2 results match your criteria: "Ophthalmological Institute of Shaanxi Province[Affiliation]"
Establishment of a novel therapeutic vector targeting the trigeminal ganglion in rats.
Drug Des Devel Ther
October 2016
Department of Ophthalmology, The No 1 Hospital of Xi'an, Xi'an, Shaanxi Province, People's Republic of China; Shaanxi Provincial Key Laboratory of Ophthalmology, Ophthalmological Institute of Shaanxi Province, Xi'an, Shaanxi Province, People's Republic of China.
Background: In the pathogenesis of herpes simplex keratitis, herpes simplex virus type 1 (HSV-1) infection begins in corneal epithelium cells and then progresses through the sensory nerve endings and finally travels up forward to the trigeminal ganglion (TG), where it remains as latent virus. The available anti-HSV therapies do not completely suppress the recurrence of active HSV-1 infection. The aim of this study was to establish a novel replication-defective (rd) HSV-1 (rdHSV) vector (rdHSV-interferon gamma [IFNγ]) that could effectively target the TG.
View Article and Find Full Text PDFCorneal ulcer caused by nocardia brasiliensis in a patient with diabetes.
Int J Ophthalmol
May 2014
Biomanufacturing Engineering Laboratory, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, Guangdong Province, China.