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Thyrotoxic Periodic Paralysis: A Concise Review of the Literature.

Curr Rheumatol Rev

February 2017

Aultman Hospital, Canton, Ohio-44710.2Cleveland Clinic, Cleveland, Ohio-44915, USA.

Background: Thyrotoxic periodic paralysis (TPP) is a rare disease entity highlighted by hypokalemia, flaccid paralysis, and thyrotoxicosis. It usually presents as sudden profound muscle weakness manifested as almost complete immobility and can affect proximal and distal limb muscles, respiratory musculature as well as the cardiac conduction system.

Methods: A comprehensive review of Thyrotoxic periodic paralysis from 1885 to date was carried out by an extensive and thorough literature research including but not limited to Pubmed, Medline and EMBASE.

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