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J Minim Invasive Gynecol
February 2021
Departments of Gynecologic Oncology (Drs. Martino and Thomas and Ms. Johnson, Ms. Wejkszner, and Ms. Makarova); Plastic Surgery (Dr. Jacobs); Obstetrics and Gynecology (Dr. Lazaro), Lehigh Valley Health Network, Allentown, Pennsylvania; Department of Gynecologic Oncology, Ohio State University (Drs. Bixel and Fowler), Columbus, Ohio.
The Laparoscopic Approach to Cervical Cancer (LACC) trial changed the surgical management of cervical cancer worldwide. It was a multinational phase III clinical trial that reported lower survival and higher rate of abdominopelvic recurrences in minimally invasive surgery (MIS) than those of open surgery after hysterectomy. It is possible that tumor exposure to the peritoneal cavity in the MIS arm may account for these differences.
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