17,277 results match your criteria: "Oregon Health And Science University.[Affiliation]"
Adjunctive Middle Meningeal Artery Embolization for Subdural Hematoma.
N Engl J Med
November 2024
From the Departments of Neurosurgery (J.M.D., A.H.S.), Biomedical Informatics (J.M.D.), and Radiology (A.H.S.), Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, the Department of Neurological Surgery, New York Presbyterian Hospital-Weill Cornell Medical Center (J.K.), and the Department of Neurosurgery, Icahn School of Medicine at Mount Sinai (C.P.K.), New York, the Department of Neurosurgery, North Shore University Hospital at Northwell Health, Great Neck (T.W.L.), the Department of Neurosurgery, Albany Medical Center, Albany (A.R.P.), and the Department of Neurosurgery, Westchester Medical Center at New York Medical College, Valhalla (J. Santarelli) - all in New York; the Department of Neurosurgery and Brain Repair, University of South Florida, and Tampa General Hospital, Tampa (M.M.), Lyerly Neurosurgery, Baptist Medical Center Jacksonville, Jacksonville (R.A.H.), the Orlando Health Neuroscience Institute, Division of Neurosurgery, Orlando Health, Orlando Regional Medical Center, Orlando (M.C.C.), and the Department of Neurosurgery, University of Florida, Gainesville (M.J.K.) - all in Florida; the Department of Neuroscience, Valley Baptist Medical Center, and the Department of Neurology, University of Texas Rio Grande Valley, Harlingen (A.E.H.), the Department of Neurosurgery, Memorial Hermann-Texas Medical Center, Houston (P.R.C.), and the Department of Neurosurgery, Baylor Scott and White Health, Temple (W.S.L.) - all in Texas; the Departments of Neurosurgery and Engineering Science and Mechanics, Penn State University, Hershey (R.E.H.), the Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh (B.A.G.), and the Department of Neurosurgery, Geisinger and Geisinger Commonwealth School of Medicine, Wilkes-Barre (C.M.S.) - all in Pennsylvania; the Departments of Neurological Surgery, Surgery, Radiology, and Neurosciences, University of California, San Diego, La Jolla (A.K.), the Departments of Radiology (J.T.) and Neurosurgery (W.S.), Providence Little Company of Mary Medical Center, Torrance, Pacific Neuroscience Institute, Santa Monica (J.T., W.S.), and the Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles (W.J.M.) - all in California; the Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (J.F.); the Department of Neurosurgery, University of Utah School of Medicine, Salt Lake City (R.G.); the Cerebrovascular Center, Cleveland Clinic, Cleveland (M.B.), the Department of Neurology, ProMedica Toledo Hospital-University of Toledo College of Medicine and Life Sciences, Toledo (M.J.), and Wexner Medical Center, Ohio State University, Columbus (P.Y.) - all in Ohio; the Department of Neurosurgery, Rush University, Chicago (R.W.C.), and the Department of Neurosciences, Advocate Lutheran General Hospital, Park Ridge (J.B.) - both in Illinois; the Departments of Neurological Surgery, Neurology, Radiology, Otolaryngology, and Neuroscience, University of Kentucky, Lexington (J.F.F.); the Departments of Neurological Surgery, Radiology, Neurology, and Mechanical Engineering and the Stroke and Applied Neuroscience Center, University of Washington, Seattle (M.R.L.); the Department of Neurosurgery, Atrium Health Carolinas Medical Center, and Carolina Neurosurgery and Spine Associates - both in Charlotte, NC (J.D.B.); the Department of Diagnostic Radiology and Neuroradiology, Prisma Health Southeastern Neurosurgical and Spine Institute, Greenville, SC (M.I.C.); the Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City (H.J.S.); the Departments of Neurosurgery and Radiology, University of Alabama School of Medicine, Birmingham (J.J.); the Departments of Neurosurgery, Radiology, and Neurology, Washington University in St. Louis, St. Louis (J.W.O.); the Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City (K.D.); the Department of Neurosurgery, Emory University School of Medicine, Atlanta (J.A.G.); the Department of Neurointerventional Radiology, Goodman Campbell Brain and Spine, Indianapolis (D.H.S.); the Department of Neurosurgery, Michigan State University College of Human Medicine, Grand Rapids (J.S.), the Department of Neurology, McLaren Flint Hospital, Flint (A.Q.M.), and McLaren Macomb Hospital, Mount Clemens (A.Q.M.) - all in Michigan; the Department of Neurological Surgery, Oregon Health and Science University, Portland (J.J.L.); Aurora Neuroscience Innovation Institute, Milwaukee (T.W.); the Division of Neurointerventional Radiology, Department of Radiology, Beth Israel Lahey Health, Lahey Hospital and Medical Center, Burlington, MA (N.V.P.); and the Department of Neurosurgery, University of Colorado, Denver (C.R.).
Background: Subacute and chronic subdural hematomas are common and frequently recur after surgical evacuation. The effect of adjunctive middle meningeal artery embolization on the risk of reoperation remains unclear.
Methods: In a prospective, multicenter, interventional, adaptive-design trial, we randomly assigned patients with symptomatic subacute or chronic subdural hematoma with an indication for surgical evacuation to undergo middle meningeal artery embolization plus surgery (treatment group) or surgery alone (control group).
Cannabis and the overdose crisis among US adolescents.
Am J Addict
November 2024
International Academy on the Science and Impact of Cannabis-IASIC; Volunteer Faculty Member, University of Colorado Medical School, Colorado Springs, Colorado, USA.
Background And Objectives: Since 2019, the drug overdose death rate among adolescents 14-18 years of age in the United States more than doubled. That cannabis legalization may have contributed to this tragedy is investigated by comparing the death rate in jurisdictions that have legalized medicinal or both medicinal and recreational use with those that have not.
Methods: Unintentional drug overdose death data for each state and District of Columbia (jurisdictions) were obtained from CDC WONDER and separately evaluated according to the jurisdiction legalization implementation of cannabis: recreational legalization, medicinal legalization but not recreational legalization, and nonlegalization.
Fragile promise of psychedelics in psychiatry.
BMJ
November 2024
University of Rennes, CHU Rennes, Inserm, EHESP, Irset, Centre d'investigation clinique de Rennes, Rennes, France.
The biological effects of copper alloying in Zn-based biodegradable arterial implants.
Biomater Adv
February 2025
Department of Biomedical Engineering, Michigan Technological University, Houghton, MI 49931, USA.
Biodegradable metals based on zinc are being developed to serve as temporary arterial scaffolding. Although the inclusion of copper is becoming more prevalent for grain refinement in zinc alloys, the biological activity of the copper component has not been well investigated. Here, two ZnCu alloys (0.
View Article and Find Full Text PDFComparative efficacy of awake and asleep motor mapping in glioma surgery: A meta-analysis of 3011 patients.
Neurosurg Rev
November 2024
Department of Neurological Surgery, Oregon Health and Science University, Portland, USA.
Standard of care in glioma surgery involves maximal-safe resection. Intraoperative stimulation mapping can improve the extent of resection in eloquent area tumors. Resection is performed during awake craniotomy (AC) or under general anesthesia (GA).
View Article and Find Full Text PDFExperiences with One-to-One Trauma Center Trauma-Sensitive Yoga Sessions: Consensual Qualitative Research.
Int J Yoga Therap
November 2024
Associate Professor, Clinical Counseling Track, Department of Psychology, University of Minnesota, Duluth; and Director, Mind-Body Trauma Care Lab, Duluth, Minn.
Article Synopsis
- Trauma Center Trauma-Sensitive Yoga (TCTSY) is a therapeutic yoga intervention beneficial for those with PTSD, with this study specifically exploring one-on-one sessions instead of group formats.
- The study aimed to gather insights on participants' experiences and preferences, revealing they felt safer and more comfortable in individual sessions and reported positive impacts on their healing journey.
- Results suggest that participants experienced both physical and psychological benefits from TCTSY and expressed a strong desire to continue practicing, highlighting the potential for one-on-one trauma-informed care in healing.
Exploring the Link Between Early Technology Exposure and Developmental Milestones in Childhood.
Cureus
October 2024
Medical Education, Kirk Kerkorian School of Medicine at University of Nevada, Las Vegas (UNLV), Las Vegas, USA.
Background This study examined the relationship between touchscreen exposure and developmental outcomes in early childhood using the Ages and Stages Questionnaire, Third Edition (ASQ-3), a widely-used developmental screening tool. Methods During a well-child visit, parents of 51 children aged 18-36 months completed the ASQ-3 and a survey on their child's touchscreen habits (timing of introduction, daily usage duration, independent use, engagement in creative activities). Medical records were reviewed for developmental diagnoses and health conditions.
View Article and Find Full Text PDFEnteral tube administration of extemporaneously compounded suspensions of venetoclax according to an institutional medication use process.
J Oncol Pharm Pract
November 2024
Oregon Health and Science University Hospital and Clinics, Portland, OR, USA.
Introduction: Venetoclax is a potent oral oncology drug (OOD) frequently used to treat hematologic cancers due to its convenience and high efficacy. However, some patients cannot tolerate solid oral formulations, requiring a reformulated version of venetoclax for effective administration. Currently, there is limited information in the literature regarding the extemporaneous compounding of venetoclax.
View Article and Find Full Text PDFInternet use and health literacy among pediatric chronic kidney disease patients and their caregivers.
J Nephrol
December 2024
Department of Pediatrics, Oregon Health and Science University, Portland, OR, USA.
Background: Management of pediatric chronic kidney disease (CKD) is complex for affected youth and their families. Treatment requires a high level of family engagement to successfully manage medical appointments, inpatient hospital stays, and daily medication regimens. Health literacy has been identified as a possible contributor to health inequities and unsuccessful chronic disease management.
View Article and Find Full Text PDFPosition paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults.
Intensive Care Med
December 2024
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Article Synopsis
- The text discusses the occurrence of dual circulation during venoarterial extracorporeal membrane oxygenation (VA-ECMO), where blood from the body and an artificial heart/lung system mix, resulting in differing oxygen and carbon dioxide levels in two separate circulations.
- This phenomenon arises when native blood flow from the heart meets retrograde blood flow from the artificial system, creating distinct physiological environments on either side of the mixing point.
- The authors aim to clarify the terminology surrounding this issue to improve communication and clinical management for patients undergoing VA-ECMO treatment.
Local wound care management for pyoderma gangrenosum.
Int Wound J
November 2024
Department of Dermatology, Oregon Health and Science University, Portland, Oregon, USA.
Pyoderma gangrenosum (PG) is a rare, painful neutrophilic dermatosis characterized by rapidly progressing skin ulcers. Despite the importance of local wound care in managing PG, there is no consensus or evidence-based guidelines. This systematic review aimed to investigate local wound care strategies for PG.
View Article and Find Full Text PDFFrom the pages of AllergyWatch.
Ann Allergy Asthma Immunol
November 2024
University of California San Francisco, San Francisco, California.
Healing a gap in medical education: Efficacy of a wound care didactic intervention.
J Am Acad Dermatol
November 2024
Department of Dermatology, Oregon Health and Science University, Portland, Oregon. Electronic address:
Thalamic integration of basal ganglia and cerebellar circuits during motor learning.
bioRxiv
November 2024
Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA.
The ability to control movement and learn new motor skills is one of the fundamental functions of the brain. The basal ganglia (BG) and the cerebellum (CB) are two key brain regions involved in controlling movement, and neuronal plasticity within these two regions is crucial for acquiring new motor skills. However, how these regions interact to produce a cohesive unified motor output remains elusive.
View Article and Find Full Text PDFSafety and efficacy of pembrolizumab, radiation therapy, and surgery versus radiation therapy and surgery for stage III soft tissue sarcoma of the extremity (SU2C-SARC032): an open-label, randomised clinical trial.
Lancet
November 2024
Department of Radiation Oncology, Duke University, Durham, NC, USA; Duke Cancer Institute, Durham, NC, USA; Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada. Electronic address:
Background: Approximately half of patients with localised, high-risk soft tissue sarcoma of the extremity develop metastases. We aimed to assess whether the addition of pembrolizumab to preoperative radiotherapy and surgery would improve disease-free survival.
Methods: We completed an open-label, randomised clinical trial in patients with grade 2 or 3, stage III undifferentiated pleomorphic sarcoma or dedifferentiated or pleomorphic liposarcoma of the extremity and limb girdle.
Shock prediction with dipeptidyl peptidase-3 and renin (SPiDeR) in hypoxemic patients with COVID-19.
J Crit Care
February 2025
Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Background: Plasma dipeptidyl peptidase-3 (DPP3) and renin levels are associated with organ dysfunction and mortality. However, whether these biomarkers are associated with the subsequent onset of shock in at-risk patients is unknown.
Methods: Using plasma samples collected from participants enrolled in the fourth Accelerating COVID-19 Therapeutic Interventions and Vaccines Host Tissue platform trial, we measured DPP3 and renin in 184 subjects hospitalized with acute hypoxemia from COVID-19 without baseline vasopressor requirement.
Article Synopsis
- Atopic dermatitis (AD) significantly affects patients' quality of life, causing itching, skin pain, and sleep disturbances; ruxolitinib cream has shown effectiveness in treating these symptoms in adults and adolescents through two phase III clinical trials.
- In the TRuE-AD studies, patients applied different strengths of ruxolitinib cream or a vehicle cream, with results indicating that those using ruxolitinib experienced quick relief from symptoms like skin pain and sleep issues within hours or weeks of application.
- Analysis of patient-reported outcomes revealed notable improvements in overall quality of life and symptom burden after two weeks of using ruxolitinib cream compared to the vehicle, with sustained benefits observed throughout the study periods.
Caregivers in implantable brain-computer interface research: a scoping review.
Front Hum Neurosci
October 2024
Department of Philosophy, University of Washington, Seattle, WA, United States.
Introduction: While the ethical significance of caregivers in neurological research has increasingly been recognized, the role of caregivers in brain-computer interface (BCI) research has received relatively less attention.
Objectives: This report investigates the extent to which caregivers are mentioned in publications describing implantable BCI (iBCI) research for individuals with motor dysfunction, communication impairment, and blindness.
Methods: The scoping review was conducted in June 2024 using the PubMed and Web of Science bibliographic databases.
Middle Meningeal Artery Embolization for Subdural Hematoma.
Neurosurg Clin N Am
January 2025
Department of Neurosurgery, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA. Electronic address:
Article Synopsis
- Chronic subdural hematoma (cSDH) is becoming increasingly common and often requires surgical intervention to relieve symptoms, but drainage alone may lead to high recurrence rates.
- New techniques like middle meningeal artery embolization (MMAE) show promise in reducing these recurrence risks but raise questions about their integration into standard care.
- This review examines current cSDH management practices and explores the potential and uncertainties surrounding the use of MMAE.
"Mr. Smith Has No Mealtimes": Minimal Comfort Feeding for Patients with Advanced Dementia.
J Pain Symptom Manage
February 2025
Departments of Medicine, Psychiatry, Medical Humanities and Nursing, University of Rochester School of Medicine (T.E.Q.), Rochester, New York, USA.
While Comfort Feeding Only is appropriate for patients with advanced dementia, its emphasis on assiduous hand-feeding that may prolong life for years fails to accommodate the preferences of those who do not want to continue living with this illness. Some have proposed advance directives to completely halt the provision of oral nutrition and hydration once a person has reached an advanced stage of dementia. However, these directives may fail to address patients' discomfort, caregivers' obligations, or current care and regulatory standards when patients reside in facilities.
View Article and Find Full Text PDFLeaving the Patella Unresurfaced Does Not Increase the Risk of Short-Term Revision Following Total Knee Arthroplasty: An Analysis from the American Joint Replacement Registry.
J Knee Surg
December 2024
Department of Orthopaedic Surgery, The John Hopkins University, Baltimore, Maryland.
The benefit of patellar resurfacing in total knee arthroplasty (TKA) remains uncertain, with conflicting evidence regarding associated revision rates and clinical outcomes. Although initial studies have reported higher revision rates associated with unresurfaced patellae, recent evidence questions the necessity of routine patellar resurfacing. This study aimed to evaluate the risk of revision following TKA performed with and without patellar resurfacing using data from the American Joint Replacement Registry (AJRR).
View Article and Find Full Text PDF4DCT image artifact detection using deep learning.
Med Phys
November 2024
Biomedical Engineering, University of Iowa, Iowa City, Iowa, USA.
Article Synopsis
- Four-dimensional computed tomography (4DCT) is crucial for radiation therapy but can suffer from motion artifacts that hinder accurate imaging.
- A deep learning algorithm using a U-net convolutional neural network was created to identify various artifact types in 4DCT images, trained on over 23,000 slices from 98 scans.
- The model outperformed previous methods with a sensitivity of 78%, specificity of 99%, and an ROC AUC of 0.99, showing it can effectively detect multiple artifacts in a single image.
Lessons learned from the conduct of inpatient clinical trials in a pandemic.
J Clin Transl Sci
October 2024
Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institute of Health, Rockville, MD, USA.
Background: The COVID-19 pandemic amplified known challenges associated with the conduct of inpatient clinical trials, while also introducing new ones that needed to be addressed.
Methods: Stakeholders based in the United States who participated in the conduct of inpatient therapeutic trials for the treatment of COVID-19 as part of the Accelerating COVID-19 Therapeutic Interventions and Vaccines program identified challenges experienced in the conduct of these trials through a series of meeting to discuss and identify common themes. In addition, innovations developed to address these challenges and other potential solutions that may be utilized in future pandemics were highlighted.
Time-Driven, Activity-Based Cost Analysis of Pars Plana Vitrectomy in Rhegmatogenous Retinal Detachment at a Large Academic Center.
J Vitreoretin Dis
October 2024
Department of Ophthalmology and Visual Sciences, W.K. Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA.
Article Synopsis
- - The study performed a time-driven, activity-based cost analysis of retinal detachment surgery at a single academic institution to assess costs versus Medicare reimbursement rates.
- - The analysis revealed that the average cost of the surgery was $6,247.17 while the reimbursement was only $5,442.91, resulting in a net loss of $804.26 per procedure.
- - To break even, the average operation time would need to be significantly reduced from 90.49 minutes to 64.90 minutes, highlighting that current Medicare rates may underestimate true surgical costs and could impact patient access to care.
SHEA practice update: infection prevention and control (IPC) in residential facilities for pediatric patients and their families.
Infect Control Hosp Epidemiol
November 2024
Department of Pediatrics, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.
In 2011, the Society for Healthcare Epidemiology of America (SHEA) and Ronald McDonald House Charities® (RMHC®) established a formal collaboration to develop the first IPC guideline. Both organizations agreed that RMH programs staff and other organizations operating similar programs would benefit from a standardized approach. In 2023, the collaboration was re-established to revise and update the original IPC guideline.
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