3,608 results match your criteria: "Otitis Externa"
Malignant otitis externa: What is the role of surgery?
Laryngoscope Investig Otolaryngol
December 2024
Division of Otology, Neurotology and Cranial Base Surgery, Department of Otolaryngology-Head and Neck Surgery The Ohio State University Wexner Medical Center Columbus Ohio USA.
Objective: Malignant otitis externa (MOE) is typically managed with long-term broad-spectrum antibiotics. The impact of surgical intervention on clinical outcomes is not well described. This study aims to compare clinical outcomes of MOE patients managed with or without surgery.
View Article and Find Full Text PDFCanine Malassezia dermatitis (CMD) and otitis externa are generally treated by antifungal drugs. However, azole-resistant strains have been isolated from canine skin and ear canals worldwide. Phytochemicals isolated from essential oils are effective alternatives for inhibiting Malassezia pachydermatis.
View Article and Find Full Text PDFC-reactive protein (CRP) and otorrhoea as prognosticate markers for necrotising otitis externa treatment response: based on a retrospective cohort study of 62 patients.
Acta Otolaryngol
December 2024
ENT Department, Queen's Medical Centre, Nottingham, UK.
Background: Recurrence rate of necrotising otitis externa (NOE) after treatment is 15-20%. This is mainly due to a lack of reliable clinical indicator for the resolution of disease.
Aims: We aim to assess the predictability of the otalgia, otorrhoea and C-reactive protein (CRP) levels in a large cohort of sixty-two patients for treatment outcome.
Approach to otitis externa in Australian general practice.
Aust J Gen Pract
December 2024
MBBS, FRACS, ENT Consultant, Surgical Treatment and Rehabilitation Service (STARS), Brisbane, Qld.
Background: Acute otitis externa (AOE) is an inflammatory condition of the outer ear seen in Australian general practice and is prevalent in tropical climates like North Queensland.
Objective: This article aims to delineate key facets of AOE, identify high-risk populations and propose a streamlined management approach aligned with the American Academy of Otolaryngology Head and Neck Surgery (AAO-HNS) guideline, emphasising the role of primary care in optimal patient care.
Discussion: Outlined within this article are key elements of AOE, from anatomy to risk factors, examination, diagnosis, differentials, management, prevention and indications for referral.
Skull base osteomyelitis: HBO as a therapeutic concept Effects on clinical and radiological results.
Eur Arch Otorhinolaryngol
November 2024
Department of Otorhinolaryngology, Duesseldorf University Hospital, Moorenstrasse 5, 40225, Duesseldorf, Germany.
Introduction: Skull base osteomyelitis is a rare but potentially life-threatening disease. It usually occurs as a complication of severe otitis externa or infection in the nasopharynx, often in immunocompromised patients. The therapeutic strategy is complex, patient-specific and requires interdisciplinary cooperation.
View Article and Find Full Text PDFPrevalence of bacterial ear infections and multidrug resistance patterns among ear infection suspected patients in Ethiopia: a systematic review and meta-analysis.
BMC Infect Dis
November 2024
Department of Medical Laboratory Science, College of Medicine and Health Sciences, Wollo University, P.O. Box: 1145, Dessie, Ethiopia.
Article Synopsis
- Otitis media is a significant middle ear inflammation affecting hearing and cognitive performance, especially in developing countries, driven by factors such as lack of vaccination and malnutrition.
- A systematic review and meta-analysis in Ethiopia compiled data from 70 studies, finding a pooled prevalence of bacterial ear infections at 73.39% and multidrug resistance at 72.45%.
- Major bacteria involved include Pseudomonas aeruginosa and Streptococcus pneumoniae, with significant variability in infection rates among different studies.
Challenges in Management of Uncommon Otologic Fungal Disease - a Case Series and Review of Literature.
Indian J Otolaryngol Head Neck Surg
December 2024
Department of Otolaryngology Head Neck Surgery, LSU Health Shreveport, 1501 Kings' Hwy, Shreveport, 71103 LA USA.
Article Synopsis
- The study aims to explore the difficulties involved in diagnosing and treating fungal infections of the ear.
- It included a case series and literature review, focusing on three patients at LSU Health Sciences Center with complex fungal otitis externa between November 2020 and November 2023.
- The findings highlight that diagnosing fungal ear infections is tricky due to their similar symptoms to more common infections, and patient factors (like uncontrolled diabetes) add to the complexity; successful treatment requires teamwork among various medical professionals and ongoing patient care.
To Study the Microbiological Florae in Patients of Acute Otitis Externa.
Indian J Otolaryngol Head Neck Surg
December 2024
Department of Medicine, Kalpana Chawala Medical College, Karnal, India.
Article Synopsis
- The study aimed to identify the types of bacteria causing acute otitis externa (AOE) and their antimicrobial sensitivities in patients from a tertiary care center in North India.
- Out of 66 patients, 50 samples tested positive for bacterial cultures, with gram-negative bacteria accounting for 60% and gram-positive for 40%, the most common being Pseudomonas aeruginosa (48%).
- The findings emphasized the importance of regularly assessing bacterial flora and antimicrobial resistance to ensure effective treatment for AOE, as bacteria showed varying susceptibilities to different antibiotics.
Effects of seasonal, geographical and demographic factors on otitis externa microbiota in Queensland, Australia.
Aust J Gen Pract
November 2024
FRACS, Consultant Ear, Nose, Throat Surgeon, Department of Ear, Nose and Throat Surgery, Royal Brisbane and Women@s Hospital, Brisbane, Qld.
Article Synopsis
- * A study in Queensland identified Pseudomonas aeruginosa as the most common pathogen (37.9%) in coastal regions, while Staphylococcus aureus was prevalent inland; children are less likely to have OE from fungal causes.
- * The findings suggest that coastal areas should use targeted treatment for Pseudomonas aeruginosa, and antifungal drops should be used cautiously in children due to their lower risk of fungal infections.
Fungal Malignant Otitis Externa: A Systematic Review.
Cureus
October 2024
2nd ENT Department, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, GRC.
Article Synopsis
- Malignant otitis externa (MOE) is a serious condition often linked to fungi, especially in people with weakened immune systems, prompting a review of fungal cases (FMOE) among patients.
- The study analyzed 10 articles covering 197 patients, mostly older adults (average age 65.9 years), highlighting that a significant number (78.7%) had conditions like diabetes or cancer.
- Most patients received conservative treatment focusing on antifungals like itraconazole, with a notable 4% mortality rate attributed to factors such as late diagnosis and cranial nerve issues, suggesting that early antifungal treatment could enhance patient outcomes.
Diffusion-Weighted Imaging Does Not Differentiate Between Bacterial and Fungal Skull Base Osteomyelitis.
Clin Otolaryngol
November 2024
Department of Otolaryngology, Christian Medical College, Vellore, India.
Article Synopsis
- The study evaluates the use of apparent diffusion coefficient (ADC) values in MRI to differentiate between fungal and bacterial skull base osteomyelitis (SBO).
- Researchers conducted a retrospective review of 142 SBO patients and found that the most common pathogens were Pseudomonas, Aspergillus, and Staphylococcus aureus.
- Despite noting a difference in the average ADC values between infected and normal tissues, the results showed no significant difference between the ADC values of bacterial and fungal SBO, highlighting the importance of early biopsies for accurate diagnosis.
Bacteriuria Among Type 2 Diabetes Mellitus Patients Attending Ejisu Government Hospital in the Ashanti Region, Ghana.
Int J Microbiol
October 2024
Department of Biochemistry and Biotechnology, Faculty of Biosciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Article Synopsis
- * The study involved 58 T2DM patients, showing that 15.5% had significant bacteriuria, primarily in those without prior UTI history or symptoms.
- * Results indicated high antibiotic resistance among isolated bacteria, particularly against co-trimoxazole and tetracycline, while being fully susceptible to amikacin and levofloxacin, highlighting the need for routine bacterial culture and sensitivity testing in T2DM patients.
Changes functional prediction of ear canal flora in chronic bacterial otitis externa.
Front Cell Infect Microbiol
November 2024
Department of Otolaryngology, Head and Neck Surgery, The First Affiliated Hospital, Hainan Medical University, Haikou, China.
Article Synopsis
- The study aimed to analyze the ear canal microflora in patients with chronic bacterial otitis externa compared to healthy individuals.
- Using 16S rRNA high-throughput sequencing, researchers collected and sequenced ear canal samples from 14 patients (CB group) and 14 healthy controls (H group).
- Results indicated that the CB group had significantly lower microflora diversity and richness, with notable differences in specific bacterial phyla and genera, as well as functional predictions suggesting potential links to amino acid biosynthesis and lower aerobic characteristics in the affected group.
Fungal dysbiosis following antibacterial monotherapy in canine otitis externa.
J Small Anim Pract
November 2024
Department of Clinical Sciences and Services, University of London, Hatfield, UK.
Article Synopsis
- The study aimed to investigate whether treating refractory bacterial otitis in dogs with specific topical antibiotics leads to an increase in yeast overgrowth, particularly Malassezia.
- Twenty-nine dogs were treated with either fluoroquinolone or a combination of piperacillin and tazobactam, and ear swabs were taken to measure bacterial and yeast levels before and after treatment.
- Results showed a significant reduction in bacterial infections after treatment, but a notable increase in yeast (especially in dogs treated with piperacillin/tazobactam), highlighting the importance of monitoring for yeast overgrowth during antibacterial treatment.
Successful surgical excision of periaortic hemangiosarcoma in a dog.
Can Vet J
November 2024
Surgery Department, Veterinary Referral Associates, 500 Perry Parkway, Gaithersburg, Maryland 20877, USA.
Article Synopsis
- - The report details the case of an 8-year-old male Siberian husky with an incidental diagnosis of a large caudal mediastinal mass discovered during a CT scan prior to surgery for ear issues.
- - The dog underwent successful surgical excision of the mass, which was later confirmed to be hemangiosarcoma through histopathology.
- - Despite the surgery, the owners chose not to pursue chemotherapy, and the dog was euthanized 86 days later due to a perceived decline in quality of life, marking the first documented successful surgical management of periaortic hemangiosarcoma.
infection-associated erythema multiforme in a Maltese dog.
Can Vet J
November 2024
Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea (Hyun); Ieul Animal Clinic, Seoul 06580, Republic of Korea (Hwang S-H); Laboratory of Veterinary Dermatology and the Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea (Hwang C-Y).
Article Synopsis
- - An 8-year-old spayed female Maltese dog was referred for treatment due to persistent, itchy, ulcerative skin lesions and chronic ear infections lasting four months.
- - A biopsy showed skin damage and a bacterial infection that was resistant to multiple drugs; treatment with ciprofloxacin led to improvement of the skin lesions.
- - The case suggests that infections may trigger erythema multiforme in dogs, which is a rare condition that's not well described in veterinary literature.
The association between acute otitis externa-related emergency department visits and extreme weather events in a temperate continental climate.
Int J Hyg Environ Health
October 2023
Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Vienna, Vienna, Austria.
Article Synopsis
- This study investigates the impact of extreme weather events, particularly high temperatures, on the occurrence of acute otitis externa (AOE), a common ear condition leading to emergency room visits.
- Analysis of 1522 AOE-related visits from 2015 to 2018 revealed a significant increase in cases following high-temperature days, showing a relative risk increase one day after such events.
- The study also found that both low and high humidity levels reduced immediate AOE-related visits, while higher precipitation and wind speeds were linked to fewer cases over several days.
Frequency Distribution of Pediatric Primary Care Cases in a Rural Site in The Philippines: A Cross-Sectional Study.
Acta Med Philipp
October 2024
Philippine Primary Care Studies, Center for Integrative and Development Studies, University of the Philippines Diliman.
Article Synopsis
Efficacy of 1.5% levofloxacin otic solution in treating acute otitis externa: A post hoc analysis of ENT103-3001, a multicenter randomized double-blind parallel-group placebo-controlled phase III study in otitis media with persistent otorrhea.
Auris Nasus Larynx
October 2024
Department of Otorhinolaryngology, Saitama Medical University Hospital, Saitama Medical University, 38 Morohongo Moroyama-machi, Iruma-gun, Saitama 350-0495, Japan. Electronic address:
Article Synopsis
- - The study analyzed the effectiveness of a 1.5% levofloxacin otic solution for treating acute otitis externa in patients with nonintact tympanic membranes who also had chronic and acute otitis media
- - Researchers evaluated digital endoscopic images to assess inflammatory findings and track patient improvements, comparing results between those treated with levofloxacin and a placebo group
- - Results showed that a significantly higher percentage of patients treated with levofloxacin experienced improvement in inflammatory symptoms (47.6%) and had high bacterial eradication rates (94.3%) compared to those on placebo.
Associations of heat with diseases and specific symptoms in Flanders, Belgium: An 8-year retrospective study of general practitioner registration data.
Environ Int
November 2024
Department of Public Health and Primary Care, KU Leuven, Kapucijnenvoer 33, Leuven, Flanders 3000, Belgium.
Article Synopsis
- Global temperature rise is a significant health issue, and previous research mainly relied on hospital data to assess its effects on health.
- This study focused on the relationship between ambient temperature and various heat-related medical conditions using data from general practitioners in Flanders, Belgium, collected over eight years (2012-2019).
- The results indicated a J-shaped association between heat and health outcomes, with higher risks for certain conditions like skin problems and urinary infections at elevated temperatures, particularly at minimum temperature thresholds.
Comparative performance of video-otoscopy and CT in the diagnosis of external ear disease in cats.
J Feline Med Surg
October 2024
Department of Morphology, Imaging, Orthopaedics, Rehabilitation and Nutrition, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Article Synopsis
- The study aimed to compare the effectiveness of CT scans and video-otoscopy in detecting masses in the external ear canal of cats, while also outlining the CT characteristics of feline ear diseases.
- Out of 32 examined ears, both methods successfully identified 13 external ear canal masses without any false positives, leading to perfect agreement in detecting these masses.
- However, there was little consistency between the two methods regarding other ear conditions like inflammation and structural changes, and external ear canal mineralization showed no link to the duration of clinical symptoms.
Article Synopsis
- The study aimed to investigate the causes, treatments, and complications of otitis externa (OE) by analyzing patient data from a university hospital over an eight-year period.
- Out of 269 patients with OE, complications such as otitis media and mastoiditis were noted, with certain risk factors like antibiotic use and systemic diseases being more prevalent in patients with mastoiditis.
- Effective treatment typically involves local care, but persistent infections may require systemic drugs; the study highlights the need for monitoring potential long-term hearing issues in affected patients.
Temporal Bone Myeloid Sarcoma Presenting as Necrotizing Otitis Externa: A Case Report and Literature Review.
Ear Nose Throat J
October 2024
Department of Otolaryngology-Head and Neck Surgery, Al-Mouwasat University Hospital, Faculty of Medicine, Damascus University, Damascus, Syria.
Article Synopsis
- - Myeloid sarcoma (MS) is an extramedullary growth of immature myeloid cells often found in association with acute myeloid leukemia (AML), typically occurring in lymph nodes, skin, and the head and neck area.
- - A case study is presented involving a 47-year-old woman who experienced various ear-related symptoms and was initially misdiagnosed, but later found to have MS in the temporal bone after further tests.
- - The paper highlights the importance of considering MS in AML patients with vague symptoms, outlines diagnostic methods like CT and MRI, and emphasizes that systemic chemotherapy is usually the best treatment, stressing the need for more research on this rare condition.
A Study of Hearing Acuity and the Health of the External Auditory Canal Among Earphone Users in Central India.
Cureus
September 2024
Obstetrics and Gynaecology, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.
Background and objective The pervasive use of earphones has raised concerns about its potential impact on hearing acuity and the health of the external auditory canal (EAC). This study aimed to investigate these effects in a sample of individuals in Central India to better understand the associated risks. Materials and methods This observational cross-sectional study was conducted in the Department of Otorhinolaryngology, Acharya Vinoba Bhave Rural Hospital, Sawangi Wardha.
View Article and Find Full Text PDF