Integrating sexual and reproductive health in higher education and healthcare services in Ukraine: A sustainable initiative for empowering war-affected youth.

Integrating Sexual Reproductive Health and Rights (SRHR) into educational programs and healthcare services supports the EU Eastern Partnership and the UN's Agenda 2030. A Swedish Institute (SI)-funded project empowers undergraduate students in medicine, psychology, and social work to support SRHR among youth and young adults in wartime and post-war Ukraine by incorporating the subject into university curricula. In August 2024, a study tour to Sweden was conducted by managers and faculty from Ukrainian universities, during which the visitors to Sweden identified the need to establish Youth Clinics at Ukrainian universities to address the SRHR needs of the war-affected youth population.

Kallikrein-kinin system pathogenetic importance in experimental benign prostatic hyperplasia.

Objective: Aim: To analyze the mechanisms of regulation of the body's proteolytic systems during inflammation, detection of inflammation markers in blood and prostate secretions in the experimental benign prostatic hyperplasia in rats.

Patients And Methods: Materials and Methods: The study was conducted on 30 male rats on the model of benign prostatic hyperplasia. Rats were randomized as following: the 1st group (n=6) - intact animals; the 2nd group (n=24) - rats with benign prostatic hyperplasia.

Complications in gynecological surgeries in Ukraine: results a multicenter study.

Objective: . Aim: To analyze the complications during gynecologic surgery procedures and identify possible risk factors associated with this type of surgery in Ukraine.

Patients And Methods: Materials and Methods: We conducted a multicenter, retrospective cohort study in tertiary care hospitals from 12 regions of Ukraine from January, 2021, to December, 2023.

Epidemiology of complications associated with gynecological laparoscopy procedures in Ukraine: results a multicenter study.

Objective: Aim: To estimate the frequency of complications during laparoscopic gynecologic surgery for benign diseases in women and identify associated risk factors in Ukraine.

Patients And Methods: Materials and Methods: A multicenter, prospective cohort study was performed in gynecological departments from 10 regional hospitals of Ukraine between January 1, 2020, to December 31, 2022. The study included gynecologic laparoscopies for benign diseases in women performed at these hospitals.

The study of the hypoxia markers against the background of prolonged hyperglycemia in experimental animals.

Objective: Aim: The aim of article is to investigate the energetic functions of retinal mitochondria under conditions of chronic hyperglycemia to understand the pathogenic mechanisms involved in the development of this diabetic complication.

Patients And Methods: Materials and Methods: The experimental study was carried out on non-linear rats which were divided into 2 groups: intact animals and rats with diabetic retinopathy. We investigated the level of lactate, pyruvate and adenine nucleotides.

Thyroid dysfunction in women with a menopausal syndrome.

Introduction: The thyroid gland has a significant impact on the morphofunctional state of the organs of the female reproductive system, the regulation of the ovarian-menstrual cycle, as well as the age-related decline of the generative and endocrine function of the ovaries.

Material And Methods: The study involved 102 women aged 49-62 years, who were divided into 2 groups. Group I included 54 patients who suffered from manifestations of the menopausal syndrome, and the control group comprised 48 patients whose menopausal period proceeded physiologically.

Histological and immunohistochemical features of the placenta associated with COVID-19: a systematic review and meta-analysis.

Objective: Aim: To make a systematic review and meta-analysis of published data on the study of histological and immunohistochemical features of the placenta in women who had acute coronavirus infection associated with SARS-CoV-2 ("Covid" placentas) during pregnancy.

Patients And Methods: Materials and Methods: The search for literature data is based on the PRISMA methodology); the MEDLINE database (PubMed®) was searched using Medical Subject Headings terms from January 2020 to July 2023. The project was registered in the Open Sience Frame (Project Identifier: DOI 10.

Pregnancy outcomes after assisted reproductive technology among women with endometriosis in Ukraine: results a multicenter study.

Objective: Aim: To evaluate the association between adverse pregnancy outcome, assisted reproductive technology (ART) and a previous diagnosis of endometriosis in Ukraine.

Patients And Methods: Materials and Methods: We conducted a multicentre retrospective cohort study was based on infertility surveillance data among women reproductive age from January 1st, 2017 to December 31st, 2021 in Ukraine. The patients from 10 Ukrainian regions who achieved singleton pregnancy by ART were included in this study.

Factors associated with female infertility in Ukraine: results a multicenter study.

Objective: Aim: To determine the current prevalence of female infertility and characterize and identify risk factors associated with infertility in Ukraine.

Patients And Methods: Materials and Methods: Multicenter prospective cohort study was conducted from January 2021 to December 2023 in twelve medical centers from nine regions of Ukraine. Definitions of infertility were adapted from the World Health Organization.

Designing the future of prenatal care: an algorithm for a telemedicine-enhanced team-based care model.

This study provides a conceptual exploration of an innovative telemedicine-enhanced team-based care (TETC) model, tailored to prenatal care, integrating a multidisciplinary team approach with advanced telemedicine technologies. The algorithm developed for TETC aims to optimize communication and coordination among healthcare professionals, including obstetricians, midwives, nutritionists, and mental health experts. This cohesive team structure ensures a comprehensive care plan encompassing all facets of maternal and fetal health.

Necrotizing enterocolitis in premature infants at different gestation ages.

Objective: Aim: To compare X-ray signs in different gestational and body weight groups of patients with NEC.

Patients And Methods: Materials and Methods: We conducted a retrospective study, enrolling 52 preterm newborns with symptoms of NEC regardless of onset time, who underwent treatment at Neonatal Intensive Care Units in Municipal Non-commercial enterprise "City Children Hospital №2", Odesa. The patients were split into 3 clinical groups: very preterm newborns (VPN), moderately preterm newborns (MPN), and moderately preterm newborns with intrauterine growth restriction (MPN+IUGR).

Postpartum infections and antimicrobial resistance of responsible pathogens in Ukraine: results a multicenter study (2020-2022).

Objective: Aim: To determine the current prevalence of postpartum infections and antimicrobial resistance and antimicrobial resistance of responsible pathogens in Ukraine.

Patients And Methods: Materials and Methods: Multicenter prospective cohort study was conducted from January 2020 to December 2022 in fifteen hospitals from twelve regions of Ukraine. Definitions of healthcare- associated postpartum infection were adapted from the Centers for Disease Control and Prevention's National Healthcare Safety Network.

Endometritis after hysteroscopic procedures in Ukraine: results a multicenter study.

Objective: Aim: To determine the current prevalence of endometritis after hysteroscopic procedures and antimicrobial resistance of responsible pathogens in Ukraine.

Patients And Methods: Materials and Methods: Multicenter prospective cohort study was conducted from January 2020 to December 2022 in fifteen hospitals from twelve regions of Ukraine. Definitions of endometritis were adapted from the Centers for Disease Control and Prevention's National Healthcare Safety Network.

Acceptability of hepatitis C screening and treatment during pregnancy in pregnant women in Egypt, Pakistan, and Ukraine: A cross-sectional survey.

Chronic hepatitis C (HCV) in women of childbearing age is a major public health concern with ∼15 million women aged 15-49 years living with HCV globally in 2019. Evidence suggests HCV in pregnancy is associated with adverse pregnancy and infant outcomes. This includes ∼6% risk of infants acquiring HCV vertically, and this is the leading cause of HCV in children globally.

Building an Efficient Peritoneal Surface Malignancies Program Despite the Lower-Middle-Income Barriers: Ukraine Experience.

Purpose: Cytoreductive surgery/hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) programs are often limited to centers in developed countries because of extensive requirements. We aimed to analyze efficacy and challenges of CRS/HIPEC centers in lower-middle-income settings in the Ukraine example.

Methods: A multicenter descriptive study was conducted using data sets (2008-2022) from Kyiv, Lviv, and Odesa centers.

VULVOVAGINAL CANDIDIASIS AFTER GYNECOLOGICAL SURGERIES AND ADVERSE PREGNANCY OUTCOME IN UKRAINE: A MULTICENTRE STUDY.

Objective: The aim: To investigate the epidemiology and microbiology of vulvovaginal candidiasis (VVC) after gynecological surgeries, and adverse pregnancy outcomes in Ukraine.

Patients And Methods: Materials and methods: Multicenter prospective cohort study was conducted from January 2020 to December 2022 and recruited pregnant and non-pregnant women aged 15-65 years who had sought medical help for vaginal dysbiosis the seven medical clinic from five regions of Ukraine.

Results: Results: Between 2020 and 2022, 2,341 women were followed in gynecological practices, and 1,056 (41.

The Effect of Immunoglobulin G on the Humoral Immunity in Patients with Tuberculosis/HIV Coinfection.

Previously, an increase in clinical effectiveness of the antituberculosis treatment (ATT) and antiretroviral therapy (ART) in case of additional immunoglobulin G (IgG) administration in patients with multidrug-resistant tuberculosis (MDR-TB)/HIV coinfection was reported. The aim of this study was to investigate the impact of IgG administration in addition to the standard second-line ATT and ART on the humoral immunity status in patients with MDR-TB/HIV coinfection immune deficiency. The study involved 52 patients living with HIV with MDR-TB coinfection and CD4+ lymphocyte cell count below 50 cells/μCL.

EXPERIMENTAL BACKGROUND FOR HORMONE-VITAMIN COMPLEX USING IN COURSE OF REHABILITATION AFTER IONIZING RADIATION.

Objective: The aim: To determine the efficacy of the original hormone-vitamin complex in terms of biochemical activity enhancement and muscle system functional activity restoration in the irradiated rat's descendents.

Patients And Methods: Materials and methods: The activity of NADP-dependent malatedehydrogenase and the content of ATP, ADP and AMP were determined in the blood, myocardium and thigh muscles of rats exposed to ionizing gamma-radiation. The rats were also checked in the forced swimming test.