2 results match your criteria: "Ontario. lmcintyre@ottawahospital.on.ca[Affiliation]"
Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury.
Neurocrit Care
October 2006
Centre for Transfusion and Critical Care Research, Clinical Epidemiology Unit, Critical Care Program, University of Ottawa and Ottawa Health Research Institute, Ottawa, Ontario.
Objective: To compare a restrictive versus a liberal transfusion strategy in patients with moderate to severe closed head injury following multiple trauma in 13 Canadian intensive care units (ICUs).
Methods: This is a subgroup analysis of a multicenter randomized controlled clinical trial involving sixty-seven critically ill patients from the Transfusion Requirements in the Critical Care trial who sustained a closed head injury. Patients had a hemoglobin concentration less than 9.
Is a restrictive transfusion strategy safe for resuscitated and critically ill trauma patients?
J Trauma
September 2004
Centre for Transfusion and Clinical Epidemiology Program, Ottawa Health Research Institute, Ontario.
Background: An analysis from the prospective multicenter randomized controlled trial (Transfusion Requirements in Critical Care Trial) compared the use of restrictive and liberal transfusion strategies with resuscitated critically ill trauma patients.
Methods: Critically ill trauma patients with a hemoglobin concentration less than 90 g/L within 72 hours of admission to the intensive care unit were randomized to a restrictive (hemoglobin concentration, 70 g/L) or liberal (hemoglobin concentration, 100 g/L) red blood cell transfusion strategy.
Results: The baseline characteristics in the restrictive (n = 100) and liberal (n = 103) transfusion groups were comparable.