7 results match your criteria: "Ochsner Medical Center for Children[Affiliation]"

Article Synopsis
  • Bloodstream infections (BSIs) are common and serious for kids with acute myeloid leukemia (AML), often linked to central venous access devices (CVADs) used during treatment.
  • This study analyzed the risk of bacterial BSIs in pediatric AML patients based on different types of CVADs (tunneled externalized catheter, peripherally inserted central catheter, and totally implanted catheter) using data from over 500 patients.
  • Results showed no significant difference in BSI rates among the CVAD types during neutropenia, suggesting that the risk factors for BSIs may be specific to patients with AML rather than the type of CVAD used.
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Congenital vertebral synostosis (CVS) is a rare developmental condition due to failure of vertebral segmentation. Vertebrae and their intervertebral discs differentiate and resegment at the time of organogenesis during fetal life. Failure of this embryological process can result in the limitation of mobility of the involved segment.

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Importance: Pediatric acute myeloid leukemia (AML) requires multiple courses of intensive chemotherapy that result in neutropenia, with significant risk for infectious complications. Supportive care guidelines recommend hospitalization until neutrophil recovery. However, there are little data to support inpatient over outpatient management.

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Circadian Variation of Ventricular Arrhythmias in Catecholaminergic Polymorphic Ventricular Tachycardia.

JACC Clin Electrophysiol

November 2017

Department of Cardiology, Children's Hospital Boston, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.

Objectives: The aim of this paper was to investigate whether ventricular arrhythmias in children with catecholaminergic polymorphic ventricular tachycardia (CPVT) show circadian patterns.

Background: Circadian arrhythmic patterns have been established in long QT, Brugada, and early repolarization, but have not been investigated in CPVT.

Methods: This is a multicenter, retrospective review of pediatric CPVT patients, age <21 years at diagnosis.

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We present a case of congenital complete atrioventricular block in a preterm microcephalic male with multiple additional congenital anomalies, including spinal and rib abnormalities. The heart was structurally normal, and maternal tests for autoimmune disorders were negative. The brain had an immature lissencephalic appearance, suggestive of an insult early in gestation.

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