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Objective: To determine the effects of premolar and additional first molar extractions (AFMEs) on soft tissue changes after four premolar extractions in high Angle Class II division 1 patients.

Materials And Methods: Thirty-three AFME patients, 24 of who had maxillary-only AFME and 9 of who had all-four AFME, were studied by cephalometric analysis and compared with 43 patients treated with four premolar-only extractions (PRMEs) as a control group. Lateral cephalograms taken at four time points-pretreatment, before AFME, posttreatment, and retention-were utilized for statistical analysis by Student's t-test.

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