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Correlation of alanine aminotransferase levels and a histological diagnosis of steatohepatitis with ultrasound-diagnosed metabolic-associated fatty liver disease in patients from a centre in Nigeria.
BMC Gastroenterol
May 2024
Department of Medicine, Faculty of Clinical Sciences, Obafemi Awolowo University and Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Osun State, Nigeria.
Background: Metabolic-associated fatty liver disease (MAFLD) is defined as the occurrence of hepatic fat accumulation in patients with negligible alcohol consumption or any other cause of hepatic steatosis. This study aimed to correlate the ultrasound-based diagnosis of MAFLD with the histological diagnosis of nonalcoholic steatohepatitis (NASH) and alanine aminotransferase (ALT) levels in patients with MAFLD.
Methods: This was a hospital-based cross-sectional study of 71 patients with MAFLD diagnosed by ultrasound.