5 results match your criteria: "Ochsner Community Clinical Oncology Program[Affiliation]"

Background: Two arms with FOLFIRI, with or without cetuximab, were initially included in the randomized phase III intergroup clinical trial NCCTG (North Central Cancer Treatment Group) N0147. When other contemporary trials demonstrated no benefit to using irinotecan as adjuvant therapy, the FOLFIRI-containing arms were discontinued. We report the clinical outcomes for patients randomized to FOLFIRI with or without cetuximab.

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Article Synopsis
  • - The study focused on patients with liver-only metastases from colorectal cancer, aiming to evaluate the effects of hepatic artery infusion (HAI) combined with systemic therapy after surgical resection.
  • - Results showed that of 49 patients, median disease-free survival was 1.2 years, with some patients surviving over 5.5 years, despite many having aggressive disease characteristics.
  • - Although the HAI approach indicated potential improvement in survival outcomes compared to past treatments, the overall effectiveness does not justify its continued use due to the development of better systemic chemotherapy options.
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Prevention of breast cancer in high-risk women.

J La State Med Soc

April 1999

Ochsner Community Clinical Oncology Program, Ochsner Clinic, New Orleans, Louisiana, USA.

The results of the National Surgical Adjuvant Breast and Bowel Project (NSABP) Breast Cancer Prevention Trial (BCPT) were released in April 1998. In that trial, 13,388 women who were at high risk of developing breast cancer were randomized to receive tamoxifen or placebo for 5 years. There was a 49% (P < .

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The Ochsner Medical Institutions of New Orleans and Baton Rouge, the Louisiana State Medical Centers in New Orleans and Shreveport, and the Tulane Medical Center of New Orleans are all actively involved in the conduct of National Cancer Institute approved and sponsored clinical trials. Through the efforts of investigators at these institutions, avant-garde, state-of-the-art cancer clinical trials are being made available to the citizens of the state of Louisiana.

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