The role of TNF-alpha in amygdala kindled rats.

In the present study, the interaction between epileptogenesis and the immune system were studied in a kindling model. First, the effects of a single administration of TNF-alpha (5.0 microg/kg, i.

Thiol-selective mechanism of HIV antigen conjugation with serum IgM, IgG, and IgA.

The effects of HIV antigen glycoproteins gp160, gp41, and gp36 on thiol-dependent specific (affinity) binding of serum IgM, IgG, and IgA with the corresponding antigens were determined by the formation of signal thiol-containing analytes (free nonprotein SH groups). Free nonprotein SH groups were not found in the reaction mixture, which indicated that HIV antigen glycoproteins blocked this process. The results suggest that the thiol-selective mechanism underlies in vitro conjugation of HIV antigen glycoproteins gp160, gp41, and gp36 with serum immunoglobulins.

[Diagnosis of remote metastases of rectal cancer with the aid of minimally invasive diagnostic procedures under computerized tomography control].

At 124 patients who have rectum cancer made computer tomography of a abdominal cavity, retroperitoneal space and small pelvis with the purpose of definition of prevalence of a tumour. Was used computer tomograph "Somatom CRX", "Siemens". Remote metastasis are revealed at 26 patients, their most often localization--liver (45.

[Urea-forming function of the liver in aging rats].

The investigations of some metabolites and enzymes of ornithine cycle were performed for infant and adult rats. The decreasing of enzyme activity and the decreasing of urea production have been shown as a reflection of anabolic processes prevalence for a growing organism.

[Change in urea-forming function of rat liver in the acute and recovery period after radiation exposure].

The results of investigations of some metabolites and enzymes of ornithine cycle in total gamma-irradiated rats are presented. It is shown that ionizing radiation furthers the intensification of liver ammonium binding function. It took place without visible enzyme activation during the first period of defeat.