1 results match your criteria: "Oncology Research Center CIO-FUCA[Affiliation]"
High neutrophil to lymphocyte ratio and decreased CD69NK cells represent a phenotype of high risk in early-stage breast cancer patients.
Onco Targets Ther
May 2018
Oncology Research Center CIO-FUCA, Buenos Aires, Argentina.
Article Synopsis
- Breast cancer shows significant variation in clinical and molecular traits, making immune response a critical factor in patient outcomes, though immune prognostic markers lack full validation for clinical use.
- A study analyzed immune features in the blood of 85 nonmetastatic breast cancer patients at diagnosis, revealing increased lymphocyte counts in nonrelapsed patients and a high neutrophil-to-lymphocyte ratio linked to better disease-free survival.
- The findings support the idea of immune surveillance and suggest an "immune phenotype" that could aid in prognosis and treatment decisions for early-stage breast cancer patients.