Olive mill wastewater treatment using coagulation/flocculation and filtration processes.

Olive mill wastewater (OMWW), a pollutant resulting from the olive oil industry, poses a serious ecological challenge due to its high pollution load. This effluent is highly concentrated in chemical oxygen demand (COD), which is 200 times higher than that of sewage wastewater. Moreover, OMWW is characterized by a strong acidity, high content of fatty matter, and high concentration of phenolic compounds.

"I'm better than you": assessing the presence of optimistic bias among Italian hunters.

According to the latest scientific evidence, consumers appreciate hunted wild game meat (HWGM), but its consumption may expose them to some risks. Hunters produce HWGM, even if they may find it hard to identify themselves as food producers since in Western countries, hunting is practiced mostly as a leisure activity. Thus, hunters may underestimate the risk associated with HWGM handling, failing to preserve its safety during the production process.

Eccentricity pacing and rapid termination of the early Antarctic ice ages.

Earth's obliquity and eccentricity cycles are strongly imprinted on Earth's climate and widely used to measure geological time. However, the record of these imprints on the oxygen isotope record in deep-sea benthic foraminifera (δO) shows contradictory signals that violate isotopic principles and cause controversy over climate-ice sheet interactions. Here, we present a δO record of high fidelity from International Ocean Drilling Program (IODP) Site U1406 in the northwest Atlantic Ocean.

MODULATION OF GUT MICROBIOTA THROUGH PHYSICAL ACTIVITY IN INDIVIDUALS WITH OBESITY - A SYSTEMATIC REVIEW.

Overweight/obesity (OW/OB) have been associated with gut dysbiosis, changes in gastrointestinal motility and sedentary behavior, contributing to metabolic and inflammatory alterations. This systematic review aims to assess the evidence supporting the influence of physical activity and exercise on gut microbiota composition and diversity in OW/OB and was conducted according to PRISMA guidelines, using Medline, Embase, Ebsco and Scopus databases. Risk of bias was assessed with RoB 2 for randomized controlled trials (RCT), ROBINS-I for non-RCT and JBI Critical Appraisal tool for cross-sectional studies.

Effects of chronic empathic stress on synaptic efficacy, as well as short-term and long-term plasticity at the Schaffer collateral/commissural- CA1 synapses in the dorsal hippocampus of rats.

Empathy, the ability to comprehend and share others' emotional states, impacts brain functions. This in vivo electrophysiological study explored the influence of chronic empathic stress on synaptic efficacy, as well as short-term and long-term plasticity at the Schaffer collateral/Commissural - CA1 synapses in the dorsal hippocampus of rats, in situations of social equality and inequality. Forty-eight male rats were randomized into six groups: control, pseudo-observer, pseudo-demonstrator, observer, demonstrator, and co-demonstrator (Co, Pse-Ob, Pse-De, Ob, De, Co-De) groups.

Utilizing Lactation Acuity to Improve Lactation Services in a U.S. Hospital.

National staffing guidelines for hospital lactation services do not account for the lactation acuity of breastfeeding patients. Higher acuity breastfeeding couplets require a higher level of knowledge and skill from lactation care providers. In these cases, a referral to an International Board Certified Lactation Consultant (IBCLC) is recommended for appropriate management.

Spinodal Decomposition by a Two-Step Procedure for Nano Porous Silica.

The phase separation of the NaO-BO-SiO system was explored both theoretically and experimentally in order to attain a spinodal structure having a narrowed periodic distance (<70 nm) with the porosity being kept at ∼60%. The phase separation was dealt with by two stages: an initial thermodynamic process of spinodal decomposition and a latter growth of the spinodal structure. The initial structural development was related to the interfacial energy and the change in free energy caused by phase separation.

H NMR-Based Metabolomic Signatures in Rodent Models of Sporadic Alzheimer's Disease and Metabolic Disorders.

Alzheimer's disease (AD) is a chronic neurological disorder that impacts the elderly population all over the globe. Evidence suggests association between AD and metabolic disorders such as diabetes mellitus (DM) and obesity (OB). The present study is an attempt to evaluate metabolic alterations in the serum and brain through NMR spectroscopy with the aim to identify shared metabolic signatures.

[Pollution Characteristics and Ecological Risks of Fluorescent Whitening Agents in Surface Water of Hutuo River Basin].

Fluorescent whitening agents （FWAs） are chemical additives that exhibit remarkable whitening effects and have been widely used in the production of detergents, paper, textiles, plastics, and coatings. The production and use of FWAs spans more than 60 years in China； however, the occurrence characteristics of FWAs in environmental water remain unknown. Therefore, a solid phase extraction-ultrahigh performance liquid chromatography-triple quadrupole mass spectrometry （HPLC-MS/MS） method for the trace determination of 11 non-ionic FWAs in surface water was developed.

Food choices, microstructure of ingestive behavior and sensory perceptions after bariatric surgery in women: A cross-sectional study.

Unlabelled: Results regarding the impact of bariatric surgery (BS) on food choices are inconsistent between studies based on self-reported questionnaires, and those using direct measurements. Moreover, the determinants of the modifications of food choices after BS, if any, are still poorly understood. This study compared food choices, food liking, microstructure of ingestive behavior and sensory perceptions between women who had BS in the last 18 months (BS group, n = 19; Roux-en-Y gastric bypass or sleeve gastrectomy) and women with BMI ≥35 kg m (OB group, n = 17) in ecological conditions and explored the associations of food choices with sensory perceptions and food liking.

The Nexus Between Traditional Chinese Medicine and Immunoporosis: Implications in the Treatment and Management of Osteoporosis.

Osteoporosis (OP) is a globally prevalent bone disease characterized by reduced bone mass and heightened fracture risk, posing a significant health and economic challenge to aging societies worldwide. Osteoimmunology-an emerging field of study-investigates the intricate relationship between the skeletal and the immune systems, providing insights into the immune system's impact on bone health and disease progression. Recent research has demonstrated the essential roles played by various immune cells (T cells, B cells, macrophages, dendritic cells, mast cells, granulocytes, and innate lymphoid cells) in regulating bone metabolism, homeostasis, formation, and remodeling through interactions with osteoclasts (OC) and osteoblasts (OB).

Resident Performance on the Obstetrics and Gynecology In-Training Examination After Implementation of a New Academic Curriculum.

Background The goals of the annual Council on Resident Education in Obstetrics and Gynecology In-Training Examination (CREOG-ITE) are to provide residents with an assessment of their knowledge and program directors an assessment of their residency programs. Research has shown that a score greater than 200 is correlated with passing the qualifying board examination. We observed a substantial number of our residents were not performing well on the exam, which prompted the implementation of a new academic program aimed at determining the impact of an academic curriculum addition on CREOG-ITE scores in an American College of Graduate Medical Education (ACGME) accredited obstetrics and gynecology (OB/GYN) residency program.

Obstetrics and Gynecology Provider Experience Screening for Harmful Alcohol Use: An Unmet Need for Standardized Screening and Intervention.

Introduction Early identification of at-risk alcohol use is key to preventing complications of alcohol use disorder (AUD). Obstetrics and gynecology (OB/GYN) providers are in a unique position to screen for alcohol use in young female patients who may not otherwise seek traditional primary care. The purpose of this study was to learn how OB/GYN providers screen for and manage harmful alcohol use in their clinical care.

Fecal deoxycholic acid associates with diet, intestinal microbes, and total bilirubin in primary sclerosing cholangitis.

Background & Aims: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with a strong association with inflammatory bowel disease and variable disease progression. We aimed to gain insights into the role of fecal bile acids (BA) on disease progression by determining the relationships between fecal BA, diet, and gut microbes, with markers of disease progression, BA synthesis, and farnesoid X receptor (FXR) activity.

Methods: BA levels in serum and stool, dietary intake, and markers of BA synthesis, and FXR activity were measured in 26 patients with early stage, large duct PSC.

Faculty retention in academic OB/GYN: comprehensive strategies and future directions.

The retention of academic faculty, particularly in the field of Obstetrics and Gynecology (OB/GYN), has become a growing challenge in the post-COVID era. The healthcare landscape has been dramatically altered, leading to a "Great Exit" where a large number of faculty members are resigning or retiring early. This phenomenon is not just a financial burden as recruitment costs have skyrocketed, but also poses a threat to the stability and reputation of academic institutions.

Role of estradiol level before progesterone start on outcomes of frozen embryo transfer; a systematic review and meta-analysis.

Estradiol (E2) levels on the day progesterone starts may negatively impact implantation, ongoing pregnancy, and live birth rates in frozen embryo transfer (FET). Overall, while the picture isn't entirely clear, some evidence suggests maintaining estradiol levels within a specific range before starting progesterone might be beneficial for frozen transfer success. So we performed a systematic review and meta-analysis to find out the rate of pregnancy-related outcomes of frozen embryo transfer in different level of E2.

DNMT aberration-incurred GPX4 suppression prompts osteoblast ferroptosis and osteoporosis.

Osteoporosis (OP) is a common and fracture-prone skeletal disease characterized by deteriorated trabecular microstructure and pathologically involving various forms of regulated bone cell death. However, the exact role, cellular nature and regulatory mechanisms of ferroptosis in OP are not fully understood. Here, we reported that OP femurs from ovariectomized (Ovx) mice exhibited pronounced iron deposition, ferroptosis, and transcriptional suppression of a key anti-ferroptotic factor GPX4 (glutathione peroxidase 4).

Enhancing Hole Transport and Autonomous Healing Properties of Supramolecular Columns in Unsymmetrical Discotics.

Designing smart autonomous healing soft materials is crucial to attaining cost-efficiency and optimal performance in organic semiconductors. In this context, we design an unsymmetrical thiophene-fused phenazine (TFP)-based discotic liquid crystal (DLC) with the goal of creating an active organic semiconductor that encompasses favorable attributes, such as polarizability, mobility, and processability. Aligned with our objective, we successfully synthesized two unsymmetrical TFP core-based DLCs by linking alkyl chains of variable lengths at the periphery through a coupling reaction.

Native RNA nanopore sequencing reveals antibiotic-induced loss of rRNA modifications in the A- and P-sites.

The biological relevance and dynamics of mRNA modifications have been extensively studied; however, whether rRNA modifications are dynamically regulated, and under which conditions, remains unclear. Here, we systematically characterize bacterial rRNA modifications upon exposure to diverse antibiotics using native RNA nanopore sequencing. To identify significant rRNA modification changes, we develop NanoConsensus, a novel pipeline that is robust across RNA modification types, stoichiometries and coverage, with very low false positive rates, outperforming all individual algorithms tested.