13 results match your criteria: "Oral Punch Biopsy and Scalpel Biopsy"

Application of Targeted Optical Coherence Tomography in Oral Cancer: A Cross-Sectional Preliminary Study.

Diagnostics (Basel)

October 2024

Unit of Oral Medicine and Dentistry for Fragile Patients, Department of Rehabilitation, Fragility, and Continuity of Care, University Hospital "Policlinico Paolo Giaccone" in Palermo, 90127 Palermo, Italy.

Background/objectives: The diagnosis of oral potentially malignant disorders (OPMDs) and oral squamous cell carcinoma (OSCC) represent a significant challenge in oral medicine. Optical coherence tomography (OCT) shows promise for evaluating oral tissue microstructure but lacks standardized diagnostic protocols tailored to the structural variability and lesions of oral mucosa.

Methods: This cross-sectional observational study aims to evaluate the diagnostic accuracy of targeted biopsy-based and site-coded OCT protocols for common OPMDs and OSCC.

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Comparison of tissue artifacts in punch and scalpel biopsies of oral and maxillofacial lesions: A systematic review and meta-analysis.

J Stomatol Oral Maxillofac Surg

December 2020

Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Article Synopsis
  • The study compared tissue artifacts occurring in punch and scalpel biopsies of oral and maxillofacial lesions using systematic review and meta-analysis methodologies.
  • Four studies focusing on various artifacts were included, showing scalpel biopsies were significantly more likely to exhibit issues like crushes, splits, and fragmentation compared to punch biopsies.
  • The findings concluded that punch biopsies generally resulted in fewer artifacts, suggesting they may be the preferable option for obtaining tissue samples in this context.
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Article Synopsis
  • The study investigates the effects of platelet-rich fibrin (PRF) on wound healing following depigmentation surgery, given its known benefits in promoting healing and tissue regeneration.
  • Twelve healthy participants underwent a scalpel depigmentation procedure, with one group receiving PRF treatment and the other using a non-eugenol dressing for comparison.
  • Results showed that the PRF group experienced better pain management, faster healing, and reduced inflammatory response, indicating its effectiveness in improving the wound healing process.
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Background: Oral potentially malignant disorders (OPMDs) and oral cancer (OC) are preventable oral mucosal diseases prevalent in Asian region. This epidemiological study aims to identify oral potentially malignant disorders (OPMDs) and oral cancer (OC), confirm histopathologically, and treat or refer these cases among the population of Eastern Development Region (EDR) of Nepal. It also attempts to assess the risk factors associated in order to compare dose–response measurements of oral habits in these patients.

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Article Synopsis
  • The study aimed to find out which biopsy method is most effective for diagnosing autoimmune blistering diseases (AIBDs) in the oral mucosa.
  • Researchers conducted a retrospective audit on 66 patients who underwent biopsy for suspected AIBD, comparing the effectiveness of incisional versus punch biopsies.
  • Results showed that punch biopsies had a significantly higher diagnostic yield than scalpel biopsies, and the gingiva was identified as the best site for sampling.
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Adjunctive tests cannot replace scalpel biopsy for oral cancer diagnosis.

Evid Based Dent

June 2015

Centre for Evidence-based Dentistry, Dental Health Services Research Unit, University of Dundee, Dundee, Scotland, UK.

Article Synopsis
  • The study analyzed various diagnostic tests (like vital staining and oral cytology) to detect potentially malignant disorders (PMD) or oral cancer using data from multiple medical databases.
  • Independent reviewers assessed the quality of relevant studies and extracted data, focusing on tests used alongside traditional examinations, with scalpel biopsy as the reference standard.
  • The findings indicated that none of the adjunctive tests were reliable enough to replace scalpel biopsy, although oral cytology showed promise due to higher sensitivity and specificity estimates.
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Article Synopsis
  • * This study compares the effectiveness of exfoliative cytology, modified brush biopsy, and traditional biopsy in detecting early oral cancer in patients with precancerous lesions.
  • * Results indicate that modified brush biopsy is more effective than cytology, showing higher specificity and sensitivity, making it a valuable tool for oral cancer screening, while emphasizing the importance of clinical judgment for suspicious cases.
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Sensitivity of direct immunofluorescence in oral diseases. Study of 125 cases.

Med Oral Patol Oral Cir Bucal

May 2008

Facultad de Odontología Universidad de Buenos Aires, Buenos Aires, Argentina.

Article Synopsis
  • Direct immunofluorescence (DIF) is a key method for diagnosing bullous diseases and autoimmune conditions, but its detection rate can be influenced by factors like the biopsy site, the number of biopsies, and the instruments used.
  • A study at the Universidad de Buenos Aires reviewed 136 cases and found that DIF detection rates varied among conditions, with the highest rate in pemphigus vulgaris (100%) and a lower rate in bullous pemphigoid (55.6%).
  • It was discovered that increasing the number of biopsies improved detection rates, and biopsies taken with a punch had a significantly higher detection rate compared to scalpel biopsies (71.7% vs. 39.1%).
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Article Synopsis
  • The authors developed a new tool called "B forceps" for biopsies and compared its effectiveness with traditional methods using specimens from patients diagnosed with oral lichen planus.
  • In a study with 84 patients, group A used conventional biopsy techniques, while group B utilized the B forceps; results showed that group B had significantly fewer issues like fragmentation and hemorrhages.
  • The B forceps not only improved visibility during the procedure but also reduced surgical time and produced higher-quality biopsy specimens with fewer artifacts.
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[Incisional biopsy in oral medicine: punch vs traditional procedure].

Minerva Stomatol

December 2003

Dipartimento di Scienze Stomatologiche G. Messina, Università degli Studi di Palermo, Palermo, Italy.

Article Synopsis
  • The study aimed to compare the punch biopsy technique with the traditional scalpel method in oral medicine for tissue diagnosis.
  • It involved 41 patients divided into two groups, with one receiving punch biopsies and the other receiving traditional scalpel biopsies, with outcomes assessed for pain, healing time, and overall recovery.
  • Results showed no significant differences in these parameters, suggesting that punch biopsy is a reliable and efficient option for oral medical procedures.
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Article Synopsis
  • The study compares artefacts from incisional biopsies using punch versus scalpel techniques, focusing on how suture use affects specimen handling.
  • A total of 160 samples from pig tongues were evaluated by oral surgeons for handling artefacts like crush, splits, fragmentation, and pseudocysts.
  • Findings revealed that while artefacts like crush and fragmentation were similar between methods, stitches increased splits and overall artefacts in scalpel biopsies, suggesting suture usage should be limited to specimen orientation only.
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Effects of an erbium, chromium: yttrium, scandium, gallium, garnet laser on mucocutanous soft tissues.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod

October 1996

Biolase technology inc., San Clemente, Calif., USA.

Article Synopsis
  • The study investigates a new erbium, chromium: yttrium, scandium, gallium, garnet laser system designed for soft tissue surgery and its effectiveness compared to traditional scalpel methods.
  • Using New Zealand white rabbits, researchers analyzed the cutting margins and wound healing of laser versus conventional surgical wounds, discovering minimal blood loss and consistent healing.
  • Results indicate that the new laser system provides effective surgical outcomes, with comparable wound healing to traditional methods, and shows potential for improved diagnostic biopsies.
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Article Synopsis
  • A total of fifty oral biopsy specimens were collected, with 24 taken using a punch method and 26 through traditional incision with a scalpel.
  • The specimens were processed in a histopathology lab to check for artefacts (errors or imperfections in the sample).
  • The results showed that the punch biopsy method had significantly fewer artefacts than the incision method, and access was determined to be satisfactory for the punch technique.
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