358 results match your criteria: "Okazaki City Hospital[Affiliation]"

The patient is an 81-year-old man. He underwent surgery for pancreatic body cancer in 201X and was followed up every six months with computed tomography (CT) imaging. A CT scan in 201X+5 showed a new nodule in S6 of the right lung.

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A 70-year-old man presented with the growth of an anterior mediastinal nodule on a follow-up computed tomography (CT) scan after undergoing lung cancer surgery. Positron emission tomography (PET)-CT performed at the time of lung cancer surgery did not recognize any accumulation, but PET-CT performed this time confirmed the accumulation of standardized uptake value( SUV) max 5.57.

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Background: The accumulation of ascites is a major symptom of ovarian cancer. The volume of ascites is a pathophysiological indicator of the peritoneal environment, such as inflammation and fibrosis; however, the relationship between the volume of ascites and oncological outcomes remains unclear. We herein retrospectively examined the effects of the volume of ascites on the prognosis of epithelial ovarian cancer in a multi-institutional large cohort using the stratification of clinical characteristics and statistical adjustment methods.

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Artificial intelligence for ultrasound scanning in regional anesthesia is a rapidly developing interdisciplinary field. This study aimed to evaluate the efficacy of computer-aided three-dimensional ultrasound (C-aided US) guidance for neuraxial anesthesia in adult patients. We searched all randomized controlled trials (RCTs) of adult patients who required neuraxial anesthesia in the MEDLINE, CENTRAL, Embase, International Clinical Trials Registry Platform (ICTRP), and ClinicalTrials.

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Purpose: Polycystic ovary syndrome (PCOS) significantly affects women. This study investigated the association between serum anti-Müllerian hormone (AMH) levels and menstrual cycle disorders, and AMH for PCOS in a general cohort of young Japanese women.

Methods: We measured serum AMH levels in 528 healthy female students at two universities in Japan between 2014 and 2020.

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Background: In bronchoplasty of wedge resections, it is necessary to transect the bronchus at a sharp angle and depth. As a result, anastomoses after wedge resections have the disadvantages of poor visibility and operability. Here, we report a case of right wedge-shaped sleeve bilobectomy that was successfully performed with continuous knotless suturing using robotic assistance.

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  • The new Japanese guidelines for primary aldosteronism introduce a "borderline range" for functional confirmatory tests, which is not commonly found in other international guidelines.
  • This study compared patients in the borderline group to definitive-positive and negative groups using data from a nationwide Japanese registry, analyzing results from 1,785 individuals based on their captopril-challenge test results.
  • The findings showed that the borderline group did not differ significantly from the negative group concerning target organ damage, though both groups had higher odds of chronic kidney disease and electrocardiographic abnormalities when compared to definitive-positive patients.
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  • * The research involved a multicenter point-prevalence survey of 10,199 patients across 27 hospitals in Aichi Prefecture, revealing a 6.6% rate of HAIs, with pneumonia, urinary tract infections, and surgical site infections being the most common.
  • * The study concludes that the findings are crucial for understanding HAIs in Japan and stresses the importance of national-level surveys to monitor healthcare challenges, especially in the context of post-COVID-19 conditions.
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Introduction: Most cases of squamous cell carcinoma (SCC) of the tongue occur on the lateral surface; however, SCC of the dorsum is extremely rare.

Case Presentation: The authors describe the case of a 79-year-old man with SCC involving the midline of the dorsum of the tongue. The lesion was surgically resected.

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  • * Surgical removal of the torus improved her tongue movement and pronunciation, with a follow-up showing no recurrence after 6 months.
  • * The study highlights the effectiveness of surgical intervention for speech issues caused by torus, and it uniquely utilizes 3D-CT imaging for analysis in this context.
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  • - The study developed a novel method for detecting circulating tumor cells (CTCs) and analyzing EGFR mutations specifically in lung cancer patients, using a new immunocytology platform.
  • - A pilot study with 33 patients revealed that CTC levels were significantly higher in pulmonary blood samples compared to peripheral blood, and the genetic analysis of CTCs revealed several EGFR mutations that were often consistent with mutations found in lung tissue.
  • - The findings suggest that this new CTC detection method could serve as a useful liquid biopsy tool for monitoring lung cancer in clinical settings, although it showed some limitations in mutation sensitivity.
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Objective: There is no consensus on the optimal treatment for patients with locoregional recurrence of esophageal cancer after surgery. The objective of this study was to investigate the outcomes and prognostic factors associated with salvage radiotherapy in patients with locoregional recurrence of esophageal cancer after surgery.

Methods: We reviewed 80 patients with locoregional recurrence of esophageal cancer after surgery who were treated with radiotherapy.

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  • * An analysis of 3,575 patients showed that type 4 tumors had significantly lower overall survival rates compared to large type 3 tumors, but when comparing large type 3 undifferentiated tumors to type 4, their outcomes were similar.
  • * The findings suggest that large type 3 tumors with an undifferentiated phenotype and type 4 tumors may be treated as a new category in future clinical trials, highlighting the need for more specific classifications.
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Ultrasound-guided clavipectoral fascial plane block (CPB) and intermediate cervical plexus block (ICPB) have been used as novel approaches for clavicular fracture surgery in adults. However, there are few reports of ultrasound-guided CPB combined with ICPB for clavicular surgery in children under 18 years of age. A 16-year-old male baseball player (weight, 57 kg; height, 160 cm) was scheduled to undergo open reduction and internal fixation with superior plate placement for a left-sided displaced midshaft clavicular fracture.

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Background: Nuclear protein in testis (NUT) carcinoma (NC) of the lung is a rare cancer that occurs mainly in young adolescents and adults. NC is genetically characterized by rearrangements, which usually take the form of fusions. The prognosis for NC is dismal, and treatment with conventional chemotherapeutic regimens is ineffective.

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Purpose: Non-previa placenta accreta spectrum (PAS) is associated with assisted reproductive technology (ART), particularly frozen embryo transfer during hormone replacement therapy (HRC-FET). We especially aimed to evaluate the prevalence and risk factors for non-previa PAS in HRC-FET pregnancies.

Methods: Overall, 279 women who conceived through ART at three ART facilities and delivered at a single center were included in this retrospective study.

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  • The study aimed to compare the postoperative quality of life (QOL) and body weight changes between two types of gastrectomies: pylorus-preserving gastrectomy (PPG) and distal gastrectomy (DG) for Stage I gastric cancer.
  • Conducted on 295 patients, the research utilized questionnaires to assess QOL and found that DG had better scores for nausea, vomiting, and meal-related issues in the first month after surgery.
  • Ultimately, the study concluded there was no significant difference in long-term QOL or body weight loss between the two surgical methods.
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  • The study examines the safety and effectiveness of robot-assisted pelvic exenteration (RPE) in comparison to open pelvic exenteration (OPE) and conventional laparoscopic pelvic exenteration (LPE) for treating pelvic cancer.
  • A multicenter retrospective analysis included 261 patients from January 2012 to October 2022, and the results showed that RPE led to significantly less blood loss and lower transfusion rates compared to OPE.
  • RPE also demonstrated a lower complication rate compared to both OPE and LPE, indicating it may be a preferable option for patients with advanced pelvic tumors.
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  • - The study investigates how responses to auditory stimuli are influenced by prior stimuli using two measures: paired-pulse suppression (PPS) and prepulse inhibition (PPI), highlighting their roles in various diseases, particularly schizophrenia and Alzheimer's.
  • - Normative data were collected from healthy participants (35 females and 32 males, aged 19-70) to analyze the effects of age and sex on PPS and PPI values, with specific auditory stimuli tested via electroencephalography.
  • - Results indicated females exhibited stronger test responses but weaker inhibition across both measures; aging was associated with stronger responses and weaker inhibition in PPS, but not in PPI, suggesting that age and sex should be considered in future studies involving these auditory processing mechanisms
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We compared survival outcomes of high-dose concomitant boost radiotherapy (HDCBRT) and conventional dose radiotherapy (CRT) for newly diagnosed glioblastoma (GB). Patients treated with intensity-modulated radiation therapy for newly diagnosed GB were included. In HDCBRT, specific targets received 69, 60, and 51 Gy in 30 fractions, while 60 Gy in 30 fractions was administered with a standard radiotherapy method in CRT.

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Background: Various factors contribute to the development of infection-related acute encephalopathy (AE) in children, such as infectious agents and chronic underlying disorders. We studied underlying disorders in children with AE to identify predisposing factors of AE.

Methods: We investigated underlying disorders or past histories in patients with two types of AE from the database in the Tokai area of Japan between 2009 and 2022: 204 patients with AE with reduced subcortical diffusion (AED) and 137 with clinically mild encephalopathy with a reversible splenial lesion (MERS).

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In Japan, systemic chemotherapy is the standard treatment for unresectable, advanced, or recurrent gastric cancer. However, numerous patients with gastric cancer do not receive late-line treatment because of the rapid progression of gastric cancer. Additionally, late-line treatments, such as nivolumab, trifluridine tipiracil (FTD/TPI), or irinotecan, have limited effects on improving clinical symptoms and delaying the onset of symptoms associated with cancer progression.

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  • A study evaluated the effect of levodopa on gait disturbances in individuals with Dravet syndrome (DS), using a three-dimensional gait analysis (3DGA) in a crossover design with nine participants aged 6-20 years.
  • The results showed significant improvements in gait metrics, including a 4.2-point increase in the Gait Deviation Index (GDI), a 52-meter improvement in the 6-minute walking distance, and enhanced balance.
  • The findings suggest that levodopa may effectively improve gait disturbances in younger individuals with better initial gait performance, with no serious side effects noted, except for one case of fever.
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Objective: To evaluate the impact of daily fraction doses on late genitourinary (GU) toxicity after salvage radiotherapy (SRT) for prostate cancer.

Methods: This multi-institutional retrospective study included 212 patients who underwent SRT between 2008 and 2018. All patients received image-guided intensity-modulated SRT at a median dose of 67.

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