3,746 results match your criteria: "Osgood-Schlatter Disease"

Quantitative Analysis of Quadriceps Forces in Adolescent Females during Running with Infrapatellar Straps.

J Sports Sci Med

December 2024

Key Laboratory of Human Motion Analysis and Rehabilitation Technology of the Ministry of Civil Affairs, Beijing Advanced Innovation Centre for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.

Osgood-Schlatter disease (OSD) is caused by high, repetitive, and continuous traction exerted by the quadriceps on the tibial tuberosity, primarily occurring in adolescents. Infrapatellar straps are commonly recommended for its prevention and treatment, yet their impact on quadriceps forces in adolescents remains unstudied. Furthermore, current research on OSD predominantly focuses on adolescent males, with limited attention to adolescent females, despite similar incidence rates in both groups.

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  • - The use of recombinant human growth hormone (GHT) in children has grown significantly, with applications expanding from just treating growth hormone deficiencies to a wider range of conditions, increasing threefold over the past 20 years.
  • - Despite its benefits, there are rising concerns about safety, especially orthopedic issues like carpal tunnel syndrome and various growth-related diseases, attributed to factors such as hormonal changes and rapid growth associated with GHT.
  • - The review emphasizes the need for careful monitoring and coordinated care among pediatricians, endocrinologists, and orthopedic surgeons to minimize risks, and suggests future research to better understand injury patterns and improve clinical guidelines for managing orthopedic injuries in children on GHT.
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: A prominent anterior tibial tuberosity (or tibial tubercle) can be seen in ongoing Osgood-Schlatter disease (OSD) in teenagers or as a sequela of OSD in adults. Current radiological methods do not provide a true anatomical assessment of the tibial tuberosity; therefore, we proposed and developed a Magnetic Resonance Imaging (MRI)-based method for measuring the anterior tibial tuberosity index, aiming to deal with the current lack of effective techniques for accurately assessing these particular morphologic features. : A retrospective study included 47 knees with tibial tuberosity measurements on both true sagittal MPR images of 3D proton density (PD)-weighted MRI sequences and lateral knee radiographs.

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Is an excessively high posterior tibial slope a predisposition to knee injuries in children? Systematic review of the literature.

Orthop Traumatol Surg Res

October 2024

Service d'Orthopédie et Traumatologie Pédiatrique, CHU Amiens-Picardie, 80054, Amiens Cedex 1, France; GRECO (Groupement de Recherche et d'Etudes en Chirurgie Robotisée), Amiens University Hospital and Jules Verne University of Picardie, Amiens, France.

Article Synopsis
  • * Out of 294 identified studies, 11 were included, which highlighted a significant correlation between elevated PTS and ACL injuries, showing an increase in PTS by 2.1° to 4.3° in affected patients compared to healthy individuals.
  • * The findings suggest that a high PTS may be linked to an increased risk of knee pathologies in children, necessitating careful consideration when assessing young athletes with ACL injuries.
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In the early 20 century, the term «selfish brain» appeared in scientific literature, around which theory was formed, finding its proof in the work of doctors and scientists. The basic principle of the theory is that the superior hierarchy of the brain, whose needs are prioritized, results in the primary satisfaction of one's own needs, often to the detriment of the functioning of other organs and systems. The origins of the theory of «selfish brain», according to researchers, lie in the work of neurosurgery pioneer Harvey Cushing, who discovered a reflex named after him and consisting in increasing arterial pressure at high intracranial pressure.

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Freiberg disease (FD) is a condition characterized by osteochondrosis affecting the metatarsal heads, with the second metatarsal head being the most commonly affected. Dorsiflexion Closing Wedge Osteotomy of the Metatarsal Head (DCWMO) has been conventionally employed, whereas Osteochondral Autologous Transplantation (OAT) represents a more recent technique with restricted comparative research. This study aimed to compare the outcomes of DCWMO and OAT for treating Freiberg disease (FD).

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The effect of Scheuermann's kyphosis on rib cage morphology: A skeletal study.

Ann Anat

January 2025

Department of Anatomy and Anthropology, Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel; The Dan David Center for Human Evolution and Biohistory Research, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Background: Evolutionary changes in human rib cage morphology rendered it prone to pathologies like Scheuermann's kyphosis (SK). However, the impact of SK on rib cage morphology is unclear.

Purpose: This study aimed to examine differences in rib cage morphology (e.

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  • Equine osteochondrosis and osteochondral fragments in the fetlock joint are associated with environmental and genetic factors, leading to a scoping review to highlight knowledge gaps and research challenges in this area.
  • The review analyzes genetic factors and presents an overview of identified quantitative trait loci and candidate genes related to these disorders, following an initial part covering environmental influences.
  • The article discusses barriers to effective phenotypic and genomic selection, such as phenotyping difficulties and publication bias, emphasizing the need for standardized definitions and larger study populations to improve future research efforts.
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  • Short-term self-reported changes in symptom severity for musculoskeletal disorders may predict long-term recovery better than initial patient characteristics.
  • The study focused on adolescents aged 10 to 14 with knee pain (either patellofemoral pain or Osgood-Schlatter disease) and assessed self-management rehabilitation outcomes after 4 and 52 weeks.
  • Results showed that improvement after 4 weeks in patellofemoral pain patients was linked to better chances of further improvement at 52 weeks, while this was not the case for Osgood-Schlatter disease patients.
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: Osgood-Schlatter disease (OSD) belongs to the group of sterile bone necrosis and mainly affects athletically active children. The pathogenesis of OSD is currently not fully understood, so the purpose of this study was to evaluate the concentrations of selected matrix metalloproteinases (MMPs)-MMP-2, MMP-3, MMP-7, MMP-9, MMP-10 and MMP-26 in patients diagnosed with OSD compared to patients with diseases other than sterile bone necrosis : The study group included 140 patients with OSD, while the control group contained 100 patients with knee pain unrelated to sterile bone necrosis. The MMPs tested were determined by an enzyme-linked immunosorbent assay in plasma.

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  • * A retrospective CT scan study on 324 dogs found that 21% had presumed EPJF and another 21% had annulus fibrosus rupture (AFF), which were often located at the last lumbar vertebra’s caudal endplate.
  • * The study indicates that EPJF is linked to more severe IVDH grades and factors like age and certain spinal conditions, suggesting a need for further research to clarify its clinical significance and relationship to other spinal issues.
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  • * The study examined 266 young horses in Wallonia for correlations between conformation traits (foot and fetlock angles and height at withers) and the presence of these fragments, utilizing radiographic screenings.
  • * Key findings showed significant links between specific foot angles and fragment presence, including a notable palmar angle correlation, while an optimal cut-off for predicting fragment presence based on height at withers and bone diameter was established.
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Ultrasonographic assessment of equine metacarpal cartilage thickness is more accurate than computed tomographic arthrography.

Vet Radiol Ultrasound

January 2025

Comparative Orthopedic Research Laboratory, Department of Clinical Sciences, Faculté de Médecine Vétérinaire, Université de Montréal, St. Hyacinthe, Quebec, Canada.

Article Synopsis
  • - Articular cartilage in horses can be effectively imaged using ultrasonography, especially in cases of osteochondrosis, which affects common areas like the fetlock.
  • - A study measuring cartilage thickness in young horses found that ultrasonography had better accuracy compared to computed tomographic arthrography (CTA), with the best results at the distal sagittal ridge of the third metacarpal bone.
  • - While there was overall weak agreement between ultrasonography and histology, the findings indicated that cartilage thickness decreases with age, emphasizing the usefulness of ultrasonography for assessing cartilage in young horses.
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  • - The review consolidates research on Sinding-Larsen-Johansson disease (SLJD), focusing on its causes, diagnosis, imaging, and conservative treatment methods while highlighting gaps in the literature.! - Findings suggest SLJD typically affects active adolescents, especially males, presenting as knee pain, with ultrasound and MRI being the most reliable diagnostic tools. Conservative treatment strategies often lead to improvement within two to eight months.! - The authors recommend various conservative treatments including rest, cryotherapy, mobilization, isometric exercises, and NSAIDs, while calling for more cohort studies to enhance the management of SLJD.
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Environmental factors of equine osteochondrosis and fetlock osteochondral fragments: A scoping review - Part 1.

Vet J

December 2024

Department of Large Animal Surgery, Anaesthesia and Orthopaedics, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke 9820, Belgium.

Article Synopsis
  • A scoping review was conducted to connect environmental and genetic factors to equine osteochondrosis and osteochondral fragments in the fetlock joint, with the first part focusing on environmental aspects.
  • The review utilized databases like PubMed and Web of Science to identify 212 relevant studies after filtering and screening for eligibility.
  • The article discusses various environmental factors contributing to these disorders, including foetal programming, biomechanical trauma, nutrition, and emphasizes the need for multidisciplinary research to better understand these complex relationships for improved equine health management.
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  • Knee pain is a common issue among 13-year-olds, with a prevalence of 8% and a high rate of chronic cases (92.3% lasting over 3 months).
  • Most knee pain occurs on the front of the knee, with 37.5% of affected children experiencing pain daily.
  • Children with knee pain tend to have higher body mass indexes, and structural abnormalities like Osgood-Schlatter disease and bipartite patella were more frequently observed in them via MRI.
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  • Lower limb apophyseal injuries are common in children and adolescents, potentially impacting their quality of life and leading to reduced sports participation during important developmental years.
  • The research developed self-administered screening tools for two prevalent conditions: Sever's disease (calcaneal apophysitis) and Osgood-Schlatter's disease (tibial tuberosity apophysitis), using expert consensus and literature support.
  • The tools demonstrated high diagnostic accuracy, with potential to assist clinicians in preclinical screening and facilitate larger epidemiological studies to better understand the prevalence of these injuries.
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  • The study addresses the need for effective procedures to reconstruct osteochondral defects in femoral condyles, focusing on the biomechanical evaluation of tibiofemoral joint contact characteristics.
  • Eight cadaveric knees were tested under various conditions (intact, defects, and repairs) to measure tibiofemoral contact areas, forces, and pressures at different knee flexion angles and loads, using innovative reconstruction techniques.
  • Results showed that repairing medial and lateral condylar defects restored mean contact pressures to levels comparable to intact conditions, indicating the effectiveness of the new hybrid reconstructive procedure.
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  • * The most common issue identified was bone marrow edema, seen in 7.3% of the participants, while other conditions like Osgood-Schlatter disease and nonossifying fibromas were also noted.
  • * Results indicated certain associations between participant characteristics (such as sex and body weight) and the presence of these abnormalities, with boys showing higher rates of bone marrow edema.
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  • Osgood Schlatter's disease (OSD) is a common condition in adolescent athletes that causes pain at the tibial tuberosity during knee-loading activities; this study aimed to compare clinical and ultrasound characteristics in adolescents with OSD versus controls.
  • The study involved 35 adolescents with OSD and 21 matched controls, who performed various physical activities while rating their pain; results showed that OSD participants experienced higher pain levels and had notable differences in tendon thickness and Doppler signals compared to controls.
  • The most painful activity for those with OSD was the single-leg squat, particularly affecting the tibial tuberosity and patellar tendon, suggesting that these adolescents should be careful with certain movements that might worsen their pain.
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  • The tibial tuberosity consists of two parts: a superficial area with a patellar tendon and a deeper area of uncalcified cartilage; reduced calcification can lead to Osgood-Schlatter disease.
  • A study involving 20 male Wistar rats examined how decreased mechanical stimulation (via hind-limb suspension) affected the structure and calcification of the tibial tuberosity compared to a control group, revealing significant differences in tissue maturity.
  • Results indicated that reduced load on the tibial tuberosity led to pathological changes and calcification, underscoring the need for adequate mechanical stimulation through exercise to maintain healthy bone and joint structures.
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  • A randomized controlled trial tested a mix of nutritional supplements (including collagen type II, hyaluronic acid, and vitamin C) for managing lumbar osteochondrosis, a type of disc degeneration.
  • Fifty patients were split into supplement and placebo groups, and various patient-reported outcome measures (PROMs) were used to assess effectiveness over three months.
  • While overall PROMs showed no significant differences between groups, MRI results indicated better disc volume changes in the supplement group, suggesting potential benefits from the nutraceutical mix despite no major changes in patient-reported outcomes.
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[Non-traumatic osteochondral lesions of the knee joint during growth : Juvenile osteochondritis dissecans (JOCD) of the knee].

Orthopadie (Heidelb)

September 2024

Kinderorthopädie, Klinik für Unfallchirurgie, Orthopädie und Plastische Chirurgie, Universitätsmedizin Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Deutschland.

Article Synopsis
  • Juvenile osteochondritis dissecans is the most common knee osteochondral issue in kids aged 10 to 14, usually due to repeated stress injuries from sports.
  • The condition involves a bone lesion in the knee, typically on the inner part of the femur, and is influenced by factors like genetics and vitamin D levels.
  • Treatment varies: stable lesions can heal with rest and avoiding activities, while unstable ones may require surgery to repair the joint and prevent arthritis later on.
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