7 results match your criteria: "Onze-Lieve-Vrouwziekenhuis Clinic[Affiliation]"

Why Do Coronaries Spasm?: Getting to Grips With Atherosclerosis as a Substrate.

JACC Cardiovasc Imaging

August 2024

Cardiovascular Center Aalst, Onze Lieve Vrouwziekenhuis Clinic, Aalst, Belgium; Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland. Electronic address:

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Article Synopsis
  • A study was conducted to improve the prediction of which coronary artery lesions could lead to acute coronary syndrome (ACS) by integrating artificial intelligence (AI) with traditional methods.
  • The research focused on patients who had undergone coronary CT angiography (CTA) before experiencing an ACS event, analyzing both culprit (problematic) and nonculprit lesions.
  • The new model incorporating AI features showed significantly better predictability for identifying high-risk lesions compared to standard methods, suggesting that AI can enhance cardiac risk assessment.
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Importance: Guidelines recommend deferral of testing for symptomatic people with suspected coronary artery disease (CAD) and low pretest probability. To our knowledge, no randomized trial has prospectively evaluated such a strategy.

Objective: To assess process of care and health outcomes in people identified as minimal risk for CAD when testing is deferred.

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Article Synopsis
  • A recent clinical trial tested a new coronary computed tomography angiography (cCTA) strategy, aimed at improving efficiency for patients with stable chest pain compared to traditional stress testing methods.
  • The trial, involving over 2000 participants from North America and Europe, assigned patients to either a precision strategy (PS) using risk assessment for testing decisions or usual testing (UT), which included stress tests.
  • Results showed that the PS group had significantly lower rates of unnecessary catheterizations and better efficiency outcomes than the UT group, indicating that the new approach could enhance patient care.
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Objectives: The aim of this study was to develop a new model for assessment of stenosis severity in a bifurcation lesion including its core. The diagnostic performance of this model, powered by 3-dimensional quantitative coronary angiography to predict the functional significance of obstructive bifurcation stenoses, was evaluated using fractional flow reserve (FFR) as the reference standard.

Background: Development of advanced quantitative models might help to establish a relationship between bifurcation anatomy and FFR.

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The prognostic relevance of direct contrast toxicity in patients treated with primary percutaneous coronary intervention remains unclear, owing to the confounding hemodynamic effect of acute left ventricular ejection fraction (LVEF) impairment on kidney function estimation. In the present study, 644 consecutive patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention were prospectively enrolled. Contrast-induced nephropathy (CIN) was defined as an increase in serum creatinine >25% or a decrease in the estimated glomerular filtration rate (eGFR) <25% from baseline in the first 72 hours.

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We report the case of 67-year-old woman who underwent aortic valve replacement and mitral valve repair due to ochronotic valvular disease (alkaptonuria), which was diagnosed incidentally during cardiac surgery.

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