1,018 results match your criteria: "Osmania Medical College.[Affiliation]"

Advancing Precision Rhinoplasty: Preoperative Digital 3D Surgical Planning.

Indian J Otolaryngol Head Neck Surg

October 2024

Department of Otorhinolaryngology, Government ENT Hospital, Osmania Medical College, Door No.5-1-174, Opposite State Bank of India Head Office, Bank Street Road, Koti, Hyderabad 500095 India.

Article Synopsis
  • * It involved thorough assessments, including medical history, blood tests, and high-resolution CT scans, alongside 3D reconstruction tools like 3D Slicer and Blender 3D, to analyze nasal anatomy.
  • * The findings suggest that 3D visualization improves surgical precision and results in better patient outcomes, reinforcing the importance of ethical practices in surgical planning.
View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on reconstructing soft tissue defects around the knee and upper leg using a proximally based sural artery flap, which provides a thin and stable skin cover.
  • Conducted on 10 male patients aged 20 to 65, the research found that trauma from road traffic accidents was the most common cause of these defects, with sizes varying up to 16x14 cm.
  • Results showed the flap technique effectively covered medium to large defects with minimal complications, offering reliable and durable soft tissue coverage without significant donor site issues.
View Article and Find Full Text PDF
Article Synopsis
  • Hydatid disease is a rare parasitic infection, especially in the head and neck region, and can lead to cystic formations that can cause various symptoms due to their size or rupture.
  • A 38-year-old male presented with recurrent ear issues and headaches, and imaging revealed cystic lesions affecting both the temporal bone and intracranial structures.
  • The patient underwent surgery and received medical treatment with Albendazole, resulting in a successful outcome as he remained asymptomatic one year post-surgery.
View Article and Find Full Text PDF

Advances in Recurrent Respiratory Papillomatosis Treatment: Adjuvant Intralesional Bevacizumab's Impact, Potential and Insights from a Case Series Study.

Indian J Otolaryngol Head Neck Surg

October 2024

Department of Otorhinolaryngology, Government ENT Hospital, Osmania Medical College, Door No.5-1-174, Opposite State Bank of India Head Office, Bank Street Road Koti, Hyderabad, 500095 India.

Article Synopsis
  • Recurrent respiratory papillomatosis is a benign but aggressive condition caused mainly by HPV types 6 and 11, leading to the formation of warts in the respiratory tract, particularly the larynx, necessitating multiple surgeries for management.
  • A study conducted on 13 patients aged 3 to 30 evaluated the effects of intralesional bevacizumab as an adjuvant therapy, which involved three injections over 12 weeks.
  • The results indicated that this treatment significantly extended the time between surgeries and reduced the total number of procedures needed each year, with no reported adverse effects, showing improvements in patient health as measured by the Derkay score.
View Article and Find Full Text PDF

State-of-Art Therapeutics in IgA Nephropathy.

Indian J Nephrol

June 2024

Department of Medicine, Division of Nephrology, University of Alabama, Birmingham, USA.

Article Synopsis
  • - Immunoglobulin-A nephropathy (IgAN) is the leading form of primary glomerulonephritis globally, with about 40% of patients eventually facing end-stage kidney disease (ESKD) within 30 years post-diagnosis due to immune complex formation caused by elevated Gd-IgA1 levels.
  • - Current management focuses on supportive care using medications like renin-angiotensin system inhibitors and sodium-glucose transporter inhibitors to help control proteinuria, with recent advances leading to approvals for new treatments like budesonide and sparsentan.
  • - Ongoing research is exploring novel therapies targeting different pathways involved in IgAN, including those affecting Gd-IgA1 production and the complement system,
View Article and Find Full Text PDF

Emicizumab in Children with Severe Hemophilia A.

Indian J Pediatr

September 2024

Department of Pediatrics, Institute of Child Health - Niloufer Hospital for Women and Children, Osmania Medical College, Hyderabad, Telangana, India.

Objectives: To assess the effectiveness and tolerability of emicizumab prophylaxis in hemophilia A (HA). Emicizumab is a novel therapeutic drug which is the first and only non-factor replacement agent licensed for use in people with HA.

Methods: Pediatric patients aged 1 mo to 12 y with severe HA and frequent / life threatening bleeding events, with or without coagulation protein factor VIII inhibitors were enrolled (n = 18) in this observational pre-post study.

View Article and Find Full Text PDF

Introduction In developing countries such as India, severe acute malnutrition (SAM) has been a cause for great concern in the pediatric population. SAM is associated with significant morbidity and mortality in children less than 60 months of age and leaves them vulnerable to diseases due to a decrease in immunological response. Children with SAM are prone to infections, and due to nutritional deficiency, many have anemia which may be a direct or indirect cause of morbidity and mortality.

View Article and Find Full Text PDF
Article Synopsis
  • Rheumatoid vasculitis (RV) is a rare but serious complication of rheumatoid arthritis that involves inflammation of small and medium-sized blood vessels.
  • A 34-year-old male with chronic alcoholism presented with symptoms like epigastric pain and joint swelling, initially raising concerns for different conditions before being diagnosed with RV.
  • The patient showed significant improvement after treatment with intravenous hydrocortisone, highlighting the importance of recognizing the potential for gastrointestinal involvement in RV and the need for early diagnosis and intervention in such cases.
View Article and Find Full Text PDF

Background: Caffeine products are increasingly found in a wide range of products that abuse of the substance may be unnoticed. Introduction of new energy drinks has led to an increase in consumption of caffeine in the last few decades. Caffeine is a cognitive booster and has physically enhancing effects, leading to its higher consumption across various age groups.

View Article and Find Full Text PDF
Article Synopsis
  • * Laboratory tests indicated he had acute kidney injury (AKI) along with low sodium, calcium, and potassium levels.
  • * A kidney biopsy showed significant damage and a genetic test confirmed Bartter syndrome, leading to treatment with IV hydration and supplements, resulting in recovery from AKI.
View Article and Find Full Text PDF

Background: Sexual dysfunction (SD) is a significant issue among psychiatric patients on psychotropic medications. This study aims to compare SD in patients using antipsychotics and antidepressants.

Objective: To evaluate the prevalence of SD and its effect on the quality of life among psychiatric patients on medications.

View Article and Find Full Text PDF

Paraduodenal hernias (PDH) are a type of internal hernia that results from errors in midgut rotation and failure of mesenteric fusion. Internal hernias themselves are a rare presentation that accounts for less than 1% of total hernias, and paraduodenal hernias contribute more than half of internal hernias. Left paraduodenal hernias (LPDH) occur more frequently as compared to right paraduodenal hernias.

View Article and Find Full Text PDF