Plant Based Extract Oil-Based Nano emulsions: Impact on Human Melanoma Cell Line.

Background: Cancer is a challenge for either the patient or the healthcare manager. Treatment protocols based on chemotherapy or radiotherapy, or both are interfering with the patient's life making him suffer rather than being alleviated. This burden pushed the scientists to search for new regimens that may help ameliorate patient as well as doctor inconvenience.

A Clinical Study Determining Pulp Vitality in Oropharyngeal Cancer Patients Undergoing Radiotherapy Using Diagnostic Tool-Pulse Oximetry.

Pulse oximetry is an equipment that evaluates pulp vitality for concrete endodontic diagnosis and treatment plan. One of the treatment methods of oropharyngeal cancer is radiotherapy. Radiotherapy has some harmful effects on dental pulp that affects pulp vitality.

Evaluation of Hematological profile in Oral Submucous Fibrosis: A Cross-sectional Study.

Aims: The purpose of this study was to estimate hemoglobin (Hb) level, red cell indices (RCIs), serum iron level and Vitamin B12 level in patients with oral submucous fibrosis (OSMF) and to analyze the association of these parameters in different stages of OSMF.

Setting And Design: This case-control study comprised of 65 individuals, with 40 OSMF patients and 25 controls. The OSMF patients were graded clinically according to the classification by Arakeri .

Quantitative Polymerase Chain Reaction Analysis of Cariogenic in Saliva of Oral and Laryngeal Cancer Patients Undergoing Radiotherapy: A Clinical Study.

Context: Radiotherapy leads to radiation-induced caries. There is limited knowledge about the quantification of cariogenic bacteria in the saliva of irradiated cancer patients.

Objective: The aim of this study is to check salivary pH, flow rate, and the assessment of in the saliva of irradiated oral and laryngeal cancer patients using quantitative real-time polymerase chain reaction (qRT-PCR).

Quantitative assessment of tumor-associated tissue eosinophilia and mast cells in tumor proper and lymph nodes of oral squamous cell carcinoma.

Background: Oral squamous cell carcinoma (OSCC) is the most common cancer of the oral cavity. Tumor stage, thickness, lymph node metastasis (LNM), extranodal spread, perineural invasion, tumor differentiation, mutations, human papillomavirus infection and tumor microenvironment are independent prognostic indicators of OSCC. However, clinically, among all factors, LNM is considered an important prognostic factor in OSCC as it not only determines the stage of disease but also the strongest independent factor which predicts recurrence of disease.

Quantitative assessment of tumor-associated tissue eosinophilia and mast cells in tumor proper and lymph nodes of oral squamous cell carcinoma.

Background: Oral squamous cell carcinoma (OSCC) is the most common cancer of oral cavity. Tumor stage, thickness, lymph node metastasis (LNM), extranodal spread, perineural invasion, tumor differentiation, mutations, human papillomavirus infection, and tumor microenvironment are independent prognostic indicators of OSCC. However, clinically, among all factors, LNM is considered an important prognostic factor in OSCC as it not only determines the stage of disease but also the strongest independent factor which predicts recurrence of disease.

Postoperative pathologic assessment of surgical margins in oral cancer: A contemporary review.

Adequacy of resection margins is of utmost importance for decisions regarding postoperative treatment and prediction of prognosis in patients with oral squamous cell carcinoma. However, there are differences in opinions about various basic concepts of surgical margins in oral and maxillofacial pathology. Fundamental issues such as concepts of positive or negative surgical margins and impact of epithelial dysplasia at margin require clarification to standardize the practice of postoperative margin surveillance.

Mandibular step osteotomy using CAD/CAM-derived surgical splint: case report.

Mandibular step osteotomy is a useful technique for large mandibular setbacks. We report a case of a patient who had a mandibular step osteotomy using a CAD/CAM-derived wafer for mandibular setback with reduction of the arch.

Comprehensive and Conservative Management of Talon Cusp: A New Technique.

Talon cusp is a common dental anomaly affecting maxillary central incisors. Gradual grinding of this additional cusp is commonly followed now. Advocated below is a new technique explaining the use of air abrasion and putty index during the stepwise reduction of the cusp.

Endodontic treatment of a mandibular first molar with 8 canals: a case report.

Presented here is a case where 8 canals were located in a mandibular first molar. A patient with continuing pain in mandibular left first molar even after completion of biomechanical preparation was referred by a dentist. Following basic laws of the pulp chamber floor anatomy, 8 canals were located in three steps with 4 canals in each root.

Age changes of jaws and soft tissue profile.

Age-related changes of jaws and soft tissue profile are important both for orthodontists and general dentists. Mouth profile is the area which is manipulated during dental treatment. These changes should be planned in accordance with other components of facial profile to achieve ultimate aim of structural balance, functional efficacy, and esthetic harmony.

The Effect of Time of Post Space Preparation on the Seal and Adaptation of Resilon-Epiphany Se & Gutta-percha-AH Plus Sealer- An Sem Study.

Background: The field of endodontics is dynamic & ever expanding. With the availability of a wide array of products in the dental market it's an absolute necessity to evaluate their efficiency before including them into routine clinical practice.Hence, the purpose of this study is to evaluate the effect of immediate & delayed post space preparation & sealing ability of new root canal filling material & sealers.

Dilemmas pertaining to three canals in the mesiobuccal root of a maxillary second molar: a case report.

The mesiobuccal root of the maxillary molars is well known to pose a hindrance during endodontic therapy. Presented here is a case of a maxillary left second molar where three canals were located in its mesiobuccal root with the use of visual and diagnostic aids. Difficulties encountered during the process of unveiling the tooth's internal anatomy were discussed.

Enlarged lymph nodes in head and neck cancer: Analysis with triplex ultrasonography.

Background: Presence of cervical metastasis is one of the factors influencing the outcome of patients with carcinoma of the head and neck, its early detection is potentially very important. Triplex ultrasonography technology have definitive role in detecting clinically undetectable involvement of lymph nodes (LNs). The purpose of this study was to evaluate, whether triplex ultrasonography characterization of cervical LNs could, with an acceptable degree of certainty, differentiate malignant from benign/reactive LNs, in order to prevent invasive diagnostic procedures.

An in vitro scanning electron microscopic study comparing the efficacy of passive ultrasonic and syringe irrigation methods using sodium hypochlorite in removal of debris from the root canal system.

Objective: To evaluate and compare the cleaning ability of the more biocompatible 1% sodium hypochlorite (NaOCl) with passive ultrasonic irrigation (PUI) to that of 2.5% NaOCl with syringe method irrigation.

Material And Methodology: Thirty-six extracted permanent single-rooted mandibular premolar teeth were decoronated at the cemento-enamel junction and divided randomly into four groups (nine in each group) after biomechanical preparation.

Comparative evaluation of microleakage of silorane-based composite and nanohybrid composite with or without polyethylene fiber inserts in class II restorations: an in vitro study.

Aim: To evaluate microleakage between nanocomposite and silorane composite in class II restorations with or without a polyethylene fiber insert.

Methodology: Standardized class II cavities were prepared on extracted molars and randomly divided into 4 groups (n=20 each): group 1, Ceram X mono; group 2, Ceram X mono + Ribbond; group 3, Filtek P90; and Group 4, Filtek P90 + Ribbond. All specimens were subjected to a thermocycling regime, immersed in 2% methylene blue dye for 24 hours, sectioned longitudinally, and examined under a stereomicroscope to assess dye penetration on a six-point scale.

Interim restorative approach for the management of congenitally missing permanent mandibular incisors: presentation of three cases.

Congenital missing of mandibular permanent incisors with retained primary incisors may jeopardize the esthetic appearance and psychological development of children, especially during the years of transition into adolescence. The retained primary teeth are necessary for the maintenance and normal development of alveolar bone, which in turn is essential for future definitive rehabilitation. In such situations, an interim restoration may be provided before any definitive treatment is given to comfort the young patient during this transition period.