75 results match your criteria: "Oral Frictional Hyperkeratosis"
Evaluation of Oral Mucosal Lesions in Iranian Smokers and Non-smokers.
Niger J Clin Pract
April 2024
Oral Medicine Department, Islamic Azad University of Medical Sciences, Tehran, Iran.
Article Synopsis
- The study investigates the link between smoking and oral lesions in the Iranian population, highlighting that the oral mucosa is the first to encounter harmful substances from tobacco.
- Conducted with 200 participants (100 smokers and 100 non-smokers), the research examined various oral conditions and used statistical tests to analyze the data.
- Results indicate that smoking significantly increases the risk of certain oral issues, like coated tongue and smoker's melanosis, while no strong association was found for leukoedema or other lesions.
Smokeless tobacco keratosis in oral mucosa with epithelial dysplasia: A case report.
Medicine (Baltimore)
April 2024
Assistant Professor, Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
Article Synopsis
- Smokeless tobacco use can lead to conditions like smokeless tobacco keratosis (STK), which appears as a white-to-gray plaque in the mouth due to constant irritation from the tobacco products.
- A 50-year-old man with a 24-year history of smokeless tobacco use presented with a painful lesion in his mouth, which was diagnosed as STK with mild dysplastic changes after clinical and histopathological evaluation.
- A management plan emphasizing oral hygiene, cessation of tobacco use, and regular monitoring was implemented, resulting in improvement of the lesion after he stopped using tobacco, highlighting the importance of early detection and education about tobacco's harmful effects.
Frequency of Systemic Diseases and Oral Lesions Among the Institutionalized Elderly Subjects in the Northeast of Iran.
Indian J Dermatol
January 2024
General Dentist, North Khorasan University of Medical Sciences, Bojnord, Iran.
Article Synopsis
- The study focused on the prevalence of systemic diseases and oral lesions among elderly residents in Mashhad Geriatric Institutes.
- Over 224 participants, with an average age of around 76, were examined, revealing common systemic issues like hypertension, Alzheimer's, and diabetes, with a significant portion having multiple concurrent diseases.
- Notably, 97.1% of the participants had at least one oral lesion, with fissured tongue and sublingual varicosities being the most prevalent, highlighting the need for regular oral examinations in the elderly for early detection and treatment.
Prevalence of Keratosis in the Oral Cavity: A Clinical Retrospective Study.
Cureus
January 2024
Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Article Synopsis
- The paper examines the occurrence of three benign white lesions in the oral cavity—frictional keratosis, tobacco pouch keratosis, and morsicatio buccarum—among patients at Saveetha Dental College, focusing on gender and age distribution.
- A retrospective analysis of data from over four years revealed 5,613 patients with these lesions, with frictional keratosis being the most prevalent, particularly among middle-aged men.
- The study utilized the Statistical Package for the Social Sciences (SPSS) for analysis, highlighting the need for simple treatment in most cases, as these lesions are generally harmless.
"Shot on Target": A Case of an Unusual Peripheral Ossifying Fibroma of the Edentulous Upper Jaw Irritated by the Only Teeth of the Lower Jaw.
Cureus
October 2023
Dentoalveolar Surgery, Implantology and Oral Radiology, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.
A peripheral ossifying fibroma (POF) is a benign, localized lesion that originates from the periosteum or periodontal ligament after traumatic or calculus irritation. The lesions typically manifest in females throughout their second and third decades of life. The diagnosis of a POF is challenging from both clinical and histological standpoints, as it exhibits overlapping features with numerous other clinical entities.
View Article and Find Full Text PDFPachyonychia Congenita: Clinical Features and Future Treatments.
Keio J Med
September 2023
Centre for Cell Biology and Cutaneous Research, Blizard Institute, The Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Pachyonychia congenita (PC) is a rare, autosomal dominant inherited disorder of keratinization that is characterized by a triad of focal palmoplantar keratoderma, plantar pain, and hypertrophic nail dystrophy. It can be debilitating, causing significantly impaired mobility. PC is diagnosed clinically alongside identification of a heterozygous pathogenic mutation in one of five keratin genes: KRT6A, KRT6B, KRT6C, KRT16, or KRT17.
View Article and Find Full Text PDFThe importance of early treatment of oral squamous cell carcinoma: Case report.
Oral Oncol
September 2023
Oral Semiology and Oral Pathology, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.
Article Synopsis
- Oral squamous cell carcinoma (OSCC) often presents at an advanced stage, leading to a low five-year survival rate, but early detection and treatment can significantly improve outcomes.
- The case study of a 74-year-old man with a persistent tongue lesion highlights the importance of timely surgical excision, which can prevent complications and enhance patient outcomes.
- Recognizing and addressing intraoral lesions promptly is crucial to avoid more invasive procedures associated with advanced OSCC.
ORAL CHANGES IN PEDIATRIC PATIENTS WITH EATING DISORDERS.
Acta Clin Croat
August 2022
Department of Removable Prosthodontics, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Article Synopsis
- * Common oral problems identified include dental plaque, gingivitis, and various forms of cheilitis, with specific correlations found between certain issues and disease duration or age.
- * Findings suggest a connection among oral manifestations and nutritional disorder severity, indicating that more targeted research could help clarify these relationships further.
Wolf in sheep's clothing - Oral proliferative verrucous leukoplakia: Progression with longitudinal molecular insights.
Ann Diagn Pathol
April 2023
Anatomic Pathology, Division of Laboratory Medicine, Head and Neck Disease Alignment Team, City of Hope Cancer Center, 1500 Duarte Rd., CA 91010, United States of America. Electronic address:
Article Synopsis
- Oral proliferative verrucous leukoplakia (OPVL) is a chronic mouth condition that can progress to a more severe form of disease and is often mistaken for other oral lesions.
- The study analyzed changes in molecular signatures during OPVL progression by examining samples from patients and comparing them to those with oral squamous cell carcinoma (OSCC).
- Significant genetic mutations were found in OPVL patients, particularly in the TERT promoter and TP53 gene, suggesting that OPVL has similarities to OSCC that could help inform treatment and diagnostic approaches.
Oral lesions and periodontal status in diabetics and non-diabetics: A hospital based study.
J Oral Maxillofac Pathol
October 2022
Department of Oral Pathology, Dental College, RIMS, Imphal, Manipur, India.
Article Synopsis
- The study focuses on the oral health of individuals with type 1 and type 2 diabetes, highlighting that diabetes can lead to specific oral problems such as xerostomia (dry mouth) and chronic periodontitis.
- Conducted at a diabetes care center in Chennai, the research involved comparing 110 diabetic patients with 100 healthy non-diabetic individuals to assess oral health using specific dental indices.
- Results showed a significant link between diabetes and both xerostomia and periodontal disease, but did not support previous findings regarding other oral issues like traumatic ulcers and lichen planus.
Darier Disease Presenting with Recurrent Kaposi Varicelliform Eruption in a 10-year-old Boy with Seborrheic Dermatitis.
Acta Dermatovenerol Croat
November 2021
Marta Navratil, MD, PhD, Department of Pulmonology, Allergology, Rheumatology and Clinical Immunology, Children's Hospital Zagreb, Klaićeva 16, 10000 Zagreb, Croatia;
Article Synopsis
- A 10-year-old boy with seborrheic dermatitis (SD) was referred for recurring Kaposi varicelliform eruption (KVE) linked to herpes simplex virus (HSV-1) and possible primary immunodeficiency.
- He has a history of skin issues since infancy, and his family has no known history of skin disorders or immunodeficiency, although he does have a sensory processing disorder.
- Medical evaluations revealed normal immunoglobulin levels but a lower T-cell count, leading to a diagnosis of Darier disease (DD) after unsuccessful treatments for his skin flare-ups.
Unusual Clinical Presentation of Giant Extragenital Condyloma.
Acta Dermatovenerol Croat
December 2020
Andrija Jovic, MD, Clinical Center of Nis, Clinic of Dermatovenereology, Bulevar Zorana Djindjica 48, Nis, Serbia;
Article Synopsis
- Condylomata acuminatum (CA) is a type of STI caused by HPV, usually found in the genital area, but this case reports a rare occurrence of giant linear CA on extragenital skin.
- A 70-year-old man presented with a large, asymptomatic lesion on his abdomen, initially mistaken for seborrheic keratosis, and was diagnosed through a combination of dermatoscopy and biopsy.
- The biopsy confirmed CA associated with HPV type 6, and the lesions were successfully treated with electrosurgery; regular follow-up is planned.
Lichenoid morphology could be an early feature of oral proliferative verrucous leukoplakia.
J Oral Pathol Med
February 2021
Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, WHO Collaborating Centre for Oral Cancer, London, UK.
Article Synopsis
- Recognition of early proliferative verrucous leukoplakia (PVL) can often be confused with other conditions like frictional keratosis and lichen planus, making accurate diagnosis challenging for clinicians.
- A study of 51 patients revealed that many had initial diagnoses that didn't indicate PVL; about 43% showed lichen planus features in their biopsies.
- Notably, 21.5% of the patients experienced malignant transformation during follow-up, indicating the importance of monitoring these cases closely for potential progression.
The use of Velscope to assess cellular changes occuring in oral premalignancy.
J Oral Biol Craniofac Res
March 2020
Dept. of Oral and Maxillofacial Surgery, Dr. D.Y. Patil Vidyapeeth, Pune, India.
Article Synopsis
- - The study aimed to enhance the visualization of suspicious oral mucosa lesions and evaluate the Velscope's effectiveness in detecting cellular changes related to oral premalignancy for early diagnosis.
- - Involving 250 patients with a history of chewing tobacco, 200 were screened, and only 110 underwent biopsy; 89 showed neoplastic changes, while control biopsies were all benign.
- - Although the Velscope can improve clinical decision-making and help identify biopsy sites, its high false positive rate and poor specificity limit its use as a reliable screening tool.
Benign Alveolar Ridge Keratosis: Clinical and Histopathologic Analysis of 167 Cases.
Head Neck Pathol
December 2020
Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, MA, 02215, USA.
Article Synopsis
- Benign alveolar ridge keratosis (BARK) is a non-cancerous condition resembling chronic skin irritation, primarily caused by trauma or friction, appearing as a white patch in the mouth, especially near the retromolar pad and alveolar ridge.
- A study identified 167 cases of BARK from 2016 to 2017, mostly affecting males with a median age of 56 years, and found that about 64% of cases occurred in the retromolar area.
- Histological analysis showed characteristic features like thickened skin layers and subtle cell changes, while a p53 study indicated minimal abnormal protein expression, distinguishing BARK from more serious conditions like leukoplakia.
Loricrin expression and its implication in oral submucous fibrosis, hyperkeratosis and normal mucosa with association to habits - An immunohistochemical study.
J Oral Biol Craniofac Res
May 2019
Department of Oral Pathology and Microbiology, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India.
Article Synopsis
- The study investigates how areca nut chewing and mechanical stress affect the oral mucosa, particularly focusing on the protein Loricrin, which is linked to changes in keratinocytes and may indicate early signs of oral conditions.
- A total of 73 tissue samples were analyzed, classified into normal mucosa, hyperkeratotic, and oral submucous fibrosis, and stained for Loricrin to assess its expression levels.
- Results showed a significant correlation between Loricrin expression and chewing habits, suggesting it might serve as an early diagnostic marker for conditions like oral submucous fibrosis.
Oral Epithelial Dysplasia and Premalignancy.
Head Neck Pathol
September 2019
Harvard School of Dental Medicine, Boston, MA, USA.
Article Synopsis
- - Leukoplakia and erythroplakia are oral conditions linked to oral epithelial dysplasia (OED) and can signify a potential for cancer, while lesions like submucous fibrosis only show OED after several years.
- - Traumatic keratoses can be confused with leukoplakia, making it crucial for pathologists to properly identify these conditions.
- - Early stages of proliferative leukoplakia often show only hyperkeratosis, with more severe issues like OED or squamous cell carcinoma developing later, and a specific lymphocyte presence can be misinterpreted as oral lichen planus.
Frictional Keratosis, Contact Keratosis and Smokeless Tobacco Keratosis: Features of Reactive White Lesions of the Oral Mucosa.
Head Neck Pathol
March 2019
Atlanta Oral Pathology, Emory Decatur Hospital, Emory University School of Medicine, 2701 N. Decatur Road, Decatur, GA, 30033, USA.
Article Synopsis
- White lesions in the oral cavity are common and can range from benign to malignant, with many articles primarily addressing leukoplakia and other potentially dangerous types.
- This review specifically examines reactive white oral lesions, such as frictional keratoses, irritant contact stomatitis, and smokeless tobacco keratoses.
- The text also discusses differential diagnoses like leukoedema and hereditary conditions, emphasizing that various products, including certain toothpastes and materials, can cause these keratotic lesions, which have unique microscopic characteristics that aid in patient care.
Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.
J Periodontol
June 2018
Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Japan.
Article Synopsis
- - Periodontal health is characterized by no detectable inflammation, and can exist in both healthy and treated periodontitis patients, with a clear distinction between intact and reduced periodontium.
- - There are two main types of gingival diseases: non-dental plaque biofilm-induced diseases, which don't resolve with plaque removal, and dental plaque-induced gingivitis, which can be influenced by both local and systemic factors.
- - Even treated periodontitis patients can experience a heightened risk of recurrent disease, making it essential for ongoing monitoring and risk assessment to prevent further complications.
Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.
J Clin Periodontol
June 2018
Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Japan.
Article Synopsis
- - Periodontal health is characterized by the absence of visible inflammation and can occur in healthy gums as well as in patients who have had past gum disease but are now stable; however, those with a history of periodontitis are at risk for recurrence and need ongoing monitoring.
- - Gingival diseases are categorized into two main types: non-dental plaque biofilm-induced diseases, which are not caused by plaque and usually don't improve with plaque removal, and dental plaque-induced gingivitis, which is influenced by both local and systemic factors.
- - Effective management of gingival health involves identifying and addressing both types of gingival diseases and requires regular assessments, particularly for individuals with a history of periodontal disease to prevent potential relapse.
Prevalence and Distribution of Oral Mucosal Lesions by Sex and Age Categories: A Retrospective Study of Patients Attending Lebanese School of Dentistry.
Int J Dent
May 2018
Faculty of Pharmacy, Lebanese University, Beirut, Lebanon.
Background: Prevalence and distribution of oral mucosal lesions in a sample of Lebanese population attending the School of Dentistry of Lebanese University is necessary to evaluate their oral health situation.
Objectives: The aim of the present study was to determine the prevalence and distribution of oral mucosal lesions of patients attending the School of Dentistry.
Methods: A descriptive study was carried out by retrospectively examining a total of 231 medical and clinical examination record files of patients, attending the School of Dentistry Lebanese University for multidisciplinary dental treatments.
Oral epithelial dysplasia, atypical verrucous lesions and oral potentially malignant disorders: focus on histopathology.
Oral Surg Oral Med Oral Pathol Oral Radiol
June 2018
Emory University School of Medicine, Atlanta Oral Pathology, Decatur, GA, USA. Electronic address:
Article Synopsis
- Oral potentially malignant disorders (OPMDs) are mucosal diseases that have the potential to develop into squamous cell carcinoma, with oral leukoplakia being the most common type, having a low prevalence but notable malignant transformation rates.
- The evaluation of OPMDs involves subjective histopathologic assessments which can lead to variability in diagnosis, particularly concerning oral epithelial dysplasia and atypical verrucous lesions.
- This review emphasizes the need for better understanding of the histologic characteristics of OED and atypical verrucous keratoses, as well as the challenges posed by conditions that mimic OPMDs, which can lead to mismanagement of patients.
Oral lesions as an important marker for HIV progression.
Dermatol Online J
September 2017
Laboratory of Virology, Institute of Tropical Medicine of São Paulo, University of São Paulo, São Paulo, Brazil 2 Department of Stomatology, Division of General Pathology, School of Dentistry, University of São Paulo, São Paulo, Brazil. br.
Article Synopsis
- - Oral hairy leukoplakia (OHL) is a benign condition linked to EBV, primarily seen in immunosuppressed individuals like HIV+ adults, and is rare in kids.
- - This study presents two HIV+ adolescents with tongue lesions; only one was confirmed to have OHL using specific testing methods.
- - Confirming OHL can significantly aid in the medical management of HIV+ pediatric patients, allowing for appropriate treatment planning.
Time-resolved fluorescence spectroscopy for the diagnosis of oral lichen planus.
Clin Exp Dermatol
July 2018
Department of Dermatology, Davis Medical Center, University of California-Davis, Sacramento, CA, USA.
Article Synopsis
- Lichen planus (LP) is an autoimmune disorder affecting skin and mucous membranes, typically diagnosed through clinical evaluation and oral biopsy.
- The study aimed to use time-resolved fluorescence spectroscopy (TRFS) to identify differences in fluorescence lifetime between diseased and normal oral tissues.
- Preliminary results indicated that TRFS can significantly differentiate between normal and lesional tissue noninvasively, suggesting its potential as an innovative diagnostic tool for oral lichen planus.