2,421 results match your criteria: "Oral Fibromas and Fibromatoses"

Oral Verruciform Xanthoma of the Lower Lip: A Rare Entity.

Cureus

November 2024

Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.

Oral verruciform xanthoma (OVX) is a rare entity, and only a handful of cases have been reported in the literature to date. This innocent-looking lesion can mimic any benign epithelial or connective tissue origin neoplasm. It can present with variations in surface color and texture.

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Ossifying fibroma and juvenile ossifying fibroma: A systematic review on clinical and radiological parameters, treatment modalities and recurrence.

J Stomatol Oral Maxillofac Surg

December 2024

Nantes Université, CHU Nantes, Service de Chirurgie Maxillo-Faciale et Stomatologie, F-44000, Nantes, France; Nantes Université, Univ Angers, CHU Nantes, INSERM, CNRS, CRCI2NA, F-44000, Nantes, France. Electronic address:

Ossifying fibroma (OF) is a rare benign fibro-osseous neoplasm developing mostly in maxillo-facial bones. OF is divided in cemento-ossifying fibroma (COF), juvenile trabecular ossifying fibroma (JTOF) and psammomatoid ossifying fibroma (PSOF). The aim of this systematic review was to synthetize the existing literature on OF, investigating the clinical and radiological parameters related to the different forms of the disease, and to compare the treatment modalities according to their associated recurrence rate.

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Primary bone tumours of the jaw are rare tumoral entities and do substantially differ from other bone tumours of the human body with respect of their frequently encountered unusual radiological appearances. The reason for that may be confined to the co-existence of two closely neighbored but different anatomical structures (i.e.

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Primary bone tumours of the jaw are rare tumoral entities and do substantially differ from other bone tumours of the human body with respect of their frequently encountered unusual radiological appearances. The reason for that may be confined to the co-existence of two closely neighbored but different anatomical structures (i.e.

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Oral fibromas typically appear as smooth bumps that match the color of the surrounding oral tissues and usually do not cause additional symptoms. They are benign tumors of fibrous tissue origin that develops as a result of continuous irritation or damage. Fibroma is the most common benign soft tissue tumor in the mouth.

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Article Synopsis
  • The study investigates oral health issues and their links to systemic diseases among geriatric patients aged 60 and older, conducted at Krishna Vishwa Vidyapeeth's Department of Oral Medicine and Radiology over six months from January to June 2024.
  • A total of 100 geriatric patients were examined, with data collected on demographics, personal habits, and medical history, revealing that hypertension and tobacco use were significant findings among the group.
  • Common oral health problems identified included periodontitis, partial edentulism, dental caries, and soft tissue issues such as gingivitis and oral cancer, emphasizing the need for targeted dental care for elderly patients.
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The Diagnostic Considerations and Clinical Management of Lower Lip Swellings in Adolescents: A Narrative Review.

Cureus

October 2024

Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.

This article outlines a systematic workflow for the clinical management of lip swellings, ensuring an accurate diagnosis and appropriate treatment plan. The process involves a thorough clinical examination and necessary diagnostic investigations such as imaging and biopsy, which will guide treatment decisions. Depending on the findings, treatment may range from conservative management to surgical excision.

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Background: To examine the prevalence and pattern of pathology related to impacted teeth and other areas in the Department of Oral and Maxillofacial Surgery of the Government Dental College in Chhatrapati Sambhajinagar.

Material And Methods: This 5-year single-center retrospective cohort study was conducted in the department of oral and maxillofacial surgery at the government dental college and hospital in Chhatrapati Sambhajinagar between 2019 and 2024. Based on age, sex, area, presence of impacted tooth, radiological and histopathological report.

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Trabecular Juvenile Ossifying Fibroma Involving the Maxilla: A Rare Case.

Cureus

October 2024

Oral and Maxillofacial Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.

Trabecular juvenile ossifying fibroma (TrJOF) is a rare, benign, fibro-osseous lesion that predominantly affects children and adolescents. The lesion is locally aggressive, has a high recurrence rate, and is often misdiagnosed due to its clinical and radiographic similarities to other lesions. A seven-year-old female presented with a history of swelling and pain on the right side of her face for the last month.

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A generalizable procedure for Brown's class Ⅱ and Ⅲ defects reconstruction with deep circumflex iliac artery flap using computer-assisted technique.

J Craniomaxillofac Surg

November 2024

Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, 430079, Wuhan, China; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, 430079, Wuhan, China. Electronic address:

Objective: This study summarizes and analyzes the characteristics of deep circumflex iliac artery (DCIA) flap reconstruction for maxillary defects and proposes a generalized protocol under the guidance of computer-assisted technique to enhance surgical efficiency and success rate.

Materials And Methods: We retrospectively reviewed 10 cases of maxillary defects reconstructed using DCIA flaps under the application of computer-assisted technique, collecting clinical data for statistical analysis.

Results: These cases included 2 cystic lesions, 2 mucinous tumors, 2 ameloblastomas, 1 mucoepidermoid carcinoma, 1 odontogenic fibroma, 1 bone defect following squamous cell carcinoma (SCC) surgery, and 1 ossifying fibroma.

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The Management of Peripheral Ossifying Fibroma: A Case Presentation.

Cureus

October 2024

Department of Oral Pathology and Microbiology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

One of the most frequent conditions found in the oral cavity includes reactive lesions. Peripheral ossifying fibroma (POF) is a prevalent condition characterized by an overgrowth, originating from the gingival tissue, periodontal ligament, and periosteum. The condition manifests as a small mucosal nodule and can be difficult to accurately identify since it resembles other lesions.

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Ameloblastic fibroma (AF) and related lesions, namely ameloblastic fibrodentinoma (AFD) and ameloblastic fibro-odontoma (AFO), span a spectrum from true neoplasms to hamartomas. The 2017 World Health Organization classification proposes that AFD and AFO are precursors to odontomas, yet their precise nature remains uncertain. This study examined 19 AF cases, 4 AFD, 15 AFO, 19 odontomas (OD, 14 complex, 5 compound), and 2 ameloblastic fibrosarcomas (AFS), focusing on clinical characteristics, recurrence, and molecular profiles.

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Objective: Determine the prevalence, types, and geographical distribution of oral tumors in dogs in Switzerland to provide insights into demographics, tumor characteristics, and trends.

Methods: The medical and pathology records of dogs diagnosed with oral tumors from 2012 to 2022 were sourced from diagnostic laboratories in Switzerland. The focus was on histopathologically confirmed oral neoplasms.

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The acetylation of histones H2A on lysine 5 (H2AacK5) and H3 on lysine 27 (H3AcK27) modulate several cellular mechanisms through the p300 enzyme in pathological lesions; however, their role in odontogenic lesions has not been addressed. This study aims to evaluate the immunoexpression of p300, H2AacK5, and H3AcK27 in samples of ameloblastoma (AMB) (n = 30), odontogenic keratocyst (OK) (n = 15), adenomatoid odontogenic tumor (AOT) (n = 10), odontogenic fibroma (OF) (n = 8), calcifying odontogenic cyst (COC) (n = 8), odontogenic myxoma (MIX) (n = 10), and ameloblastic fibroma (AF) (n = 06). The percentage of p300-positive cells was higher in AOT and decreased in COC, OK, AMB, AF, OF, and MIX.

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Objective: Our study aims to assess alendronate-related adverse events (AEs) from the US FDA adverse event reporting system database.

Methods: The AE data associated with alendronate between the first quarter of 2004 and the first quarter of 2024 were selected. Various signal quantification methods, including the ROR, PRR, BCPNN, and EBGM, were applied for analysis.

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Successful Management of an Emerging Distinct Gingival Lesion With a New Histopathological Identity.

Cureus

October 2024

Oral and Maxillofacial Surgery, College of Dentistry, Qassim University, Buraydah, SAU.

Gingival fibroma is a pathological condition that can manifest in pediatric and adult patients, often presenting diagnostic challenges due to shared histopathological characteristics among various lesions. It has been reported as a novel category with distinct histopathological features with new diagnostic criteria. A 40-year-old Saudi female patient with no significant medical history reported a 4×3 cm pedunculated, non-tender, firm, red gingival growth adjacent to the remaining root of tooth number 27 in the maxillary left side.

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Article Synopsis
  • The study aims to compile and summarize information about desmoplastic fibroma in the jaw bones, focusing on its key characteristics.
  • A systematic review identified 66 articles detailing 96 cases, revealing a higher prevalence in females and younger patients, particularly affecting the mandible, with painless swelling as the primary symptom.
  • Surgical removal is the standard treatment with a recurrence rate of 10.8%, and histopathological analysis shows specific cellular and molecular features that require more research for understanding the tumor's development.
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Exploring mutations: GNAS and CDC73 in jaw fibroosseous lesions.

Pathol Res Pract

November 2024

Department of Oral pathology and Microbiology, Centre for dental education and research, All India Institute of Medical Sciences, New Delhi, India. Electronic address:

Article Synopsis
  • Benign fibro-osseous lesions, including ossifying fibroma (OF) and fibrous dysplasia (FD), are challenging to differentiate due to similarities in their features, making accurate diagnosis important for treatment.
  • This study aimed to evaluate mutations in the GNAS and CDC73 genes in blood and formalin-fixed tumor tissues from OF and FD cases, involving six blood samples and thirteen tumor samples.
  • Findings revealed a pathogenic GNAS mutation linked to McCune-Albright syndrome in FD blood samples, but extraction from tumor tissues was unsuccessful, suggesting possible issues with the fixation process affecting DNA quality.
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Background: Calcifying odontogenic cysts (Gorlin cysts) most commonly present centrally and have only rarely been reported in peripheral locations. The purpose of this report is to describe a new case of peripheral calcifying odontogenic cyst (PCOC) occurring in the anterior maxillary gingiva and to review the management and differential diagnosis of such a lesion.

Methods: A 37-year-old female presented with a long-standing submucosal nodule on the gingiva between the maxillary central incisors, with asymptomatic growth over the last three years.

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Article Synopsis
  • Intraosseous myofibroma is a rare jaw tumor primarily affecting young boys, often not well understood in the medical community.
  • A case study of a 2-year-old boy showed a painless swelling that was initially misdiagnosed, and further analysis revealed it was an intraosseous myofibroma after surgical removal.
  • This case highlights the importance of thorough histopathological examination in diagnosing rare tumors in children and ensuring successful treatment outcomes.
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