1 results match your criteria: "PJ Safarik University in Kosice and Children's University Hospital[Affiliation]"
Polymorphisms at 1q32, 8q24, and 17q22 loci are associated with nonsyndromic cleft lip with or without cleft palate risk in the Slovak population.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
June 2017
Department of Paediatrics, Faculty of Medicine, PJ Safarik University in Kosice and Children's University Hospital, Kosice, Slovak Republic.
Article Synopsis
- Nonsyndromic cleft lip with or without cleft palate (nsCL/P) is a common birth defect influenced by genetic and environmental factors, with several genetic variants linked to its risk.
- The study focused on four specific single nucleotide polymorphisms (SNPs) identified in previous research and analyzed their association with nsCL/P in a Slovak population.
- Significant differences were found in allele and genotype frequencies for three SNPs, suggesting they may increase the risk of nsCL/P, while one SNP displayed a trend toward association.