Center of Biological Therapy and the Sixth Department of Infectious Diseases, 302 Hospital, PLA Postgrduate Medical School, Beijing 100039, China.

Objective: CD4(+)CD25(high) regulatory T cells (Treg) have been shown to play an important role in maintaining peripheral tolerance against self and foreign antigens, and in suppressing T cell immune response. Our aim was to characterize circulating Treg in HBV-infected patients.

Methods: Treg in peripheral blood from 72 chronic hepatitis B (CHB) patients, 16 acute hepatitis B (AHB) patients and 32 healthy subjects were quantitatively analyzed using flow cytometry.

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