Neural response to errors among mothers with a history of recurrent depression and their adolescent daughters.

Depression is transmitted within families, but the mechanisms involved in such transmission are not clearly defined. A potential marker of familial risk is the neural response to errors, which may play a role in depression symptoms and is known to be partially heritable. Here, 97 mother-daughter dyads completed a Flanker task while electroencephalography markers of error monitoring were recorded: the error-related negativity (ERN) and response-locked delta and theta power.

Exploring caregiver experiences and support needs in end-of-life care for people living with HIV: A scoping review protocol.

Background And Objectives: End-of-life care supports individuals in the last few weeks or months of their life and their caregivers, offering psychosocial support, symptom management and relief, and resources. While some of the first public end-of-life care facilities were established due to HIV/AIDS, the current needs of caregivers for people living with end-stage HIV are not well understood. Caregivers provide two-thirds of the care for people living with HIV, yet their specific support needs and experiences are under-researched.

Unilateral and bilateral theta burst stimulation for treatment-resistant depression: Follow up on a naturalistic observation study.

Objectives: Theta burst stimulation (TBS) is a novel and faster modality of transcranial magnetic stimulation, which is showing promise as a treatment-resistant depression (TRD) treatment. Though TBS can be applied unilaterally or bilaterally, few studies have compared the effectiveness of both approaches in a naturalistic clinical sample. In this retrospective chart review, we aimed to: (1) replicate previous bilateral sequential TBS effectiveness in a larger cohort of patients at a single centre, (2) present treatment outcome data between unilateral and bilateral TBS approaches, (3) investigate baseline factors associated with our observed outcomes, and (4) examine the sustainability of response, with follow-up data up to 6 months from patients.

Assistive Technology to Support Dementia Management: Protocol for a Scoping Review of Reviews.

Background: In Canada, more than 60% of persons living with dementia reside in their own homes, and over 25% rely heavily on their care partners (ie, family members or friends) for assistance with daily activities such as personal hygiene, eating, and walking. Assistive technology (AT) is a key dementia management strategy, helping to maintain health and social support in home and community settings. AT comprises assistive products and services required for safe and effective use.

Stratified Care in Cognitive Behavioural Therapy: A Comparative Evaluation of Predictive Modelling Approaches for Individualized Treatment: La stratification des soins pour l'orientation vers une thérapie cognitivo-comportementale: une évaluation comparative des approches de modélisation prédictive pour un traitement individualisé.

Objective: In response to high demand and prolonged wait times for cognitive behavioural therapy (CBT) in Ontario, Canada, we developed predictive models to stratify patients into high- or low-intensity treatment, aiming to optimize limited healthcare resources.

Method: Using client records ( = 953) from Ontario Shores Centre for Mental Health Sciences (January 2017-2021), we estimated four binary outcome models to assign patients into complex and standard cases based on the probability of reliable improvement in Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) scores. We evaluated two choices of cut-offs for patient complexity assignment: models at an ROC (receiver operating characteristic)-derived cut-off and a 0.

Are Opioids Agitating? A Data Analysis of Baseline Data from the STAN Study.

 Agitation, a common dementia symptom often arising from untreated pain, lacks comprehensive research on its connection with opioids prescribed for long-term pain. This study investigated the relationship between opioid use and agitation in dementia patients. Participants ( = 188) were categorized into opioid, acetaminophen PRN, or no-pain medication groups.

What Psychiatrists Should Know About Prescribed Safer Opioid Supply.

What Psychiatrists Should Know About Prescribed Safer Opioid Supply.

Key Considerations for the Design, Development and Deployment of AgeTech Solutions Supporting Aging in the Right Place.

"The use of technology to support AIRP [aging in the right place] holds great promise," (Kokorelias et al. 2024: 16) and ethical and human rights considerations must be considered in the design, development and deployment of AgeTech solutions. This may be realized through interprofessional and intersectoral collaboration, as well as meaningful inclusion and engagement of lived expertise and experience from older adults and their caregivers.

Demographic and temporal trends in mental health and substance use services provided by primary care physicians in British Columbia, Canada.

Background: As the demand for mental health and substance use (MHSU) services increases, there will be an even greater need for health human resources to deliver this care. This study investigates how family physicians' (FP) contact volume, and more specifically, MHSU contact volume, is shaped by demographic trends among FPs in British Columbia, Canada.

Methods: We used annual physician-level administrative billing data and demographic information on FPs in British Columbia between 1996 and 2017.

User Experience Testing of the Meta Quest 2 for Integration With the Virtual Reality Simulation for Dementia Coaching, Advocacy, Respite, Education, Relationship, and Simulation (VR-SIM CARERS) Program.

Caregivers (CGs) of persons with dementia (PWDs) face numerous challenges, including learning about the condition, managing behavioral symptoms, and prioritizing their own well-being. Virtual reality (VR) technology has emerged as a promising tool to adopt certain elements of existing CG psychoeducation programs, such as the Reitman Centre CARERS (coaching, advocacy, respite, education, relationship, and simulation) program, which has been shown effective in reducing CG burden and stress and building the required skills for caring for PWD. Recently, we have developed a VR prototype utilizing Meta Quest 2 (Meta, Menlo Park, CA, USA), which will be referred to as the (virtual reality simulation for dementia CARERS) VR-SIM CARERS program.

Use of Virtual Reality and Augmented Reality Technologies to Support Resilience and Skill-Building in Caregivers of Persons With Dementia: A Scoping Review.

Dementia presents a growing public health challenge with most affected individuals living at home, placing significant responsibility on their caregivers. Various interventions, from traditional support groups and education programs to emerging technologies, and more specifically virtual reality (VR) and augmented reality (AR), aim to enhance caregiver skills. While VR/AR shows promise in educating and fostering empathy among caregivers and healthcare professionals, its overall effectiveness and practicality in older adults and dementia care warrant further exploration.

Ketamine in the effective management of chronic pain, depression, and posttraumatic stress disorder for Veterans: A meta-analysis and systematic review.

Introduction: Ketamine has emerged as a promising treatment alternative for the management of chronic pain. Despite encouraging findings in civilian populations, and favourable results from trials examining its efficacy in military populations, there is still a dearth of information pointing to optimal specifications related to ketamine administration for pain, depression, and posttraumatic stress disorder (PTSD) in military populations. This meta-analysis and systematic review synthesised available evidence on the effectiveness, tolerability, and feasibility of ketamine in the management of chronic pain and mental health conditions in military populations.

Transcranial direct current stimulation over medial prefrontal cortex reduced alpha power and functional connectivity during somatic but not semantic self-referential processing.

Past self-report and cognitive-behavioural studies of the effects of transcranial direct current stimulation (tDCS) targeting the medial prefrontal cortex (mPFC) on semantic self-referential processing (SRP) have yielded mixed results. Meanwhile, electroencephalography (EEG) studies show that alpha oscillation (8-12 Hz) may be involved during both semantic and somatic SRP, although the effect of tDCS on alpha-EEG during SRP remains unknown. The current study assessed the EEG and subjective effects of 2 mA tDCS over the mPFC while participants were SRP either on semantic (life roles, e.

Predicting CBT modality, treatment participation, and reliable improvements for individuals with anxiety and depression in a specialized mental health centre: a retrospective population-based cohort study.

Background: Cognitive Behaviour Therapy (CBT) is one of the most successful therapeutic approaches for treating anxiety and depression. Clinical trials show that for some clients, internet-based CBT (eCBT) is as effective as other CBT delivery modes. However, the fidelity of these effects may be weakened in real-world settings where clients and providers have the freedom to choose a CBT delivery mode and switch treatments at any time.

Prevalence of problematic psychological symptoms in samples of Canadian postsecondary students.

Objectives: To estimate the one-month prevalence of problematic psychological symptoms among Canadian postsecondary students, and to compare the prevalence by student characteristics.

Participants: Three samples of students from two postsecondary institutions.

Methods: In a cross-sectional study conducted in 2017, we measured self-reported problems related to symptoms of depression, anxiety, and stress using questions from the functioning module of the WHO Model Disability Survey.

We-Care-Well: exploring the personal recovery of mental health caregivers through Participatory Action Research.

Family caregivers play a critical role in supporting the recovery journeys of their loved ones, yet the recovery journeys of family caregivers have not been well-explored. Using a Participatory Action Research approach, we explore the personal recovery journeys of family caregivers for individuals with mental illness. This case study involved piloting and exploring the impact of a novel online workshop series offered to mental health caregivers at Ontario Shores Center for Mental Health Sciences.

Long-term neuropsychiatric complications of aneurysmal subarachnoid hemorrhage: a narrative review.

This review focuses on the often-neglected long-term neuropsychiatric consequences of aneurysmal subarachnoid hemorrhage (aSAH), beyond traditional randomized trial outcomes of mortality and retreatment. While current guidelines recommend screening for these sequalae, it may not be routinely practiced. This review will underscore the prevalence and management of common neuropsychiatric sequalae, including anxiety, depression, cognitive dysfunction, headaches, seizures, and sexual dysfunction, all of which can significantly impact the quality of life of survivors of aSAH.

Depression, anxiety, and personal recovery outcomes after group vs individual transdiagnostic therapy: a brief report.

Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) is an evidence-informed treatment utilizing Cognitive Behavioural Therapy (CBT) treatment principles. UP has demonstrated promising treatment effects comparable to single disorder protocol across several mental disorders. Its impact on personal recovery in anxiety and depression has not been examined.

Challenges in Promoting Health Equity and Reducing Disparities in Access Across New and Established Technologies.

Medical innovations and novel technologies stand to improve the return on high levels of health spending in developed countries, particularly in cardiovascular care. However, cardiac innovations also disrupt the landscape of accessing care, potentially creating disparities in who has access to novel and extant technologies. These disparities might disproportionately harm vulnerable groups, including those whose nonmedical conditions-including social determinants of health-inhibit timely access to diagnoses, referrals, and interventions.

rTMS for post-covid-19 condition: A sham-controlled case series involving iTBS-300 and iTBS-600.

Post-Covid-19 Condition (PCC) is a syndrome comprised of symptoms persisting 3 months or more beyond SARS-CoV-2 primary infection. It is typically characterized by fatigue, cognitive problems and psychiatric symptoms, as well as cardiac symptoms that contribute to exercise intolerance in many. Despite the high prevalence of PCC among those with a prior SARS-CoV-2 infection, there is currently no widely accepted rehabilitation strategy, and many conventional modalities are movement-based.