1 results match your criteria: "Ophthalmology and ENTComplutense University School of MedicineMadridSpain.[Affiliation]"
An Experimental DUAL Model of Advanced Liver Damage.
Hepatol Commun
June 2021
Department of Immunology, Ophthalmology and ENTComplutense University School of MedicineMadridSpain.
Article Synopsis
- The study investigates the effects of combining intermediate alcohol consumption with a Western diet to create a mouse model (DUAL) that simulates both alcohol-associated and metabolic fatty liver diseases.
- Mice on the DUAL diet showed significant weight gain, liver damage, and signs of metabolic distress, including increased fat cell size, high cholesterol, and high blood sugar levels.
- The findings suggest that this DUAL model closely resembles human advanced steatohepatitis, making it a useful preclinical tool for finding new treatments.