Factors of work environment hazardous for health in opinions of employees working underground in the 'Bogdanka' coal mine.

Introduction: Employees performing work underground in coal mines are exposed to the effect of many hazardous factors in their work environment which negatively affect their health.

Objective: The objective of the study was to recognize the opinions of employes working underground in one of the coal mines concerning the occurrence of factors hazardous for health in their work environment.

Material And Methods: The study was conducted in a group of 700 persons working underground in the 'Bogdanka' coal mine in Łęczna (Eastern Poland).

Scoping Global Aquaculture Occupational Safety and Health.

: In 2017 the Food and Agriculture Organization (FAO) Committee on Fisheries committed to prioritize occupational safety and health issues in aquaculture (AOSH). An international team was established to synthesize OSH knowledge concerning more than 19 million, often vulnerable, aquaculture workers found globally.: The study was conducted as a desktop scoping exercise using both peer-reviewed and gray literature and the knowledge and expertize of an international panel.

An investigation of instructional practices which promote occupational safety and health.

In order to promote insight into providing secure teaching and learning environments within schools, this study sought to: (a) explore instructional practices utilized by educators to promote occupational safety and health (OSH) and hearing protection within career and technical education programs; and (b) identify what barriers may exist which prevent instructors from teaching OSH and hearing protection. Utilizing a focus group methodology, this research examined automotive and diesel technology instructors within an eastern US state. Upon analysis, safety appears to be a priority for participants in this study.

[Correlations between parameters of central hemodynamics and cytokine profile in chronic kidney disease in combination with cerebrovascular diseases].

Aim: To study the relationship between central hemodynamics and arterial stiffness indicators with cystatin C, tumor necrosis factor-alpha (TNF-alpha) and interleukin-(IL)-10 in patients with chronic kidney disease (CKD) in combination with cerebrovascular diseases (CEV).

Material And Methods: One hundred and twenty patients, aged from 19 to 81 years, with signs of chronic renal dysfunction, including 73 with CKD (1st group) and 47 with CKD in combination with CEH (group 2), were examined. 'AngioScan' (Russia) was used to study indices of arterial rigidity.

Mechanistic insights into asymmetric transfer hydrogenation of pyruvic acid catalysed by chiral osmium complexes with formic acid assisted proton transfer.

A density functional theory study of the asymmetric transfer hydrogenation of pyruvic acid to ł- and d-lactic acids catalysed by a chiral osmium complex OsH[(R,R)TsNCH(Ph)CH(Ph)NH](η-p-cymene) reveals a formic acid assisted enantio-determining proton-coupled hydride transfer mechanism. Activation strain model analysis indicates that the C-H/π interaction between η-arene and carboxyl ligands has a significant influence on the enantioselectivity. The replacement of p-cymene by 4-isopropyl biphenyl or phenyl is highly likely to improve the catalytic performance of the complex.

Occupational Safety and Health in U.S. Aquaculture: A Review.

: Aquaculture encompasses a variety of species in both freshwater and marine settings and can combine elements of agriculture and fishing, two recognized hazardous occupations. Efforts are underway to expand the aquaculture sector in the United States (U.S.

Ergosterol Turnover in Yeast: An Interplay between Biosynthesis and Transport.

Sterols are important components of biological membranes that determine the physicochemical properties of lipid bilayer and regulate the functioning of membrane proteins. Being insoluble in water, sterols cannot diffuse between the membrane compartments separated by an aqueous phase. For this reason, distribution of sterols across cellular membranes is rather uneven.

Highlights from occupational safety and health continuing education needs assessment.

Background: There is a lack of trained Occupational Safety and Health (OSH) professionals able to meet the current and future demand for such expertize in the United States. Many OSH professionals are required to perform duties, which are outside of their primary area of expertize; thus, expansion of continuing education (CE) may be necessary to properly train individuals for new OSH responsibilities.

Methods: The National Institute for Occupational Safety and Health-funded Education and Research Centers collectively developed and distributed an internet-based survey to gauge the CE needs and interests of the OSH workforce.

Human biomonitoring in health risk assessment in Europe: Current practices and recommendations for the future.

Human biomonitoring (HBM) is an important tool to survey the internal exposure of humans which represents the real life chemical body burden to chemicals and/or their metabolites. It results from total exposure to chemical substances from different sources and via different routes. These substances may be regulated under different legislative frameworks on chemicals (e.

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.

Cyclic GMP-AMP synthase (cGAS) is the primary sensor for aberrant intracellular dsDNA producing the cyclic dinucleotide cGAMP, a second messenger initiating cytokine production in subsets of myeloid lineage cell types. Therefore, inhibition of the enzyme cGAS may act anti-inflammatory. Here we report the discovery of human-cGAS-specific small-molecule inhibitors by high-throughput screening and the targeted medicinal chemistry optimization for two molecular scaffolds.

[Bilateral impact of cardiorenal relationships in the nephrotic syndrome.].

To study and analyze the cardiorenal relationships in nephrotic syndrome, taking into account sex differences. A total of 272 patients with nephrotic syndrome (NS) aged 16 to 65 years were examined. All patients underwent general clinical examination, electro-and echocardiography, assessment of peripheral and biochemical blood counts.

Ovothiol A is the Main Antioxidant in Fish Lens.

Tissue protection from oxidative stress by antioxidants is of vital importance for cellular metabolism. The lens mostly consists of fiber cells lacking nuclei and organelles, having minimal metabolic activity; therefore, the defense of the lens tissue from the oxidative stress strongly relies on metabolites. Protein-free extracts from lenses and gills of freshwater fish, and , were subjected to analysis using high-field H NMR spectroscopy and HPLC with optical and high-resolution mass spectrometric detection.

Management of dyslipidaemia in patients with coronary heart disease: Results from the ESC-EORP EUROASPIRE V survey in 27 countries.

Background And Aims: One of the objectives of the ESC-EORP EUROASPIRE V survey is to determine how well European guidelines on the management of dyslipidaemias are implemented in coronary patients.

Methods: Standardized methods were used by trained technicians to collect information on 7824 patients from 130 centers in 27 countries, from the medical records and at a visit at least 6 months after hospitalization for a coronary event. All lipid measurements were performed in one central laboratory.

Prospective Evaluation of Fidelity, Impact and Sustainability of Participatory Workplace Health Teams in Skilled Nursing Facilities.

Organizational features of work often pose obstacles to workforce health, and a participatory change process may address those obstacles. In this research, an intervention program sought to integrate occupational safety and health (OSH) with health promotion (HP) in three skilled nursing facilities. Three facilities with pre-existing HP programs served as control sites.

Nutritional status following One Anastomosis Gastric Bypass.

Background & Aims: One Anastomosis Gastric Bypass (OAGB) has been accepted as an effective treatment for morbid obesity. However, data are scarce regarding nutritional implications of this procedure. Thus, our aim was to describe the health and nutritional status 12-20 months following OAGB surgery.

[Interleukins - 23, -12p40 as markers of neural tissue damage in neurosyphilis.].

To study the features of cytokines in patients with various forms of neurosyphilis. The complex laboratory examination of patients with neurosyphilis and syphilis without specific lesion of the nervous system was observed in the venereological department of the OSH "Clinical Dermatological and Venereological Dispensary" in Omsk in order to determine the concentration of interleukins - 23, 12p40 in CSF and assess their relationship with the course of syphilitic infection. The presence of regularities and features in the deviation of the immune status in the examined disease was established.

Workplace health promotion and safety in state and territorial health departments in the United States: a national mixed-methods study of activity, capacity, and growth opportunities.

Background: State and Territorial Health Departments (SHDs) have a unique role in protecting and promoting workers' health. This mixed-methods study presents the first systematic investigation of SHDs' activities and capacity in both Occupational Safety and Health (OSH) and Workplace Health Promotion (WHP) in the United States (US).

Methods: National survey of OSH and WHP practitioners from each of 56 SHDs, followed by in-depth interviews with a subset of survey respondents.

Essential Elements for Effective Safety and Health Education in Postsecondary Construction Career Technical Education.

Because Career Technical Education (CTE) programs at the community/technical college level are among the few places new construction workers receive training or preparation, they are an important vehicle for educating new and young workers about occupational health and safety (OSH). We developed recommendations for (1) OSH "core competencies" that all postsecondary construction students should achieve and (2) "essential elements" for OSH education in construction training programs. Based on a review of the literature, subject matter expert focus groups, and iterative engagement with an expert advisory group, we identified fourteen core competencies and a list of essential supporting elements at the school, program, and instructor levels.

[The gender features of disorders of composition of lipids of blood serum in patients with chronic pathology of kidneys.].

The purpose of the study was to investigate gender features of abnormalities of blood serum lipid composition and their relationship with clinical and functional manifestations in patients with chronic kidney disease (CKD). The study covered patients with CKD at pre-dialysis stage of disease, aged 17 - 71 years (average age 37.3±13.

[Renal dysfunction and indicators of arterial hormity in persons of elderly and senile age.].

In the presented paper had been examined parameters of arterial stiffness (stiffness index, SI m/s; reflection index, RI%; augmentation index, Alp; biological age of the vascular system, VA years; age index, AGI; alternative stiffness index, aSI; index of increase in HP=75, Aiр 75%), central arterial pressure and cystatin C content in serum. A totally were examined 98 persons (women, n=45 and men, n=53) elderly and older. A comparative analysis of arterial stiffness and its relationship with blood cystatin C in the examined groups with gender differences taken into account.

Spindle cell oncocytoma of the pituitary gland.

Objective: The authors report the diagnosis, management, and outcomes of 6 cases of spindle cell oncocytoma (SCO) in an effort to guide clinical diagnosis and management of these uncommon lesions.

Methods: This study is a retrospective review of cases involving adult patients who underwent resection of pituitary lesions at the authors' institutions between January 2000 and October 2017. The authors identified patients with histopathological confirmation of SCO and collected clinical data, including preoperative, perioperative, and postoperative management, complications, and outcomes.

Occupational Safety and Health of Foreign-Born, Latinx Dairy Workers in Colorado.

Objective: The US dairy industry, which employs foreign-born, primarily Latinx workers, has a two-fold higher injury rate than the national average. Little research has been conducted to understand the factors associated with the occupational safety and health (OSH) among foreign-born, Latinx dairy workers.

Methods: Structured interviews were conducted with 55 workers to assess a variety of OSH variables, including training experiences, health outcomes, and the psychosocial environment of the dairy.

Outreach to Low-Wage and Precarious Workers: Concept Mapping for Public Health Officers.

Objective: To explore concept mapping (CM) as a participatory methodology that can be used by public health officials to strategize approaches to reducing health inequities among low wage workers and workers with unstable employment.

Methods: In a workshop of 68 occupational health officers, mainly from government agencies, CM was demonstrated through gathering and prioritizing ideas for reaching underserved, at-risk working populations.

Results: Prior to the workshop, occupational health officers generated 99 brainstormed ideas on how to reach underserved workers.

RNA editing derived epitopes function as cancer antigens to elicit immune responses.

In addition to genomic mutations, RNA editing is another major mechanism creating sequence variations in proteins by introducing nucleotide changes in mRNA sequences. Deregulated RNA editing contributes to different types of human diseases, including cancers. Here we report that peptides generated as a consequence of RNA editing are indeed naturally presented by human leukocyte antigen (HLA) molecules.

Safety Talk and Safety Culture: Discursive Repertoires as Indicators of Workplace Safety and Health Practice and Readiness to Change.

Background: Small construction businesses (SCBs) account for a disproportionate share of occupational injuries, days lost, and fatalities in the US and other modern economies. Owner/managers of SCBs confront risks associated with their own and workers' safety and business survival, and their occupational safety and health (OSH) related values and practices are key drivers of safety and business outcomes. Given owner/mangers are the key to understanding and affecting change in smaller firms, as well as the pressing need for improved OSH in small firms particularly in construction, there is a critical need to better understand SCB owners' readiness to improve or adopt enhanced OSH activities in their business.