[Growth factors may enhance c-fos and c-jun gene expressions of hepatic stellate cells].

Objective: To investigate the effects of growth factors on c-fos and c-jun gene expressions in hepatic stellate cells.

Methods: Hepatic stellate cell (HSC) T6 was cultured in media containing different concentrations of platelet derived growth factor (PDGF) (8 ng/ml, 40 ng/ml or 200 ng/ml) and transforming growth factor (TGF) beta (0.2 ng/ml, 1 ng/ml or 5 ng/ml) and the cells were collected at different incubation periods (8, 24, 48 or 72 h).