1,194 results match your criteria: "Ovarian Vein Thrombosis"

Acute Epiploic Appendagitis Mimicking Ovarian Torsion: A Case Report Highlighting Diagnostic Challenges.

Am J Case Rep

December 2024

Department of Obstetrics and Gynaecology, Raigmore Hospital, NHS Highland, Inverness, United Kingdom.

BACKGROUND Acute epiploic appendagitis is an uncommon cause of acute abdominal pain characterized by pain in the left or right lower quadrants of the abdomen. It is caused by torsion or spontaneous venous thrombosis of one of the epiploic appendages, which are found along the colon, most commonly in the sigmoid colon. The literature consistently compares the presenting symptoms and clinical picture of acute epiploic appendagitis to acute diverticulitis and acute appendicitis.

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Phlegmasia cerulea dolens is a rare manifestation of massive deep vein thrombosis with threat to limb and life. A patient with a background of ovarian malignancy in remission and pelvic radiotherapy presented with left lower limb phlegmasia cerulea dolens as a result of extensive acute left lower limb deep vein thrombosis, extending from the popliteal vein to the inferior vena cava. While initial rapid thrombolysis and left iliac vein stenting were successful, she developed significant hemorrhagic complications from her right radial intra-arterial line with compartment syndrome requiring fasciotomy.

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Ischemic events are infrequent in patients with ovarian hyperstimulation syndrome.

J Stroke Cerebrovasc Dis

September 2024

Clinical and Translational Neuroscience Unit, Department of Neurology, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, 520 East 70th Street, Starr Pavilion, 607, New York, NY, 10021, USA. Electronic address:

Background: Case reports describe arterial thrombosis including ischemic stroke associated with severe ovarian hyperstimulation syndrome (OHSS), but the prevalence of major ischemic events during or shortly after OHSS is unknown.

Methods: Using publicly available administrative datasets in the United States between 2015 and 2020, we conducted two separate cross-sectional studies of patients with OHSS. We included all patients with OHSS.

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Circulating exosomal protein EFEMP1 and SERPINC1 as diagnostic biomarkers for epithelial ovarian cancer.

Transl Oncol

December 2024

Department of Clinical Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, PR China. Electronic address:

Objectives: Caner-derived exosomes, containing diverse nucleic acids and proteins, are being exploited in diagnostic biomarker development. This study aims to screen and identify the altered exosomal proteins between epithelial ovarian cancer (EOC) patient and healthy volunteers, and to evaluate their diagnostic accuracy for EOC.

Methods: Exosomes were separate by ultracentrifugation, and then subjected to TEM, qNano, and western blot for identification.

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Hepatic mobilization is essential in debulking surgery for resecting diaphragmatic lesions in advanced ovarian cancer. However, hepatic mobilization potentially induces postoperative portal vein thrombosis and hepatic infarction. No reports exist regarding these postoperative complications of gynecological surgeries.

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Ovarian vein thrombosis in a postpartum female: A case report.

Radiol Case Rep

November 2024

Department of Internal Medicine, NAIHS, Kathmandu, Nepal.

Ovarian vein thrombosis (OVT), while uncommon, is a serious complication that can arise from pregnancy, pelvic inflammatory disease, oncological conditions, and pelvic surgeries. Here we discuss a case of a 37-year-old woman who, during her postpartum period, experienced lower abdominal pain and fever. Utilizing imaging findings, she was ultimately diagnosed with right ovarian vein thrombosis.

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Epidemiology, natural history, diagnosis, and management of ovarian vein thrombosis: a scoping review.

J Thromb Haemost

November 2024

National Institute of Healthcare and Medical Research, Acute and Chronic Cardiovascular Failure Unit and Nancy Regional University Hospital, Vascular Medicine Division and Regional Competence Center for Rare Auto-Immune Diseases, Université de Lorraine, Nancy, France. Electronic address:

Article Synopsis
  • Ovarian vein thrombosis (OVT) is a rare but serious condition that can happen after giving birth or in cancer patients.
  • Researchers looked at older studies to understand how OVT is treated and found that the average age for diagnosis is 37.
  • They discovered that special imaging tests like MRI are the best for diagnosing OVT, and the common treatment is using certain blood thinners for a few months.
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Plasma microRNA Environment Linked to Tissue Factor Pathway and Cancer-Associated Thrombosis: Prognostic Significance in Ovarian Cancer.

Biomolecules

July 2024

Molecular Oncology and Viral Pathology Group, Research Center of IPO Porto (CI-IPOP)/Pathology and Laboratory Medicine Dep., Clinical Pathology SV/RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Centre (Porto. CCC), 4200-072 Porto, Portugal.

Ovarian cancer (OC) is a leading cause of death among gynaecological malignancies. The haemostatic system, which controls blood flow and prevents clotting disorders, paradoxically drives OC progression while increasing the risk of venous thromboembolism (VTE). MicroRNAs (miRNAs) have emerged as crucial in understanding VTE pathogenesis.

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From Ovarian Hyperstimulation to the Discovery of a Liver Nodule.

Cureus

July 2024

Obstetrics and Gynecology, Unidade Local de Saúde (ULS) de Coimbra, Coimbra, PRT.

Article Synopsis
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Objective: To determine the incidence of venous thromboembolism in patients with advanced epithelial ovarian cancer undergoing neoadjuvant chemotherapy in UK gynecological cancer centers. Secondary outcomes included incidence and timing of venous thromboembolism since cancer presentation, impact on cancer treatment, and mortality.

Methods: All UK gynecological cancer centers were invited to participate in this multi-center retrospective audit through the British Gynecological Cancer Society.

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Comorbid thrombosis as an adverse prognostic factor in patients with ovarian clear cell carcinoma regardless of staging.

Int J Clin Oncol

September 2024

Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.

Objective: Patients with ovarian clear cell carcinoma (OCCC) often present with thrombosis. While cancer patients with concomitant thrombosis were generally reported to have worse prognoses than those without, the association between thrombosis and prognosis has not been elucidated in OCCC. This study aimed to determine how the co-occurrence of thrombosis affects OCCC prognoses.

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Article Synopsis
  • This study looked at how well precision nursing and special devices called IPC help prevent blood clots in ovarian cancer patients during and after surgery.
  • Researchers checked the records of 136 patients to see how they did with these different types of care and compared results like surgery time and blood loss.
  • The findings showed that the group receiving precision nursing and IPC had better results, with fewer blood clots and healthier blood tests compared to those who got regular care.
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Article Synopsis
  • This study compares a new laparoscopic technique for para-aortic lymphadenectomy, called the "tent-pitching" antegrade approach, to the traditional retrograde approach in gynecological cancer surgeries, assessing success rates, complications, and lymph node counts.
  • A retrospective review of 173 patients revealed that the antegrade method had higher success rates (97.5% vs. 68.82%), removed more lymph nodes (median of 14 vs. 7), and had fewer complications compared to the retrograde method.
  • Anatomical variations in the para-aortic region were noted in nearly 29% of patients, helping to highlight the importance of understanding vascular anatomy for surgical safety.
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Haemostatic Gene Expression in Cancer-Related Immunothrombosis: Contribution for Venous Thromboembolism and Ovarian Tumour Behaviour.

Cancers (Basel)

June 2024

Molecular Oncology and Viral Pathology Group, Research Center of IPO Porto (CI-IPOP)/Pathology and Laboratory Medicine Dep., Clinical Pathology SV/RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Centre (Porto. CCC), 4200-072 Porto, Portugal.

Ovarian cancer (OC) is the deadliest gynaecological malignancy. Identifying new prognostic biomarkers is an important research field. Haemostatic components together with leukocytes can drive cancer progression while increasing the susceptibility to venous thromboembolism (VTE) through immunothrombosis.

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Objectives: A pharmacoepidemiological study to assess VTE risk factors in a diabetes-rich population.

Methods: The study comprised 299,590 individuals. We observed 3450 VTEs and matched them with 15,875 controls using a nested case-control approach and collected data on comorbidities and prescriptions.

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Article Synopsis
  • - Cancer-associated thrombosis is a significant issue for cancer patients, ranking as the second leading cause of death, prompting a survey among MITO-MaNGO members to assess thromboembolic prophylaxis practices.
  • - The survey revealed that 82% of respondents recognize the importance of prophylaxis in gynecologic oncology, with most centers employing standardized protocols for patients undergoing surgery or chemotherapy.
  • - Despite this awareness, only 26% of respondents utilized a thromboembolic risk assessment scale, suggesting a gap in the application of preventative measures, particularly for outpatient settings.
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Septic pelvic thrombophlebitis (SPT) is a rare condition that forms thrombosis in the pelvic veins, typically the ovarian veins, with subsequent infection and inflammation. We present a case of right ovarian vein thrombosis (ROVT), methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, and delayed onset of SPT symptoms, requiring tissue-plasminogen activator. A 40-year-old woman, G3P2, at 38 weeks' gestation, was admitted with a fever of 39°C.

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Article Synopsis
  • In 2021, a multi-disciplinary group developed the Symptoms-Varices-Pathophysiology (SVP) classification system to effectively categorize patients with pelvic venous disorders (PeVD) due to limited data on existing tools.
  • A study conducted from January 2018 to January 2019 reviewed the medical records of 70 female patients treated for PeVD, assessing factors like age, race, intervention types, and their categorization under the SVP system.
  • Results showed the average patient age was 47.4, with a significant proportion exhibiting symptoms related to S2 disease, such as dyspareunia, and lower extremity varicosities were present in 35% of patients at the time of
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Successful management of postpartum venous thrombosis following splenectomy for traumatic splenic rupture: a case report.

J Int Med Res

May 2024

Department of Obstetrics and Gynaecology, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, Zhejiang Province, China.

Traumatic splenic rupture is rare in pregnant women; and multiple venous thromboses of the portal vein system, inferior vena cava and ovarian vein after caesarean section and splenectomy for splenic rupture has not been previously reported. This case report describes a case of multiple venous thromboses after caesarean section and splenectomy for traumatic splenic rupture in late pregnancy. A 34-year-old G3P1 female presented with abdominal trauma at 33 weeks of gestation.

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Pre-treatment thrombocytosis and ovarian cancer survival: A meta-analysis.

Eur J Obstet Gynecol Reprod Biol X

June 2024

First Department of Obstetrics and Gynaecology, Division of Gynaecologic Oncology, 'Alexandra' General Hospital, National and Kapodistrian University of Athens, Athens, Greece.

An association between thrombocytosis and cancer progression and decreased survival has been observed for various forms of cancer. The aim of this study was to evaluate the impact of pre-treatment thrombocytosis on ovarian cancer survival. Medline, Scopus, Clinicaltrials.

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Introduction: Chemotherapy is part and parcel of the multimodality approach to cancer treatment. Chemoports are frequently used to administer chemotherapy, preventing complications associated with the use of peripheral lines. However, chemoports have their own set of complications and can be very debilitating at times.

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Ovarian vein thrombus in a pediatric patient: A case study.

Am J Emerg Med

June 2024

Corewell Health West Medical Group, Helen DeVos Children's Hospital Emergency Department, Grand Rapids, MI, USA. Electronic address:

Acute abdominal pain is a very common chief complaint in the pediatric population, accounting for 5-10% of emergency department (ED) visits. Etiology differentiation is determined by complete history and physical examination, basic laboratory studies, and a variety of imaging study options. In this case report, we present an 8-year-old female with an unusual etiology of acute lower abdominal pain.

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