Under-reporting of subjective symptoms and its prognostic value: a pooled analysis of 12 cancer clinical trials.

Background: Oncologists tend to under-report subjective symptoms during cancer treatment. This study describes the under-reporting rate of selected symptoms and explores its association with overall survival (OS). A secondary aim is to test the association of patient-reported symptoms with OS.

[Precision medicine in oncology: what contribution to clinical practice?].

The concept of precision medicine refers to strategies that are designed to provide prevention and treatment based on the characteristics of each patient and the disease. One of the fields where the process of personalization has been very successful is oncology. The path between theory and clinical practice is, however, long and might be shortened by switching methodology, diagnostics, data collection and analysis, and placing a focus on patient-centered care.