1 results match your criteria: "P.J. Šafárik University and L. Pasteur University Hospital[Affiliation]"
Association of JAG1 gene polymorphism with systemic blood pressure in patients with obstructive sleep apnea: a prospective cohort study.
Croat Med J
October 2019
Pavol Joppa, Department of Pneumology and Phtiseology, Medical Faculty of P. J. Šafárik University and L. Pasteur University Hospital in Košice, Rastislavova 43, Košice SK-04190, Slovakia,
Aim: To assess the effects of single nucleotide polymorphisms (SNPs) on blood pressure control in patients with obstructive sleep apnea (OSA).
Methods: This prospective observational cohort study, conducted between 2004 and 2014, examined the associations of SNPs of JAG1, GUCY1A3-GUCY1B3, SH2B3, and NPR3-C5orf23 genes with systolic and diastolic blood pressure (SBP, DBP) in 1179 adults evaluated for OSA with overnight polysomnography. Genotyping was performed by unlabeled probe melting analysis.