Novel environmental variables help explain winter weather effects on activity and habitat selection of greater sage-grouse along the border of Colorado and Wyoming, USA.

For non-hibernating species within temperate climates, survival during severe winter weather often depends on individuals' behavioral response and available refugia. Identifying refugia habitat that sustains populations during adverse winter conditions can be difficult and complex. This study provides an example of how modeled, biologically relevant snow and weather information can help identify important relationships between habitat selection and dynamic winter landscapes using greater sage-grouse (Centrocercus urophasianus, hereafter "sage-grouse") as a model species.

Estimating the prevalence of diabetic retinopathy in electronic health records with massive missing labels.

Objective: The paper aims to address the problem of massive unlabeled patients in electronic health records (EHR) who potentially have undiagnosed diabetic retinopathy (DR). It is desired to estimate the actual DR prevalence in EHR with 96 % missing labels.

Materials And Methods: The Cerner Health Facts data are used in the study, with 3749 labeled DR patients and 97,876 unlabeled diabetic patients.

Gene model for the ortholog of in .

Gene model for the ortholog of Downstream of raf1 ( ) in the May 2011 (Broad dper_caf1/DperCAF1) Genome Assembly (GenBank Accession: GCA_000005195.1 ) of . This ortholog was characterized as part of a developing dataset to study the evolution of the Insulin/insulin-like growth factor signaling pathway (IIS) across the genus using the Genomics Education Partnership gene annotation protocol for Course-based Undergraduate Research Experiences.

Drift in small populations predicts mate availability and the breakdown of self-incompatibility in a clonal polyploid.

Mate limitation in small populations can reduce reproductive fitness, hinder population growth, and increase extinction risk. Mate limitation is exacerbated in self-incompatible (SI) taxa, where shared S-alleles further restrict mating. Theory suggests genetic drift as a predictor of mate limitation and the breakdown of SI systems.

Emergence and Genetic Characterization of KLUC-3 Extended-Spectrum β-lactamase-producing Escherichia coli ST95 High-Risk Clone Causing Nosocomial Infection in Japan.

Objectives: KLUC β-lactamase is a minor extended-spectrum β-lactamase (ESBL) derived from chromosome-encoded cefotaximase in Kluyvera cryocrescens. This study aimed to characterize the genetic context of KLUC-3-producing Escherichia coli and bla-harboring plasmids and assess nosocomial transmission.

Methods: In a national genomic surveillance conducted in 2019 and 2020, KLUC-3-producing E.

Mutational disparities in colorectal cancers of White Americans, Alabama African Americans, And Oklahoma American Indians.

The high incidence and mortality rates of colorectal cancer (CRC) in Alabama African Americans (AAs) and Oklahoma American Indians (AIs) are recognized as cancer disparities, yet the underlying causes have been poorly demonstrated. By evaluating CRC whole-exome sequencing and mutational profiles, here we report sets of mutated genes whose frequencies differed significantly (p < 0.05) in a race-specific manner.

Long-term impact of atrial fibrillation catheter ablation on heart failure with preserved ejection fraction.

Background: The efficacy of catheter ablation as a treatment approach for patients with concurrent atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) has been inadequately investigated.

Objective: This study's objective was to assess the effectiveness of atrial fibrillation ablation (AFA) in patients with heart failure with preserved ejection fraction.

Methods: Utilizing the TriNetX research network, we identified individuals aged 18 and older with atrial fibrillation (AF) and concurrent heart failure with preserved ejection fraction (HFpEF) from January 1, 2010, to June 1, 2021.

Evaluation of hydrogen storage in sandstone reservoirs using H nuclear magnetic resonance spectroscopy.

Evaluation of the hydrogen storage capacity of porous rocks is crucial for underground hydrogen storage. Using H nuclear magnetic resonance (NMR) spectroscopy, we successfully characterized the hydrogen responses and identified storage mechanisms in Berea sandstone under varying water saturation. The results indicate that the injected hydrogen behaves as a free gas phase and is capable of occupying the empty pore volume regardless of the saturation state.

The Significance of Detecting an Unusual Myeloblast Immunophenotype in a Presumptive Clinical Diagnosis of Myelodysplastic Syndromes.

Context.—: Blasts in myelodysplastic syndromes (MDSs) typically have a primitive myeloid immunophenotype (CD34+CD117+CD13+CD33+HLA-DR+). On rare occasions, blasts were found to be CD34 negative or minimally expressed in a presumptive MDS.

Combination of FSH and testosterone could enhance activation of primordial follicles and growth of activated follicles in 1-day-old mice ovaries cultured for 12 days.

Treatment with follicle-stimulating hormone (FSH) and testosterone (T2) and their combination have been observed to be influential on ovarian follicles of 1-day-old mice ovaries cultured for 8 days. Given that extension of the culture period could positively impact the development of follicles in cultured ovaries, the present study was conducted to evaluate the main and interaction effects of FSH by T2 on the development of ovarian follicles in 1-day-old mice ovaries cultured for 12 days. One-day-old mice ovaries were initially cultured with base medium for 4 days; thereafter, different hormonal treatments were added to the culture media, and the culture was continued for 8 additional days until day 12.

Serious harm reduction protective behavioral strategies reduce consequences associated with alcohol-induced blackouts in college students.

Objective: Alcohol-induced blackouts (AIBs) have been associated with increased alcohol-related consequences. Serious harm reduction (SHR) protective behavioral strategies may reduce consequences when students are drinking heavily. We examined whether SHR weakened the relationship between AIBs and a) total consequences and b) serious consequences (e.

Impact of Dietitian-Delivered Motivational Interviewing Within a Food is Medicine Intervention Targeting Adults Living With and Beyond Cancer.

Food is medicine (FIM) interventions are a strategy for preventing and managing chronic disease via diet. These interventions often combine the provision of food with access to behavior change support (e.g.

Understanding the financial barriers to treatment among individuals with opioid use disorder: a focus group study.

Introduction: Despite the established effectiveness and relatively widespread availability of Medications for Opioid Use Disorder, individuals seeking treatment frequently encounter various structural and social barriers, including costs of treatment. This study aimed to understand the financial barriers that affect treatment continuation in individuals with opioid use disorder (OUD).

Methods: In this qualitative study, seven semi-structured in-depth focus group interviews were conducted among 28 participants in treatment for OUD.

Efficacy of Laser Activated vs Sonic Activated Irrigation for Debris Removal in Conservatively Instrumented Root Canals.

Introduction: To compare the efficacy of laser activated and sonic activated irrigation on the removal of debris in mesial root canal systems of mandibular molars using micro-computed tomographic (micro-CT) analysis.

Methods: Forty-eight mesial roots of extracted mandibular molars with isthmus were selected and randomly allocated into two groups: Sonic Group and Laser Group. The root canals were minimally instrumented to a maximum apical file size of 20/06v (DCTaper, SSWhite, NJ).

The physicochemical properties of lipopolysaccharide chemotypes regulate activation of the contact pathway of blood coagulation.

Lipopolysaccharide (LPS) is the primary pathogenic factor in Gram-negative sepsis. While the presence of LPS in the bloodstream during infection is associated with disseminated intravascular coagulation, the mechanistic link between LPS and blood coagulation activation remains ill-defined. The contact pathway of coagulation-a series of biochemical reactions that initiates blood clotting when plasma factors XII (FXII) and XI (FXI), prekallikrein (PK) and high molecular weight kininogen (HK) interact with anionic surfaces-has been shown to be activated in Gram-negative septic patients.

Countermovement Jumps and Acute to Chronic Workload Ratios in Low, Moderate, and High Jump Load Groups Throughout a Division I Volleyball Season.

Sanders, GJ, Skodinski, S, Cabarkapa, DV, Howard, M, Cabarkapa, D, Kollock, RO, and Peacock, CA. Countermovement jumps and acute to chronic workload ratios in low, moderate, and high jump load groups throughout a Division I volleyball season. J Strength Cond Res XX(X): 000-000, 2024-The purpose of the study was to evaluate the effects of low, moderate, and high jump loads on the acute to chronic workload ratio (ACWR) and neuromuscular fatigue throughout a Division I volleyball season.

Impact of Medical Improvisation on Therapeutic Use of Self: A Randomized Controlled Waitlist Study.

Importance: The application of interpersonal skills is considered therapeutic use of self, a pillar of occupational therapy practice, and a required competency for occupational therapy education (American Occupational Therapy Association [AOTA], 2020). Medical improvisation (medical improv) uses the principles of improvisational theater to enhance professional competencies and shows promising results in health professions education (Gao et al., 2019).

Applying the Quadrant Method for Pumping-Trace Metal Correlations in Variable Time, Low-Data Systems.

Due to increasing global demand for fresh water, it is increasingly necessary to understand how aquifer pumping affects groundwater chemistry. However, comprehensive predictive relationships between pumping and groundwater quality have yet to be developed, as the available data, which are often collected over inconsistent time intervals, are poorly suited for long-term historical correlation studies. For example, we needed an adequate statistical method to better understand relationships between pumping rate and water quality in the City of Norman (OK, USA).

Synergic Cellulose Nanofiber/Tourmaline Nanoparticle-Assembled Layered Piezoelectric Cryogels for High-Performance Airborne Particulate Filtration.

Here, hybrid stimuli-responsive (exhibiting pyroelectricity and piezoelectricity) porous cryogels are engineered by embedding tourmaline nanoparticles (TNs) in a cellulose nanofiber (CNF) skeleton to generate high-performance CNF-TN-based airborne particulate matter (PM) filters. First, single-layer hybrid cryogels with varying TN contents (0-5% w v) are assembled, and the design principles for multilayered filters are established based on a novel sequential pre-freezing and freeze-drying technique. As observed, the embedded TNs transformed the CNF network into a more homogeneous, isotropic, and firm structure, thus improving the structural integrity and thermal stability of the assembled cryogels while maintaining their ultrahigh porosity and low density.

Evaluation of a commercial histoplasma antigen detection enzyme immunoassays for the follow-up of histoplasmosis treatment in people living with HIV from Argentina.

Histoplasmosis poses a significant risk to HIV patients, particularly in regions with limited access to antiretroviral therapy. Antigen detection assays are crucial in these settings for timely diagnosis and treatment, which can reduce mortality. While commercial antigen detection kits have performed well in diagnosing histoplasmosis, their effectiveness in monitoring treatment remains unclear.

Exploring CTRP6: a biomarker and therapeutic target in metabolic diseases.

The rising prevalence of metabolic diseases is a significant global health concern. Beyond lifestyle management, targeting key molecules involved in metabolic regulation is essential. C1q/TNF-related protein 6 (CTRP6) is notably associated with glucose and lipid metabolism, with numerous studies highlighting its regulatory functions in metabolic diseases.

Efficacy and safety of ensifentrine, a novel phosphodiesterase 3 and 4 inhibitor, in chronic obstructive pulmonary disease: A systematic review and meta-analysis.

Background: We evaluated the efficacy and safety of Ensifentrine in COPD via a systematic review and meta-analysis of randomized controlled trials (RCTs).

Methods: We performed a detailed literature search on Medline (via PubMed), Scopus, Google Scholar, and Cochrane on the basis of pre-specified eligibility criteria. We used Review Manager to calculate pooled mean differences (MD) and 95% Confidence Interval (CI) using a random effects model.

Long-Term Follow-Up and Overall Survival in NRG258, a Randomized Phase III Trial of Chemoradiation Versus Chemotherapy for Locally Advanced Endometrial Carcinoma.

This randomized phase III trial aimed to determine whether treatment with cisplatin and volume-directed radiation followed by carboplatin and paclitaxel for four cycles (chemoradiotherapy [C-RT]) increased recurrence-free survival (RFS) and overall survival (OS) when compared with carboplatin and paclitaxel for six cycles (chemotherapy [CT]) in locally advanced endometrial cancer (UC). Previously reported results showed that C-RT did not improve RFS compared with CT. Here we report the final OS analysis.