Evaluating data sharing statements in leading emergency medicine journals: A mixed methods review.

Background: Emergency medicine remains as the front line of healthcare, providing acute care to a diverse population during urgent and critical moments. Our objective was to systematically quantify the prevalence of data sharing statements (DSS) in high-impact emergency medicine journals and assess their implementation by contacting corresponding authors who indicated data available upon request.

Methods: We conducted a cross-sectional analysis to identify the prevalence and content of data sharing statements in clinical studies published in high impact emergency medicine journals between 2018 and 2023, followed by a hierarchical logistic regression analysis to identify variables impacting the incorporation of data sharing statements into emergency medicine studies.

Prevalence of Diabetic Retinopathy and Dilated Fundus Examinations by Metropolitan Status from 2017-2021: An Assessment of the Behavioral Risk Factor Surveillance System.

Purpose: Diabetic eye disease, namely diabetic retinopathy (DR), remains a leading cause of preventable blindness worldwide. Research has shown that treatment for diabetes and eye care was disrupted during the pandemic - with disparities between urban and rural populations being unknown. Thus, we aimed to assess the prevalence of reported rates of DR and dilated fundus exams from 2017 to 2021.

Assessing the Quality of Social Media Content Regarding Facial Paralysis and Reanimation.

Patients frequently use social media to direct their health care. However, the quality of social media posts regarding facial paralysis and reanimation is unclear. To assess the quality of facial reanimation posts on social media.

Primary Cutaneous Rhabdoid Squamous Cell Carcinoma: A Case Report and Review of Molecular Features.

We present a rare case of rhabdoid squamous cell carcinoma (RSCC) on the scalp of a non-immunosuppressed male patient in his late 60s. This aggressive variant of squamous cell carcinoma (SCC) is characterized by tumor cells with eccentrically located nuclei and abundant eosinophilic cytoplasm, as observed on histopathological examination. While rhabdoid morphology has been reported in various anatomical sites, its occurrence in primary cutaneous tumors is exceptionally uncommon, with fewer than 10 cases documented to date.

The Role of Pregnancy Intentions in U.S. Women's Contraceptive and Alcohol Use Behaviors.

Background: Alcohol use in early pregnancy increases the risk for Fetal Alcohol Spectrum Disorders. Women who engage in heavy drinking and become pregnant when they are not actively trying to conceive are at heightened risk for alcohol-exposed pregnancies. Identifying factors associated with greater risk for alcohol-exposed pregnancies is critical for prevention.

Pseudosuchia: Masters of survival and diversification.

In the context of an increasing interest for Pseudosuchia, we have compiled a Special Issue, comprising 14 collaborative studies that deepen our understanding of pseudosuchian evolution. These contributions range from the description of a new taxon to exhaustive reviews of thermometabolism, morphological adaptation, systematics, and detailed investigations into ontogeny, paleoneurology, paleohistology, and paleobiology. Through these papers, we explore the evolutionary history of pseudosuchian archosaurs, spotlighting their rise and diversification following the end-Permian mass extinction.

Characteristics and Outcomes of Patients With a Moderate History, ECG, Age, Risk Factors, and Troponin (HEART) Score.

Introduction Chest pain is a common, expensive cause of admission to the hospital from the Emergency Department (ED). The History, ECG, Age, Risk Factors, and Troponin (HEART) score is a risk stratification tool often used to determine the disposition of chest pain patients. This study evaluates the association of age, gender, HEART score, diabetes mellitus (DM), hypertension (HTN), hypercholesterolemia, family history (Fam Hx), and tobacco use with major adverse cardiovascular events (MACE) and hospital readmission.

Gaps and opportunities for measuring equity with the Translational Science Benefits Model: Recommendations from the Center for American Indian and Alaska Native Diabetes Translation Research.

Translational research needs to show value through impact on measures that matter to the public, including health and societal benefits. To this end, the Translational Science Benefits Model (TSBM) identified four categories of impact: Clinical, Community, Economic, and Policy. However, TSBM offers limited guidance on how these areas of impact relate to equity.

Assessing the completeness of patient-reported outcomes reporting in congestive heart failure clinical trials.

Objective: We aim to evaluate the quality of patient-reported outcomes included in randomized control trials for the treatment of congestive heart failure using the International Society for Quality of Life Research (ISOQOL) checklist, a validated tool for critically appraising the quality of patient-reported outcomes.

Design: We performed a cross-sectional analysis of 65 randomized control trials with patient-reported outcomes for drug intervention trials for treating congestive heart failure.

Setting: N/A.

Community-Engaged Development of a Nutrition Curriculum: The Go Healthy Indigenous-Supported Agriculture Study.

Objective: To understand how Osage Nation community members define healthy eating and develop a corresponding nutrition curriculum through community engagement.

Design: This project comprised a concurrent embedded mixed methods group concept mapping (GCM) study followed by focus group discussions (FGD) to provide feedback on a nutrition curriculum.

Setting: Osage Nation, Oklahoma.

Community-Engaged Development of Strengths-Based Nutrition Measures: The Indigenous Nourishment Scales.

Mainstream approaches to nutrition typically focus on diet consumption, overlooking multi-dimensional aspects of nutrition that are important to American Indian/Alaska Native (AI/AN) communities. To address health challenges faced by AI/AN communities, strengths-based measures of nutrition grounded in community worldviews are needed. In collaboration with AI/AN communities in Baltimore and Minneapolis, we developed the Indigenous Nourishment Scales through three phases.

Recruitment and Retention Strategies for Historically Marginalized Populations in Colorectal Cancer Trials: A Cross-Sectional Analysis Using Systematic Review Methods.

Purpose: Colorectal cancer (CRC), a leading cause of cancer mortality, disproportionately impacts historically marginalized populations due to persistent health inequities. Effective recruitment and retention strategies are crucial to improving the representation of these populations in clinical trials. This study aims to evaluate the use of recruitment and retention strategies in CRC clinical trials, their impact on participant diversity, and the presence of diversity recruitment goals and ethical considerations.

Myxofibrosarcoma-Like Spindle Cell Squamous Cell Carcinoma of the Scalp: A Rare Mimic.

We report a challenging case of a man in his mid-70s diagnosed with a myxofibrosarcoma-like spindle cell squamous cell carcinoma (ML-SCC) on the scalp. This rare tumor shares cytologic features with spindle cell squamous cell carcinoma (SCC) with myxoid characteristics but also exhibits architectural elements typical of myxofibrosarcoma, making it nearly indistinguishable by routine light microscopic evaluation. Myxoid spindle cell carcinomas are exceptionally rare, and only one case of ML-SCC has been previously documented in the peer-reviewed medical literature.

Preference signaling in orthopaedic surgery: applicant perspectives and opinions.

Context: Orthopaedic surgery has become increasingly competitive over the years, with the COVID-19 pandemic creating additional challenges for applicants and programs. To promote an equitable match experience, the American Orthopaedic Association (AOA) introduced a formal preference signaling (PS) system into the 2022-2023 application cycle. PS allows applicants to indicate their heightened interest in specific programs, which improves the likelihood of receiving an interview and ultimately matching at their desired residency program.

Nuclear factor kappa-B cell (NF-κB), interferon regulatory Factor, and glucocorticoid receptor pathway activation in major depressive Disorder: The role of cytomegalovirus infection.

Altered activity of major immunoregulatory pathways has been reported in major depressive disorder (MDD) and is thought to underlie the elevations in circulating inflammatory mediators present in a subgroup of patients. However, the drivers of these changes in gene expression remain unclear. One potential modulator of immune function is viral infection.

Assessing the Uptake of the Lung Cancer Core Outcome Set: A Cross-Sectional Analysis.

Introduction: A core outcome set (COS) helps standardize outcome measurements across clinical trials. Although lung cancer is the leading cause of cancer-related deaths, research exploring COS implementation across lung cancer trials remains limited. We aim to analyze the uptake of the lung cancer COS and identify potential gaps in COS adherence.

US Public Interest in Merkel Cell Carcinoma Following Jimmy Buffett's Death and Implications for Continued Health Advocacy: Infodemiology Study of Google Trends.

Through Jimmy Buffett's unfortunate battle with lymphoma originating from Merkel cell carcinoma and subsequent media coverage of his death, public interest in skin cancer, Merkel cell carcinoma, and the health effects of sunlight exposure increased, as evidenced by our results.

Improving peripheral artery disease screening and treatment: a screening, diagnosis, and treatment tool for use across multiple care settings.

Peripheral artery disease (PAD) is an atherosclerotic disease that contributes to significant morbidity and mortality, including loss of limb, myocardial infarction (MI), stroke, and death. Treatment options are often underutilized. A major limiting factor in PAD care is the ability to efficiently identify and screen at-risk patients.

Exploring the Association Between Minimum Wage Policy, Income Inequality, and Obesity Rates in US Counties.

Objective: To examine the interaction between minimum wage policy, income inequality, and obesity rates among U.S. counties, and how this relationship is shaped by policy, place, and racial/ethnic composition in a county.

Treatment in persistent genital arousal disorder: a scoping review.

Background: Persistent genital arousal disorder (PGAD) is a rare condition characterized by unwanted and distressing symptoms of arousal and dysesthesia. The aim of this scoping review was to map the current state of PGAD management, identify gaps in the literature, and understand patient perspectives.

Methods: We completed a scoping review following guidelines from the Joanna Briggs Institute and the Preferred Reporting Items for Systematic Reviews and Meta Analyses Scoping Reviews extension.

Intralesional Talimogene Laherparepvec Immunotherapy for Melanoma: A Case Study.

Melanoma, characterized by its aggressive nature and tendency for metastasis, presents a significant challenge in clinical management. While surgical excision remains the gold standard for localized disease, therapeutic advancements for advanced stages are crucial. Oncolytic virotherapy, exemplified by Talimogene laherparepvec (T-VEC), offers a potential approach.

Craniomandibular variation in the endemic Hispaniolan primate, Antillothrix bernensis.

Here we describe new fossil material of Antillothrix bernensis, a Pleistocene-Holocene primate taxon from Hispaniola. It is now represented by seven crania, five mandibles, and dozens of postcranial elements from several paleontologically rich cave systems. The five adult crania included here share a similar overall profile as well as specific features such as a deep depression at the glabella.

Quantifying brain development in the HEALthy Brain and Child Development (HBCD) Study: The magnetic resonance imaging and spectroscopy protocol.

The HEALthy Brain and Child Development (HBCD) Study, a multi-site prospective longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. The acquisition of multimodal magnetic resonance-based brain development data is central to the study's core protocol. However, application of Magnetic Resonance Imaging (MRI) methods in this population is complicated by technical challenges and difficulties of imaging in early life.