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Therapeutic effect of magnesium sulphate on carbon monoxide toxicity-mediated brain lipid peroxidation.
Eur Rev Med Pharmacol Sci
February 2013
Department of Emergency Medicine, Ondokuz Mayis University of Medical School, Samsun, Turkey.
Background: Carbon monoxide (CO) toxicity primarily results from cellular hypoxia caused by impedance of oxygen delivery. Studies show that CO may cause brain lipid peroxidation and leukocyte-mediated inflammatory changes in the brain.
Aim: The aim of this study was to investigate whether magnesium sulphate could prevent or diminish brain lipid peroxidation caused by carbon monoxide toxicity in rats.