Bullous Type 2 Lepra Reaction: A Rare and Significant Case Report.

Bullous type 2 lepra reactions are a rare initial presentation in leprosy that can complicate the disease with vesiculo-bullous lesions. Early recognition and differentiation from other bullous disorders are critical for timely corticosteroid and multidrug therapy initiation to improve patient outcomes.

Medially Based "Abdominal Rotation Advancement Flap": A Promising Technique for Mastectomy Defect Reconstruction in "High-Risk Patients" Awaiting Adjuvant Radiotherapy.

 Extensive postmastectomy defects and soft-tissue defects often require some additional flap cover of reconstruction after excision. The reconstruction aim in this group should be a diligent and easy closure with a quality skin cover, early recovery, and brief stay in hospital so that the patients can receive early postoperative radiotherapy/chemotherapy. Medially based abdominal transposition flap is a type C fasciocutaneous flap based on medial perforating vessels.

Acute hemorrhagic conjunctivitis outbreaks associated with Coxsackievirus A-24 in India, 2023.

Objective: Acute hemorrhagic conjunctivitis (AHC), commonly called pink eye, saw an alarming increase in incidence from July to September 2023 in different parts of India. Pink eye occurrences had reportedly increased three to four times more than in prior years, raising concerns among the community and healthcare professionals. This study aimed to identify the aetiological agent associated with AHC in 2023, genetically characterize the agent and describe the clinical presentation.

Functional Outcomes in the Distal End of Radius Fracture: A Prospective Study in a Tertiary Care Center.

Objectives: The objectives of this study are to determine the functional outcomes and compare them between conservative and surgical management in patients managed for closed-type intra-articular distal end of radius fractures.

Methods: A prospective observational study was done on 150 patients who underwent treatment for closed-type intra-articular distal end of radius fractures. As per Frykman Classification, they were type III.

Assessment of the Child-Pugh Score, Model for End-Stage Liver Disease Score, Fibrosis-4 Index, and AST to Platelet Ratio Index as Non-endoscopic Predictors of the Presence of Esophageal Varices and Variceal Bleeding in Chronic Liver Disease Patients.

Background Esophageal varices (EVs) develop as a complication of chronic liver disease and, when left unaddressed, can lead to variceal hemorrhage manifesting as severe hematemesis and occasionally, melena. Due to its frequent negative associations, early diagnosis and the implementation of non-selective beta blocker primary prophylaxis are imperative. Although upper gastrointestinal endoscopy has historically been used to image and identify EVs, patients frequently find this intrusive treatment to be uncomfortable and burdensome.

The High Burden of Asymptomatic Kidney Diseases in Individuals with HIV: A Prospective Study from a Tertiary Care Center in India.

Background: HIV infection is associated with a significant kidney disease burden. This study is aimed to screen for kidney disease in all HIV patients on highly active anti retroviral therapy (HAART), study clinico-histological correlation, and assess the impact of early diagnosis on the clinical course.

Materials And Methods: It was a prospective, longitudinal study done in a tertiary care hospital.

The Effectiveness of Cardiac Rehabilitation Programs in Improving Cardiovascular Outcomes: Systematic Review and Meta-Analysis.

Cardiovascular diseases (CVDs) are some of the most common conditions and the major contributors to death and disability globally, hence the need for proper secondary prevention interventions. Cardiac rehabilitation (CR) programs have been recognized as an essential component in the treatment of CVDs with the goal of decreasing the risk of new cardiovascular events and improving the quality of life. This systematic review and meta-analysis sought to determine the impact of CR as a form of CVD treatment on mortality, morbidity, functional capacity, and quality of life amongst the patient population.

Takayasu Arteritis Complicated by Superior Mesenteric Artery Stenosis and Bilateral Renal Arteritis: A Clinical Case Report.

Takayasu arteritis (TA), a rare large-vessel vasculitis, primarily affects women of childbearing age, causing granulomatous inflammation in the aorta and its major branches. This inflammation can lead to stenosis, aneurysms, or occlusion, with the abdominal aorta, subclavian, and brachial arteries commonly involved. We present the case of a 26-year-old female with TA with a rare involvement of the superior mesenteric artery (SMA).

Post-traumatic Epidermal Inclusion Cyst of the Index Finger: A Surgical Case Report.

Epidermoid cysts of the distal phalanx have rarely been reported in practice, although they are known to occur following penetrating trauma and pressure erosion. Notably, the distinction between epidermoid and dermoid cysts is unclear, with both terms being used interchangeably. However, epidermoid cysts are more commonly documented in the literature.

An Incidental Finding of Posterior Nutcracker Syndrome: A Case Report.

Posterior nutcracker syndrome (PNCS) is a rare vascular disorder involving the compression of the retro-aortic left renal vein between the aorta and the vertebral column. It often presents with left flank pain, hematuria, and varicocele. We report the case of a 39-year-old male who presented with diffuse abdominal pain, acute urinary retention, and left flank pain.

Ketamine Impact on Kidney Health.

Ketamine-induced uropathy (KIU) is a serious consequence of chronic ketamine abuse, presenting with complex renal and urinary symptoms. This study describes a 34-year-old female with a history of chronic ketamine abuse, resulting in stage 3 chronic kidney disease (CKD) and severe urological complications. Despite discontinuing ketamine use five years ago, she remains dependent on ureteral stents due to recurrent hydronephrosis and ureteral obstruction.

COVID-19 in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS): a propensity matched analysis (2020-2021).

Background: By 2023, COVID-19 had caused 6.8 million deaths in the United States. COVID-19 presents more severely in leukemia compared to solid tumors (OR 1.

Eccrine Spiradenoma of the Lower Back: A Surgical Case Report.

Spiradenoma is an uncommon benign neoplasm originating from eccrine sweat glands, typically characterized by a solitary tumor. Its diagnosis poses a challenge due to its morphological similarity to other solitary swellings. This report highlights the case of a 28-year-old male who presented with a solitary swelling on his right lower back.

The mystery of the hidden gallbladder: Navigating the unseen.

This case underscores the importance of advanced imaging techniques in diagnosing complex biliary anomalies. Accurate Magnetic Resonance Cholangiopancreatography and ultrasound evaluations can distinguish between choledochal cysts and duplicate gallbladders, guiding effective surgical intervention and improving patient outcomes.

Understanding the Relationship between the Ketogenic Diet and the Heart: A Novel Therapeutic Potential for Cardiovascular Health.

Obesity and cardiovascular diseases are major health problems worldwide, and weight loss is used as a treatment strategy to enhance various aspects. While there are many weight loss methods, one of the most effective is through a dietary approach. The ketogenic diet (KD), which is characterized by low carbohydrates and high levels of fat and/or protein, is used in obese patients as it is a promising treatment option for weight loss as well as for controlling the risk factors for cardiovascular diseases, as seen in its effects on cardio-metabolic outcomes, particularly in obesity, heart failure, and hypertension.