171 results match your criteria: "Okazaki Medical Center[Affiliation]"

Article Synopsis
  • The study aimed to create global benchmark outcome indicators for laparoscopic right posterior sectionectomies (L-RPS/H67) to improve surgical standards.
  • It analyzed data from 854 patients across 57 centers globally, establishing key performance benchmarks for low-risk cases based on specific outcome indicators.
  • The findings set standard benchmarks for metrics like operation time and complication rates, serving as a reference for surgical auditing and improvement.
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Background: There are different definitions of periprocedural myocardial infarction (PPMI) both in terms of thresholds for cardiac biomarkers and the ancillary criteria for myocardial ischemia. Cardiac Troponin I (cTnI) and cardiac Troponin T (cTnT) are used interchangeably to diagnose PPMI.

Objectives: This study evaluated the frequency of periprocedural myocardial injury and infarction as defined by the Society of Cardiovascular Angiography & Interventions (SCAI), the Academic Research Consortium-2 (ARC-2), and the 4th Universal definition of MI (4UDMI) stratified using cTnT versus cTnI, among patients with chronic coronary syndrome (CCS) and unstable angina.

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Currently, human papillomavirus tests and cytology are used to screen for cervical cancer. However, more accurate ancillary screening tests are needed. MicroRNAs (miRNAs) and cytokines are promising biomarkers that are aberrantly expressed in cervical cancer.

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Background: In recent years, there has been growing interest in laparoscopic liver resection (LLR) and the audit of the results of surgical procedures. The aim of this study was to define reference values for LLR in segments 7 and 8.

Study Design: Data on LLR in segments 7 and 8 between January 2000 and December 2020 were collected from 19 expert centers.

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Impact of neoadjuvant chemotherapy on short-term outcomes after simple and complex minimally invasive minor hepatectomy for colorectal liver metastases: A propensity-score matched and coarsened exact matched study.

Eur J Surg Oncol

June 2024

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore; Surgery Academic Clinical Programme, Duke-National University of Singapore Medical School, Singapore. Electronic address:

Article Synopsis
  • Minimally invasive liver surgery has become more common over the last 30 years, especially for treating colorectal liver metastases, but the effects of neoadjuvant chemotherapy on surgical outcomes are not well understood.
  • A study analyzed a large database of nearly 5,000 patients who underwent minimally invasive liver surgeries to compare outcomes between those who received neoadjuvant chemotherapy and those who did not.
  • The results showed that neoadjuvant chemotherapy did not significantly affect the short-term surgical outcomes in patients undergoing these liver procedures.
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Article Synopsis
  • - The study investigated how new lithotomy stirrups (type 2) affect pressure distribution on lower limbs during laparoscopic and robot-assisted rectal surgery, aiming to minimize the risk of well-leg compartment syndrome (WLCS) and deep venous thrombosis (DVT).
  • - Researchers tested 30 participants by measuring pressure on different leg muscles in various positions using both conventional stirrups (type 1) and the new stirrups (type 2) with a specialized sensor.
  • - Results showed that the new stirrups significantly reduced pressure on key leg muscles, particularly shifting from the proximal to the more distal soleus muscle, which may lower the likelihood of WLCS and DVT after surgery; however
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The IMM (Institut Mutualiste Montsouris) difficulty classification for laparoscopic liver resection is based only on the type of surgical procedure. It is useful for assessing outcomes and setting benchmarks in a group sharing the same indications. There is, however, no left medial sectionectomy in the system.

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Article Synopsis
  • * Results showed that the ERAS protocol significantly shortened hospital stays, improved bowel recovery, and reduced POI in non-frail patients, but it did not have the same benefits for frail patients.
  • * The findings suggest that while ERAS is effective for non-frail patients, frail patients might require additional strategies, like prehabilitation, to better manage POI post-surgery.
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Purpose: In the context of in vitro fertilization-embryo transfer (IVF-ET), factors other than egg quality may be key determinants of treatment success, in particular, maternal factors related to uterine endometrial receptivity and unidentified factors. We therefore aimed to analyze the metabolome and microbiome in IVF-ET patients who did and did not achieve pregnancy.

Methods: Cervicovaginal mucus was collected from patients undergoing IVF-ET.

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Background: The ASET (Acetyl-Salicylic Elimination Trial) pilot studies recently investigated P2Y inhibitor monotherapy without aspirin immediately after percutaneous coronary intervention (PCI) in Brazil and Japan.

Objectives: This comparative analysis of the 2 ASET pilot studies aimed to summarize clinical outcomes and assess geographic and ethnic differences in baseline demographics and procedures.

Methods: Patients undergoing successful platinum-chromium everolimus-eluting stent implantation for chronic coronary syndrome were included.

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We encountered a previously healthy 3-year-old girl with interstitial pneumonitis that initially developed due to human adenovirus type 2 infection and exacerbated by primary human herpesvirus 7 infection. A comprehensive serum biomarker analysis showed patterns that differed by viral infection, suggesting that respiratory and lymphotropic viral infections might have different pathophysiology in interstitial pneumonitis.

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Article Synopsis
  • The study aimed to predict the success of nonsurgical treatment, specifically extracorporeal shock wave lithotripsy (ESWL), for removing pancreatic stones in patients and to find the optimal number of treatment sessions needed.
  • Data from 164 patients treated between 1992 and 2020 indicated that 79% achieved total stone clearance, with an average of 3 ESWL sessions, and an optimal threshold of 7 sessions was identified for effective treatment.
  • Results showed that patients who underwent 7 or fewer sessions had a higher clearance rate (87%) compared to those with more sessions (48%), leading to the recommendation to consider other medical or surgical options if stones remain after 7 sessions.
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Article Synopsis
  • *Methods*: Researchers analyzed data from 533 patients who had primary PCI for STEMI, comparing outcomes between those guided by OCT and those guided by intravascular ultrasound (IVUS), using techniques to ensure fair comparisons.
  • *Results*: Although patients in the OCT group were younger and healthier, the two groups had similar rates of serious complications (target lesion failure). However, cardiac deaths were lower in the OCT group compared to the IVUS group, suggesting OCT may be a safer option.
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Article Synopsis
  • - The study explores the link between the use of intrauterine manipulators during laparoscopic hysterectomies and various pathological factors, as well as cancer outcomes in endometrial cancer patients in Japan, analyzing data from 3846 patients between 2015-2017.
  • - Results show that intrauterine manipulator use is correlated with higher incidences of lymphovascular space invasion (17.8% vs. 13.3%) and malignant cells in pelvic peritoneal cytology (10.8% vs. 6.4%), indicating increased risks associated with its use.
  • - Despite the potential risks, the 5-year survival rates were still high (94.2% with manipulator vs.
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Background: Artificial intelligence (AI) is becoming more useful as a decision-making and outcomes predictor tool. We have developed AI models to predict surgical complexity and the postoperative course in laparoscopic liver surgery for segments 7 and 8.

Methods: We included patients with lesions located in segments 7 and 8 operated by minimally invasive liver surgery from an international multi-institutional database.

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Article Synopsis
  • Hydrocele of the canal of Nuck (HCN) is a rare condition, and there's limited understanding of when laparoscopic surgery is needed for it.
  • A case study of a 53-year-old woman showed successful laparoscopic treatment for a hydrocele that extended from her abdominal cavity down to the inguinal area, with the surgery involving dissection and mesh reinforcement.
  • The laparoscopic approach was deemed effective and safe, reducing risks of injury to surrounding blood vessels compared to traditional methods, highlighting its potential benefits for similar cases.
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Approximately 500,000 women are diagnosed with cervical cancer annually, with high-grade cervical intraepithelial neoplasia (CIN) estimated to be 20 times higher. The diathermy ablation is an inexpensive minimally invasive surgeries for CIN. However, little is known about the treatment outcomes.

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Background And Purpose: Tumor embolization through the meningohypophyseal trunk and inferolateral trunk is known to be effective in skull base tumors; however, microcatheter cannulation into these arteries is difficult, and the number of cases that can be safely embolized is limited. In this study, we present a novel embolization procedure for the meningohypophyseal trunk and inferolateral trunk using the distal balloon protection technique and detail its clinical efficacy and complication risks. We developed this procedure to allow safe embolization in patients who cannot be adequately cannulated with microcatheters into these arteries.

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Article Synopsis
  • Intraventricular surgery typically uses a flexible endoscope for aspiration of lesions, but visibility is poor because the lens is close to the working channel.
  • A new technique was developed using an angiographic catheter for better aspiration, allowing for continuous irrigation while maintaining good visibility.
  • This innovative approach improves surgical clarity and minimizes the risk of complications during the procedure.
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Article Synopsis
  • The study investigates the geographical differences in coronary artery disease (CAD) characteristics among patients from Japan and Brazil, focusing on those undergoing percutaneous coronary intervention (PCI).
  • Results show that Japanese patients had more significant functional stenoses and lower post-PCI flow ratios compared to Brazilian patients, indicating a disparity in CAD patterns between the two regions.
  • The findings suggest that assessing both pre-procedural physiological indices and the diffuseness of CAD can help identify patients who may benefit most from PCI, highlighting the importance of tailored treatment approaches.
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Article Synopsis
  • The study aimed to assess the safety and effectiveness of robot-assisted radical cystectomy with an intracorporeal ileal conduit in older patients (≥75 years) compared to younger patients (<75 years).
  • A total of 122 patients were analyzed, showing no major differences in perioperative outcomes except for a longer hospital stay for older patients (19 days vs. 16 days).
  • Despite some complications being more frequent in older patients, there were no significant differences in cancer recurrence or survival rates, suggesting that the procedure is safe and effective for older individuals.
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The renal angina index (RAI) is a validated scoring tool for predicting acute kidney injury (AKI). We investigated the efficacy of the RAI in 2436 heterogeneous patients (mean age, 70 years) treated in cardiac intensive care units (CICUs). The RAI was calculated from creatinine and patient condition scores.

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