4 results match your criteria: "Ophthalmology Department and Laboratory of Eye Research Felsenstein Medical Research Center[Affiliation]"
[ASPECTS AFFECTING PEDIATRIC OPHTHALMOLOGY AND STRABISMUS PUBLICATION TIMES].
Harefuah
December 2023
Arrow Program for Medical Research Education, Sheba Medical Center, Tel Hashomer, Israel, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Goldschlager Eye Institute, Sheba Medical Center, Tel Hashomer, Israel.
Background: To better understand and analyze various aspects of scientific publication, bibliometric data analysis is useful.
Objectives: An analysis of the factors associated with shorter publication times in pediatric ophthalmology and strabismus (POS) between the years 2002 and 2007, compared to 2014 and 2018.
Methods: In this retrospective bibliometric analysis, we analyzed 2,487 articles related to POS from the official websites of 8 preselected ophthalmology journals.
3K3A-Activated Protein C Inhibits Choroidal Neovascularization Growth and Leakage and Reduces NLRP3 Inflammasome, IL-1β, and Inflammatory Cell Accumulation in the Retina.
Int J Mol Sci
June 2023
Rabin Medical Center, Ophthalmology Department and Laboratory of Eye Research Felsenstein Medical Research Center, Petah-Tikva 5251108, Israel.
Article Synopsis
- 3K3A-Activated Protein C (APC) is a new anticoagulant that offers protective benefits and a lower risk of bleeding, showing promise for treating choroidal neovascularization (CNV), which can lead to vision loss.
- In experiments using a mouse model with laser-induced CNV, 3K3A-APC was injected into the eye, revealing its effects on immune cell activation and inflammatory markers.
- The results showed that 3K3A-APC reduced harmful immune responses and inflammation, leading to a decrease in CNV growth and leakage, suggesting it could be a effective multi-target treatment for this eye condition.
Long-Term Evaluation of Pseudoexfoliation Syndrome Post-Cataract Extraction.
J Pers Med
May 2023
Ophthalmology Department and Laboratory of Eye Research Felsenstein Medical Research Center, Rabin Medical Center, Petach Tikva 4941492, Israel.
The study aimed to examine the effect of cataract extraction on ophthalmologists' ability to detect pseudoexfoliation (PXF) syndrome. A total of 31 patients admitted for elective cataract surgery were enrolled in this prospective comparative study. Prior to surgery, patients underwent slit-lamp examination and gonioscopy conducted by experienced glaucoma specialists.
View Article and Find Full Text PDFActivated Protein C (APC) and 3K3A-APC-Induced Regression of Choroidal Neovascularization (CNV) Is Accompanied by Vascular Endothelial Growth Factor (VEGF) Reduction.
Biomolecules
February 2021
Rabin Medical Center, Ophthalmology Department and Laboratory of Eye Research Felsenstein Medical Research Center, Petah-Tikva 49100, Israel.
The activated protein C (APC) ability to inhibit choroidal neovascularization (CNV) growth and leakage was recently shown in a murine model. A modified APC, 3K3A-APC, was designed to reduce anticoagulant activity while maintaining full cytoprotective properties, thus diminishing bleeding risk. We aimed to study the ability of 3K3A-APC to induce regression of CNV and evaluate vascular endothelial growth factor (VEGF) role in APC's activities in the retina.
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