[Efficacy of medicamentous treatment of transient premenstrual phlebopathy of lower limbs].

Aim: The purpose of the study was to examine changes of the clinical pattern and the great saphenous vein in women with premenstrual leg heaviness and distal oedema in repetitive 15-day courses of micronized purified flavonoid fraction, initiated in the second half of the menstrual cycle.

Patients And Methods: A total of 39 parous women (mean age 31.3±7.

Biochemical Markers of Saliva in Lung Cancer: Diagnostic and Prognostic Perspectives.

The aim of the work is to study the metabolic characteristics of saliva in lung cancer for use in early diagnosis and determining the prognosis of the disease. The patient group included 425 lung cancer patients, 168 patients with non-cancerous lung diseases, and 550 healthy volunteers. Saliva samples were collected from all participants in the experiment before treatment and 34 biochemical saliva parameters were determined.

Comparative Analysis of the Reproduction Accuracy of Main Methods for Finding the Mandible Position in the Centric Relation Using Digital Research Method. Comparison between Analog-to-Digital and Digital Methods: A Preliminary Report.

: To compare the aspect of the reproduction accuracy in studied methods of determination of the (CR) of jaws using the digital research methods. The methods used were bilateral manipulation by P.E.

[Improvement of performance of semen culture in infertile men undergone to diagnostic evaluation].

Introduction: Barren marriage is an important medical and social problem. Up to 20-60% of cases of male infertility are associated with inflammatory diseases of the reproductive system. Chronic prostatitis constitutes up to 50% cases.

[A comparative analysis of reproducibility of the jaws centric relation determined with the use of digital technologies].

Aim: To compare the precision of centric relation (CR) assessment by various methods using digital technologies.

Material And Methods: Determination of the CR was carried out in the clinic of prosthetic dentistry on patients with intact dentition using methods of bilateral manipulation, anterior jig, leaf gauge and device for intraoral recording of the gothic arch angle. Optical jaw impressions were obtained using the intraoral 3D scanner Trios (3Shape) and the CR registers were scanned using the laboratory scanner Prime (DOF).

[Immunological markers of defeat of nervous tissue as an element of predictive model of damage of nervous system at syphilis.].

To develop predictive model of damage of nervous system on the basis of definition of concentration of interleukins-23, 12p40 and also a glial fibrillar acid protein (GFAP) in liquor of patients with various forms of syphilis. Comprehensive laboratory examination of patients with neurosyphilis and syphilis without specific damage of nervous system who were observed in venereologic office of BOUZAS of OO «Clinical Dermatovenerologic Clinic» of Omsk is conducted. To all patients were carried out: a serological blood analysis, serological and clinical trial of liquor, and also immunological research of liquor (interleukins - 23, 12p40, and also GFAP).

Placental blood flow and pregnancy outcomes in women with abnormal placental localization and absence of placental "migration".

Aim: We investigated the arcuate artery blood flow in the region of the abnormally localized placenta in women who had undergone insertion of an obstetric pessary and were receiving micronized progesterone.

Materials And Methods: The study included 120 pregnant women with high perinatal risks and abnormal placental localization. The patients were randomized to receive the Arabin's pessary and vaginal micronized progesterone (Group A,  = 60) or vaginal micronized progesterone only (Group B,  = 60).

[Provision of vitamin D in the adult population of Western Siberia: a population-based study].

The results of research in recent years indicate a widespread low intake of vitamin D, its deficiency or lack among the population of many countries around the world. It is of interest to study vitamin D status of the population living at different geographic latitudes and depending on socio-demographic characteristics. of the research is to analyze vitamin D status of the adult population living in the Omsk Region over the age of 18 in different seasons of the year.

[Possibilities of serological verification of siberian tick borne type with use of test system for identification of antibodies to Rickettsia conorii.].

The real epidemiological impact of Spotted Fever Group rickettsioses including Siberian tick-borne typhus (STT) in Russia is not sufficiently studied. One of the reasons is the actual absence of either certified domestic diagnostic kits or the evidence for using foreign test kits for laboratory verification of this group of tick-borne infections in medical practice. Objective of our study was to study the diagnostic accuracy of the ELISA test system based on Rickettsia conorii antigens for serological verification of STT.

The use of an osmotic dilator for induction of miscarriage in patients with the second trimester missed miscarriage.

Aim: The aim of this study was to assess the outcomes of combined use of dilapan-S and pharmacological induction of miscarriage with mifepristone and misoprostol versus mifepristone and misoprostol only in patients with a second-trimester pregnancy loss.

Materials And Methods: Our study included 74 patients with a second-trimester antenatal death who were randomized into two groups to receive pharmacological induction of miscarriage combined with intracervical insertion of dilapan-S ( = 37) or pharmacological induction of miscarriage only ( = 37). Efficacy endpoints included: blood loss volume, length of time between the procedure initiation and complete miscarriage, and the number of complications.

A fatal case of tick-borne rickettsiosis caused by mixed Rickettsia sibirica subsp. sibirica and "Candidatus Rickettsia tarasevichiae" infection in Russia.

North Asian tick-typhus (NATT), also known as Siberian tick typhus, is the main tick-borne rickettsiosis in Siberia, Russia. Recently, a fatal infection in a four-year-old girl with typical tick-borne rickettsiosis symptoms (fever, rash, eschar at the site of the tick bite, myalgia) and meningeal syndrome was registered. In order to identify the etiology of this infection, blood and brain samples from the patient were examined for the presence of a wide range of tick-transmitted agents and enteric viruses by polymerase chain reaction with subsequent sequencing.

Improvement of Orthopedic Residency Programs and Diversity: Dilemmas and Challenges, an International Perspective.

Background: To date, little has been published comparing the structure and requirements of orthopedic training programs across multiple countries. The goal of this study was to summarize and compare the characteristics of orthopedic training programs in the U.S.

Analysis of risk factors and predictors of pregnancy loss and strategies for the management of cervical insufficiency in pregnant women at a high risk of preterm birth.

Aim: To identify risk factors and predictors of pregnancy loss and to compare the efficacy of Arabin's pessary with cervical cerclage in women at a high risk of pregnancy loss.

Materials And Methods: This was a two-center retrospective case-control study that included 240 women at a high risk of preterm delivery. Group I ( = 161) included women who underwent insertion of the Arabin's pessary between 14 and 24 weeks of pregnancy.

[The role of school dental service in the decrease of oral pathology in Omsk pediatric population].

The aim of the study is to analyze the oral health of school-aged children in Omsk in schools with and without dental service and to assess the efficacy of school dental service for the prevention of oral diseases. In 2016-2017 1103 12 and 15-years old were examined in school with dental service functioning for 15 years and in one with the absence of dental service for the last 21 years. The study revealed lack of preventive approach in school dental service.

[An influence of the modified therapy on the course of epilepsy in patients with the low cerebral spinal fluid-cranial index].

Aim: To evaluate the effect of modified therapy on the course of epilepsy in patients with the low cerebral-spinal-fluid-cranial (CSF-cranial) index.

Material And Methods: One hundred and twenty-four patients with cryptogenic epilepsy were prospectively analyzed. Group I consisted of 36 patients with a normal volume of reserve cerebrospinal fluid and a level of the CSF-cranial index within the physiological norm (from 1.

[Clinical aspect of diagnostics of gastroesophageal reflux disease in elderly patients.].

Insufficient knowledge age peculiarities of gastroesophageal reflux disease (GERD) in the elderly against the background of its prevalence determine the high demand for studies on the topic. In an open study cohort by cross-sectional analysis was conducted clinical features GERD patients older age groups. By continuous sampling of 90 patients taken away: the main group - 45 persons 60-86, comparison group - 45 persons 25-59 years.

[Use of scanning electron microscopy to study Candida albicans biofilms on the surface of base plastics of removable orthopedic constructions.].

The most common pathology in the clinic of orthopedic dentistry is the presence of partial adentia in patients, manifested in the form of defects of dentition of various localization and length. Removable orthopedic structures in the oral cavity are a potential place for adhesion and colonization of microorganisms. The aim of the research was to study Candida albicans biofilms on the surface of base plastics of removable orthopedic structures using scanning electron microscopy.

[The processes of lipoperoxidation and endogenous intoxication in saliva in central and peripheral lung cancer.].

The aim of the study was to establish the patterns of changes in the parameters of endogenous intoxication and lipoperoxidation processes in the saliva of patients with lung cancer, depending on the form of tumor growth (central, peripheral or mediastinal cancer). Materials and methods: in the case - control study was attended by 562 volunteers, who were divided into 2 groups: main (lung cancer, n = 347) and control group (relatively healthy, n = 2015). Questioning, biochemical saliva study and histological verification of the diagnosis carried out to all participants.

[Giant complicated duodenal ulcer in patient with diabetes mellitus].

Treatment of complicated giant duodenal ulcers is one of the most difficult problems in abdominal surgery. Simultaneous course of diabetes mellitus and giant duodenal ulcer has clinical features and requires correction of the treatment. It is presented case report that may be useful regarding accumulation of knowledge about comorbid course of these pathologies.

Role of intestinal microbiota in the formation of non-alcoholic fatty liver disease.

The article provides an overview of modern views on the role of intestinal microbiota in the formation of non-alcoholic fatty liver disease. The general questions of the pathogenesis of the syndrome of excessive bacterial growth in the intestine, the participation of opportunistic microflora, the deficit of representatives of normal microflora, changes in the species composition of bile acids in the pathogenesis of nonalcoholic fatty liver disease are considered.

Clinically significant food preferences of patients with atrial fibrillation: a nosological and regional peculiarities.

Aim: The aim of the investigation was to study the peculiarities of food consumption in patients with atrial fibrillation, capable of influencing the anticoagulant therapy with warfarin, in comparison with healthy volunteers and taking into account geographical specifics.

Materials And Methods: In an open cohort study, 196 respondents (88 men, 108 women) evaluated food preferences using a questionnaire survey. The quantitative evaluation of adherence to lifestyle modification was studied by QAA-25.

Simple Assay for Detection of the Central Asia Outbreak Clade of the Mycobacterium tuberculosis Beijing Genotype.

The Central Asia outbreak (CAO) clade is a branch of the Beijing genotype that is associated with multidrug resistance, increased transmissibility, and epidemic spread in parts of the former Soviet Union. Furthermore, migration flows bring these strains far beyond their areas of origin. We aimed to find a specific molecular marker of the Beijing CAO clade and develop a simple and affordable method for its detection.

[Interleukins - 23, -12p40 as markers of neural tissue damage in neurosyphilis.].

To study the features of cytokines in patients with various forms of neurosyphilis. The complex laboratory examination of patients with neurosyphilis and syphilis without specific lesion of the nervous system was observed in the venereological department of the OSH "Clinical Dermatological and Venereological Dispensary" in Omsk in order to determine the concentration of interleukins - 23, 12p40 in CSF and assess their relationship with the course of syphilitic infection. The presence of regularities and features in the deviation of the immune status in the examined disease was established.