91 results match your criteria: "Ochsner Clinical School-University of Queensland School of Medicine[Affiliation]"

Nonpharmacologic management of hypertension: a multidisciplinary approach.

Curr Opin Cardiol

July 2017

aDepartment of Physical Therapy and the Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, Illinois, USA bClinic for Cardiology, University Clinical Center Serbia, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia cDivision of Pulmonary, Department of Medicine, Critical Care, Sleep and Allergy, University of Illinois at Chicago, Chicago, Illinois, USA dDepartment of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School-University of Queensland School of Medicine, New Orleans, Louisiana, USA.

Purpose Of Review: Nonpharmacologic lifestyle modification interventions (LMIs), such as increasing physical activity, dietary modification, weight-loss, reducing alcohol consumption and smoking cessation, are effective strategies to lower resting blood pressures (BPs) in prehypertensive or hypertensive patients. However, the limited time shared between a physician and a patient is not adequate to instill an adoption of LMI. The purpose of this review is to therefore highlight evidence-based BP lowering, LMI strategies that can feasibly be implemented in clinical practices.

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Hypertension management in the digital era.

Curr Opin Cardiol

July 2017

aDepartment of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School - University of Queensland School of Medicine, Brisbane, Queensland, Australia bCenter for Healthcare Innovation, Ochsner Health System, New Orleans, Louisiana, USA.

Purpose Of Review: Hypertension (HTN) is the most common chronic disease in the United States, and the standard model of office-based care delivery continues to yield suboptimal outcomes, with approximately 50% of affected patients not achieving blood pressure (BP) control. Poor population-level BP control has been primarily attributed to therapeutic inertia and low patient engagement resulting in significant and preventable morbidity and mortality. This review will highlight the rationale for a reengineered model of care delivery for populations with HTN.

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Article Synopsis
  • Radiotherapy (RT) for breast cancer, especially on the left side, is linked to increased late cardiovascular (CV) complications and mortality.
  • A study analyzing data from over 289,000 patients found that women who underwent left-sided RT had a higher risk of CV death compared to those who received right-sided RT.
  • This difference in risk became more pronounced after 15 years of follow-up, indicating a significant long-term impact of left-sided RT on cardiovascular health.
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The Role of Technology in Healthy Living Medicine.

Prog Cardiovasc Dis

June 2017

Department of Physical Therapy, University of Illinois at Chicago, Chicago, IL; Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL.

Health care consumers are taking control of their health information and desire a greater role in managing their health. Approximately 77% of Americans now own a smartphone and the use of health apps have doubled over the past two years. These effects are particularly notable in patients with chronic disease, now representing half the adult population and responsible for 86% of United States health care (HC) costs and 70% of deaths.

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Personalized Activity Intelligence (PAI) for Prevention of Cardiovascular Disease and Promotion of Physical Activity.

Am J Med

March 2017

K.G. Jebsen Center of Exercise in Medicine at the Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Faculty of Medicine, Trondheim, Norway; School of Human Movement & Nutrition Sciences, University of Queensland, St. Lucia, QLD, Australia.

Purpose: To derive and validate a single metric of activity tracking that associates with lower risk of cardiovascular disease mortality.

Methods: We derived an algorithm, Personalized Activity Intelligence (PAI), using the HUNT Fitness Study (n = 4631), and validated it in the general HUNT population (n = 39,298) aged 20-74 years. The PAI was divided into three sex-specific groups (≤50, 51-99, and ≥100), and the inactive group (0 PAI) was used as the referent.

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The Many Faces of Sudden Death.

Mayo Clin Proc

October 2016

Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School-University of Queensland School of Medicine, New Orleans, LA.

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Body habitus in heart failure: understanding the mechanisms and clinical significance of the obesity paradox.

Future Cardiol

November 2016

Department of Cardiovascular Diseases, John Ochsner Heart & Vascular Institute, Ochsner Clinical School-University of Queensland School of Medicine, 1514 Jefferson Highway, New Orleans, LA 70121, USA.

The prevalence of obesity among adults and children worldwide has reached epic proportions and has become a major independent risk factor for the development of heart failure (HF), in addition to a contributor of hypertension and cardiovascular disease. The implications of obesity in the development of HF involve adverse effects on cardiac structure and function. Despite all of this, in the setting of chronic HF, excess body mass is associated with improved clinical outcomes, demonstrating the presence of an obesity paradox.

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New Concepts in Hypertension Management: A Population-Based Perspective.

Prog Cardiovasc Dis

May 2017

Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School - University of Queensland School of Medicine, and the Center for Healthcare Innovation, Ochsner Health System, New Orleans, Louisiana.

Hypertension (HTN) is the most common chronic disease in the U.S., and the standard model of office-based care delivery has yielded suboptimal outcomes, with approximately 50% of affected patients not achieving blood pressure (BP) control.

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Hypertension is present in 30% of the adult US population and is a major contributor to cardiovascular disease. The established office-based approach yields only 50% blood pressure control rates and low levels of patient engagement. Available home technology now provides accurate, reliable data that can be transmitted directly to the electronic medical record.

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Routine ECG Screening of Young Athletes: Can This Strategy Ever Be Cost Effective?

J Am Coll Cardiol

August 2016

Department of Family Medicine and Department of Orthopedics & Sports Medicine, University of Washington, Seattle, Washington.

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Article Synopsis
  • Transthyretin amyloidosis (ATTR) is a complex disorder affecting multiple organs, with both genetic and non-genetic causes; this study aimed to describe its characteristics in the U.S. using data from the THAOS registry.
  • Analysis revealed that U.S. patients are generally older (average age of 70) and predominantly male (85.4%), with a notable incidence of the Val122Ile mutation and a greater prevalence of wild-type disease compared to patients in other regions.
  • Patients with the Val122Ile mutation showed a higher burden of neurological symptoms and worse quality of life, while survival analysis indicated that advancing age and lower mean arterial pressure are key factors linked to increased mortality, rather than specific
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Coenzyme Q10 and Utility in Heart Failure: Just Another Supplement?

Curr Heart Fail Rep

August 2016

Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School-University of Queensland School of Medicine, New Orleans, LA, USA.

Heart failure affects 5.1 million people in the USA annually. It accounts for a frequent cause of hospitalizations and disability.

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Background: Low cardiorespiratory fitness has been established as a risk factor for cardiovascular-related morbidity. However, research about the impact of fitness on lipid abnormalities, including atherogenic dyslipidemia, has produced mixed results. The purpose of this investigation is to examine the influence of baseline fitness and changes in fitness on the development of atherogenic dyslipidemia.

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The prevalence and severity of obesity have increased in the United States and most of the Westernized World over recent decades, reaching worldwide epidemics. Since obesity worsens most of the cardiovascular disease (CVD) risk factors, not surprisingly, most CVDs, including hypertension, coronary heart disease, heart failure, and atrial fibrillation, are all increased in the setting of obesity. However, many studies and meta-analyses have demonstrated an obesity paradox with regards to prognosis in CVD patients, with often the overweight and mildly obese having a better prognosis than do their leaner counterparts with the same CVD.

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The Role of Technology in Chronic Disease Care.

Prog Cardiovasc Dis

April 2017

Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School - University of Queensland School of Medicine, New Orleans, LA.

Chronic disease represents the epidemic of our time, present in half the adult population and responsible for 86% of United States (US) healthcare costs and 70% of deaths. The major chronic diseases are primarily due to health risk behaviors that are widely communicable across populations. As a nation, the US has performed poorly in managing chronic disease, in large part because of a failed delivery model of care.

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Special Editor's Page--Two Years as Editor-in-Chief.

Prog Cardiovasc Dis

July 2016

Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School-University of Queensland School of Medicine, New Orleans, LA. Electronic address:

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Update on Obesity and Obesity Paradox in Heart Failure.

Prog Cardiovasc Dis

July 2016

Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School-University of Queensland School of Medicine, New Orleans, LA.

Obesity has reached epidemic proportions in most of the Westernized world. Overweightness and obesity adversely impact cardiac structure and function, including on both the right and, especially, left sides of the heart, with adverse affects on systolic and, especially, diastolic ventricular function. Therefore, it is not surprising that obesity markedly increases the prevalence of heart failure (HF).

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The role of cardiorespiratory fitness on plasma lipid levels.

Expert Rev Cardiovasc Ther

November 2015

c 3 Department of Exercise Science, Arnold School of Public Health, University of South Carolina, 921 Assembly Street, Columbia, SC 29208, USA.

Dyslipidemia is a treatable risk factor for cardiovascular disease. Epidemiological studies have demonstrated the importance of treatment for abnormalities in total cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides. Aside from pharmacotherapy, exercise and cardio-respiratory fitness have been shown to have beneficial effects on decreasing cardiovascular disease risk.

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Association of Cardiorespiratory Fitness With Coronary Heart Disease in Asymptomatic Men.

Mayo Clin Proc

October 2015

Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia; Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia.

Objective: To examine the association of cardiorespiratory fitness (CRF) with risk of coronary heart disease (CHD) while controlling for an individual's Framingham Risk Score (FRS)-predicted CHD risk.

Patients And Methods: The study included 29,854 men from the Aerobics Center Longitudinal Study, who received a baseline examination from January 1, 1979, to December 31, 2002. Coronary heart disease events included self-reported myocardial infarction or revascularization or CHD death.

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Exercise and the cardiovascular system: clinical science and cardiovascular outcomes.

Circ Res

July 2015

From the Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School-University of Queensland School of Medicine, New Orleans, LA (C.J.L., R.V.M.); Department of Physical Therapy and Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago (R.A.); Department of Kinesiology, East Carolina University, Greenville, NC (D.L.S.); Department of Preventive Medicine, Pennington Biomedical Research Center, Baton Rouge, LA (N.M.J., T.S.C.); School of Kinesiology, Louisiana State University, Baton Rouge (N.M.J.); Department of Exercise Science, Arnold School of Public Health University of South Carolina, Columbia (X.S., S.N.B.); Department of Kinesiology, College of Human Sciences, Iowa State University, Ames (D.c.L.); Department of Health and Kinesiology, Texas A&M University, College Station (C.P.E.); and Department of Cardiovascular Disease, Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City (J.H.O.).

Substantial evidence has established the value of high levels of physical activity, exercise training (ET), and overall cardiorespiratory fitness in the prevention and treatment of cardiovascular diseases. This article reviews some basics of exercise physiology and the acute and chronic responses of ET, as well as the effect of physical activity and cardiorespiratory fitness on cardiovascular diseases. This review also surveys data from epidemiological and ET studies in the primary and secondary prevention of cardiovascular diseases, particularly coronary heart disease and heart failure.

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Heart failure and diabetes mellitus contribute significantly to the morbidity and mortality of the US population. The combined economic impact on the US health care system reaches nearly $300 billion. Much of this cost stems from the frequent hospital admissions and direct cost of managing the two diseases.

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