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Obafemi Awolowo University Teaching Hos... Publications | LitMetric

776 results match your criteria: "Obafemi Awolowo University Teaching Hospitals' Complex[Affiliation]"

Objective: To evaluate the worldwide use of FIGO's two systems for the classification of causes and contributors to nongestational abnormal uterine bleeding in the reproductive years by obstetrics and gynecology professionals worldwide, to identify knowledge gaps, and explore barriers to implementation.

Methods: An electronic survey was developed by members of FIGO's Menstrual Disorders and Related Health Impacts (MDRHI) Committee to assess knowledge of abnormal uterine bleeding (AUB) and the two FIGO AUB systems among obstetricians and gynecologists. The survey was conducted online from February 28 to June 30, 2023, and comprised demographic questions, educational content inquiries, and a knowledge assessment.

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The incidence of cesarean section is dramatically increasing worldwide, whereas the training opportunities for obstetrician/gynecologists to manage complex cesarean section appear to be decreasing. This may be attributed to changing working hours directives and the increasing use of laparoscopy for gynecological surgical procedures, including in gynecological oncology. Various situations can create surgical difficulties during a cesarean section; however, two of the most frequent are complications from previous cesarean (myometrial defects, with or without placental intrusion and peritoneal adhesions) and the high risk of postpartum hemorrhage (uterine overdistension, abnormal placentation, uterine fibroids).

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Background/objective: Rheumatic diseases (RMDs) are among the leading health burdens and causes of disability globally. Interestingly, they are on the rise due to the increasingly ageing population. Inflammatory RMDs are not left behind in the rise, especially in Africa, where they were thought to be rare as there has been increasing reportage of these diseases in recent years.

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Cerebral venous sinus thrombosis (CVST) is an uncommon and underreported neurological condition. This condition has varied aetiologies, clinical manifestations, and significant sequelae if left untreated. We report the case of a 10-year-old male with fever, altered sensorium, cranial nerve neuropathies, and left hemiplegia.

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This study assessed the factors militating against the effective implementation of electronic health records (EHR) in Nigeria, the computerization of patients' health records with a lot of benefits including improved patients' satisfaction, improved care processes, reduction of patients' waiting time, and medication errors. Despite these benefits, healthcare organizations are slow to adopt the EHR system. Therefore, the study assessed the factors militating against the effective implementation of the EHR system, the level of awareness of EHR, and the utilization of electronic health records; it also investigated the factors militating against the effective implementation of EHR.

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This study is aimed at determining the prevalence of oral HPV infection and the risk indicators for oral HPV carriage in people living with HIV. Data on socio-demographics, sexual behavioral practices, and lifestyle practices of the participants were collected from 66 people living with HIV. The HIV parameters of each study participant were obtained from clinical records.

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Article Synopsis
  • Spirometry is a test used to evaluate lung function by comparing it to normal levels in healthy non-smokers, focusing on metrics like forced vital capacity (FVC) and the FEV/FVC ratio.
  • The study analyzed data from over 14,000 participants aged 40 and older across 41 sites, revealing regional differences in FVC tied to factors like age and height, categorized into four regions: Europe/richer countries, Near East, Africa, and Far East.
  • Findings showed significant regional variations in FVC values between men and women, particularly in Europe compared to the Far East, but minimal differences in the FEV/FVC ratio across regions.
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Background: p53 is a tumor suppressor gene. p53 expression in epithelial ovarian tumors (EOTs) is correlated with their biological behavior and predicts patient overall survival. However, there is a dearth of knowledge regarding p53 expression in these tumors among women from southwest Nigeria.

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Article Synopsis
  • - The study surveyed 199 resident doctors in Osun State, Nigeria, to evaluate their knowledge, attitudes, and involvement in research, revealing a disparity between their understanding of research and actual participation.
  • - Results showed that while 60.8% had good research knowledge, only 29.2% had a positive attitude, and a mere 11.6% felt confident in conducting research independently.
  • - The findings suggest that most residents lack sufficient involvement in research due to unmet needs for mentorship and guidance, indicating a need for initiatives to enhance practical research engagement.
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Background: Hemorrhoidectomy is considered as the most effective approach for patients with grade III and grade IV hemorrhoids; the operative procedure may be associated with significant postoperative pain and other complications. Several surgical techniques and devices have been developed to overcome these postoperative problems.

Objective: To compare perioperative and postoperative outcomes of hemorrhoidectomy performed with the LigaSure and the conventional Milligan-Morgan hemorrhoidectomy among Nigerian patients with symptomatic hemorrhoids.

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Article Synopsis
  • In Nigeria, gastric cancer ranks as the 10th most common and 9th most deadly cancer, but there is limited data available to fully understand it.
  • A study evaluated 138 patients diagnosed with gastric cancer over 15 years, finding that most patients presented with significant weight loss and anorexia, and many had advanced disease.
  • Most patients received some form of treatment, with nearly half undergoing both chemotherapy and surgery, though over 50% were deceased by the time of follow-up, highlighting the need for improved data quality and timely interventions.
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Introduction: Thrombospondin-1 (TSP-1) is a key protein product of activated platelets which is significantly increased in sickle cell vaso-occlusive crisis (VOC) and other inflammatory conditions. This study aims to determine TSP-1 levels and their relationship with platelet indices and inflammation.

Objective: To evaluate TSP-1 levels in sickle cell anaemia (SCA) patients and assess their relationship with platelet indices and inflammation.

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Background: Although Helicobacter pylori infection (H. pylori) prevalence in Africa has declined in the last decade, it remains concerningly high. H.

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Article Synopsis
  • Adult-onset aqueductal stenosis (AOAS) is a rare cause of hydrocephalus in adults, and its understanding, especially in Africa, is limited—this study focused on its presentation and outcomes in Nigeria from 2008 to 2023.* -
  • The research included 8 patients (7 males, 1 female) aged 18 to 50, primarily presenting with headaches and visual problems, with some experiencing additional symptoms like cognitive deficits and cerebrospinal fluid leaks.* -
  • Ventriculoperitoneal shunt surgery was performed on most patients, leading to favorable outcomes, highlighting the importance of diagnosing AOAS early to prevent severe complications like vision loss.*
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Article Synopsis
  • - The study examines out-of-pocket costs for breast cancer treatment in Nigeria, highlighting that most patients face significant financial burdens, with a majority experiencing catastrophic health expenditures (CHE) due to the high costs of care.
  • - Data was gathered from 71 patients undergoing treatment, revealing that 78.9% to 100% experienced CHE, as their healthcare costs often exceeded 40% of their ability to pay or set income thresholds, and most patients lacked health insurance.
  • - The findings underscore the urgent need for policy changes to improve access to affordable cancer care in Nigeria, given that over 70% of patients at a major facility are financially strained by their treatment.
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Article Synopsis
  • The study examines the impact of the FIGO-WATOG One World Exchange clinical program on the training of postgraduate obstetrics and gynecology (obgyn) trainees in October 2023 in France.
  • Data was collected through a 31-item questionnaire distributed to 51 participants, with a 68.6% response rate, revealing demographics such as age, gender, and training year.
  • The majority of participants found the exchange beneficial, with many noting significant differences in medical practices, and believed it would enhance their clinical skills upon returning home.
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Article Synopsis
  • Cholecystectomy and common bile duct exploration are frequent surgeries in Nigeria that can lead to complications like biliary tree injury and retained stones, necessitating repeat surgeries.
  • A study at Obafemi Awolowo University Teaching Hospital examined the use of endoscopic retrograde cholangiopancreatography (ERCP) for managing these complications from March 2018 to April 2023, using various imaging techniques before the procedures.
  • The study involved 72 ERCPs on 45 patients, with common issues like ascending cholangitis and retained stones, showcasing that ERCP was successful and reduced unnecessary surgeries, with recommendations for swift referrals in such cases.
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Article Synopsis
  • - This case report describes a rare instance of metastatic signet ring carcinoma in the ovary of a 46-year-old Black African woman, occurring alongside a benign fibroma, highlighting the complexity of ovarian lesions.
  • - The patient experienced significant abdominal swelling and was found to have a large mass in the right ovary, along with signs of metastasis in the lungs and liver, as indicated by imaging and elevated tumor markers (CA 125 and CA 19-9).
  • - Surgical intervention involved a total abdominal hysterectomy and bilateral salpingo-oophorectomy, revealing a mix of spindle cells and signet ring cells in the ovarian tissues, illustrating the unique histological findings associated with this case.
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Article Synopsis
  • - Approximately 32 million pregnant women in sub-Saharan Africa are at risk of malaria each year, prompting the WHO to recommend at least three doses of intermittent preventive treatment (IPTp) using sulphadoxine-pyrimethamine (SP) starting in the second trimester.
  • - A cross-sectional study in Osun State, Nigeria, from October 2020 to March 2021 found that only 12.58% of pregnant women received three or more doses of IPTp-SP, with 46.67% adhering to dosage guidelines before sample collection.
  • - The study indicates low utilization and inadequate adherence to IPTp-SP, highlighting the need for increased awareness and possibly implementing directly observed therapy to improve treatment compliance.
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Article Synopsis
  • * Low- and middle-income countries in Africa suffer significant health consequences from WASH-related diseases, with issues like poverty, illiteracy, and climate change hindering effective interventions and leading to millions of deaths annually.
  • * Recommendations for improving WASH practices include implementing strong financial frameworks, providing skills training, and utilizing tools like WASH Fit to enhance infrastructure and address health impacts while also contributing to economic growth and sustainability.
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Article Synopsis
  • * A systematic review and meta-analysis of existing literature found a migraine prevalence of 16% among 7,768 participants in Nigeria, with higher rates in women and various common triggers identified, such as fatigue and emotional stress.
  • * The conclusion stresses the urgent need for improved healthcare policies and treatment strategies, as many individuals experience inadequate pain relief and side effects from common migraine medications.
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The Evolving Role of Palliative Care in Older People with Glioblastoma.

World Neurosurg

December 2024

Department of Global Health and Development, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom; Office for Research, Innovation and Extension Services, Southern Leyte State University, Sogod, Southern Leyte, Philippines; Center for University Research, University of Makati, Makati City, Philippines.

Article Synopsis
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Intersectionality Between Country, Gender and Funding in Authorship for Phase III Trials Presented at the ASCO Annual Meeting 2022.

JCO Glob Oncol

October 2024

Department of Clinical Research, Faculty of Medicine University of Bern and Department of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Article Synopsis
  • The study examines disparities in location, gender, and funding among leadership roles in oncology clinical trials presented at the ASCO22 conference, highlighting the need for policies that promote diversity.
  • Data from 239 phase III abstracts revealed a predominance of high-income country (HIC) institutions, with female representation as lead and senior authors at 29% and 23%, respectively.
  • The findings indicate significant industry sponsorship, with 62% of trials funded by industry, and reflect an ongoing pattern of underrepresentation of women and low-income country authors in the field.
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Article Synopsis
  • A 26-year-old woman experienced obstructive jaundice and significant abdominal swelling due to a large choledochal cyst.
  • Investigations showed that the cyst caused a blockage, leading to high bilirubin levels in her blood.
  • After surgery to remove the cyst and reroute her bile duct, she has been doing well in her follow-ups over the past 6 months.
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