Assist Technol
December 2024
School of Information Studies, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
The Memory Book approach to dementia care effectively fosters daily communication with individuals with dementia. With technological advancements, the traditional memory book intervention has evolved into digital forms. However, it remains unclear whether family caregivers (FCGs) perceive this transition as beneficial or not, especially when their loved ones with dementia demonstrate communicative deficits.
View Article and Find Full Text PDFBrain Commun
November 2024
Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge CB2 0SP, UK.
J Inorg Biochem
February 2025
Department of Chemistry and Biochemistry, Ohio University, Athens, OH 45701, USA. Electronic address:
Nitric oxide (NO) is an essential inorganic signaling molecule produced by constitutive NO synthase (cNOS) in the neurological system. Under pathological conditions, NO rapidly reacts with superoxide (O) to generate peroxynitrite (ONOO). Elevated ONOO concentrations induce nitroxidative stress, potentially contributing to numerous pathological processes as observed in neurodegenerative diseases including Alzheimer's disease (AD).
View Article and Find Full Text PDFMolecules
November 2024
Chemistry Department, Vanderbilt University, Nashville, TN 37235, USA.
The use of nicotinamide cofactors in cell-free biocatalytic systems is necessitated by the high specificity that these enzymes show for their natural redox mediators. Unfortunately, isolation and use of natural cofactors is costly, which suggests that enhancing their stability is key to enabling their use in industrial processes. This study details NAD and NADH stability in three buffer systems (sodium phosphate, HEPES, and Tris) at 19 °C and 25 °C and for up to 43 d.
View Article and Find Full Text PDFJ Clin Med
November 2024
Diabetes Institute, Ohio University Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.
J Bodyw Mov Ther
October 2024
Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, USA; Diabetes Institute, Ohio University, Athens, OH, USA; Institute to Advance Health Equity Science, Ohio University, Athens, OH, USA. Electronic address:
Unlabelled: Parents often point to bedtime as a source of frustration, yet early bedtimes and sufficient sleep are important for children's development, learning, and behavior.
Objectives: This pilot study aimed to assess the feasibility and preliminary effectiveness of a yoga-based bedtime routine in a sample of parent-child dyads from a rural community.
Methods: Using a waitlist control study design, children aged 2-5 years and their parent were randomized to either intervention (yoga) or control (bedtime story) groups.
J Midwifery Womens Health
December 2024
Department of Social Medicine, Ohio University Heritage College of Osteopathic Medicine and Global Health Initiative, College of Health Sciences and Professions, Dublin, Ohio.
J Child Adolesc Psychiatr Nurs
November 2024
Faculty of Health, Southern Cross University, Lismore, New South Wales, Australia.
Front Public Health
November 2024
Center for Research in Health in Latin America (CISeAL), Pontifical Catholic University of Ecuador, Quito, Ecuador.
Introduction: The importance of nurturing care for child development is well-established, and parents play a central role in providing this care. However, cultural values and traditions can influence child-rearing practices, and there are gaps in child welfare in Ecuador. Two research questions delve into caregivers' definitions of nurturing care for children aged 0-5 and its alignment with World Health Organization's concept.
View Article and Find Full Text PDFSchizophr Res
December 2024
Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O'Hara St, Pittsburgh, PA 15213, United States of America. Electronic address:
Cumulative research finds that exposure to childhood trauma, sleep dysfunction, and high stress levels are prevalent in youth diagnosed with and at-risk for psychotic disorders. However, few studies have investigated the association between nightly sleep and moment-to-moment stress in youth who are at familial high-risk (FHR) for psychotic disorders with varying levels of exposure to childhood trauma. The current study examined the day-to-day associations between trauma severity, nightly sleep duration, and next-day momentary stress in 19 FHR and 19 non-psychiatric youth (ages 13-19 years, 66 % girls).
View Article and Find Full Text PDFMusculoskelet Sci Pract
February 2025
Ohio Musculoskeletal and Neurological Institute (OMNI), Ohio University, Athens, OH, USA; Department of Physical Therapy, College of Health Sciences and Professions, Ohio University, Athens, OH, USA.
Background: The anterior cruciate ligament (ACL) is integral to maintaining knee joint stability but is susceptible to rupture during physical activity. Despite surgical restoration of passive or mechanical stability, patients struggle to regain strength and prior level of function. Recent efforts have focused on understanding how ACL-related changes in the nervous system contribute to deficits in sensorimotor control following injury and reconstruction.
View Article and Find Full Text PDFPublic Health Nutr
November 2024
Department of Psychology, Ohio University, Athens, OH, USA.
Objective: To evaluate the effectiveness of a radio campaign involving serial 10-minute drama episodes, 10-minute on air discussion of each episode by trained community health workers and 30-minute phone-ins from listeners in improving mothers' nutrition- and health-related attitudes (HNRAs) and children's minimum acceptable diet (MAD).
Design: A two-arm quasi-experimental trial with a pre-post design was used to quantify the effect of a radio campaign on nutrition before and immediately after the 6-month intervention. Difference-in-difference (DID) analysis was performed to assess the intervention's effect.
Phys Rev E
October 2024
Departamento de Física, CEDENNA, Universidad Técnica Federico Santa María, Av. España 1680, Valparaíso 2390123, Chile.
J Am Med Dir Assoc
January 2025
Department of Primary Care, OU-HCOM, Athens, OH, USA; Primary Care-Geriatrics Clinic, OhioHealth Physician Group Heritage College Primary Care, Athens, OH, USA. Electronic address:
AIP Adv
November 2024
Department of Chemistry and Biochemistry, Nanoscale and Quantum Phenomena Institute, Ohio University, Athens, Ohio 45701, USA.
Diffusive adsorption/association is a fundamental step in almost all chemical reactions in diluted solutions, such as organic synthesis, polymerization, self-assembly, biomolecular interactions, electrode dynamics, catalysis, chromatography, air and water environmental dynamics, and social and market dynamics. However, predicting the rate of such a reaction is challenging using the equations established over 100 years ago. Several orders of magnitude differences between the theoretical predictions and experimental measurements for various systems, from self-assembled monolayers to protein-protein aggregations, make such calculations meaningless in many situations.
View Article and Find Full Text PDFJ Electrocardiol
January 2025
Department of Biocybernetics and Biomedical Engineering, AGH University of Krakow, al. Mickiewicza 30, 30-059 Krakow, Poland.
The electrocardiogram (ECG) stands out as one of the most frequently used medical tests, playing a crucial role in the accurate diagnosis and treatment of patients. While ECG devices generate a huge amount of data, only a fraction of it holds valuable medical information. To deal with this problem, many compression algorithms and filters have been developed over the years.
View Article and Find Full Text PDFNat Commun
November 2024
Department of Biology, Washington University in St. Louis, St. Louis, MO, USA.
Ecological character displacement, whereby shifts in resource use in the presence of competing species leads to adaptive evolutionary divergence, is widely considered an important process in community assembly and adaptive radiation. However, most evidence for character displacement has been inferred from macro-scale geographic or phylogenetic patterns; direct tests of the underlying hypothesis of divergent natural selection driving character displacement in the wild are rare. Here, we document character displacement between two ecologically similar lizards (Anolis sagrei and A.
View Article and Find Full Text PDFBiodemography Soc Biol
November 2024
Pacific Health Research and Education Institute, Honolulu, HI, USA.
Obesity (Silver Spring)
December 2024
Department of Biomedical Sciences and Diabetes Institute, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA.
Objective: Apolipoprotein A4 (APOA4) is synthesized by the small intestine in response to dietary lipids. Chronic exposure to a high-fat diet (HFD) desensitizes lipid-induced APOA4 production and attenuates brown adipose tissue (BAT) thermogenesis. We hypothesized that exogenous APOA4 could increase BAT thermogenesis and energy expenditure in HFD-fed mice, resulting in decreased obesity and improved glucose tolerance.
View Article and Find Full Text PDFFront Med (Lausanne)
October 2024
Faculty of Chinese Medicine, Macau University of Science and Technology, Macau, China.
BMC Neurol
November 2024
Department of Medicine, Nazarbayev University School of Medicine, Kerey and Zhanibek, Street 5/1, Astana, 010000, Republic of Kazakhstan.
Background: Central Asia is known to face various ecological challenges that constitutes major risk factors for Parkinson's disease (PD). This study examines the burden of PD in Central Asia, a region where data on neurological disorders is notably sparse.
Methods: Building on the latest Global Burden of Disease Study (GBD 2021), this study investigates the Years of Life Lost (YLLs), Years Lived with Disability (YLDs), and Disability-Adjusted Life Years (DALYs) associated with PD in Central Asia and its countries from 1990 to 2021.
Geroscience
November 2024
David B. Kriser Dental Center, Department of Molecular Pathobiology, New York University College of Dentistry, 345 East 24Th Street, New York, NY, 10010-4086, USA.
Several mouse lines with congenital growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis disruption have shown improved health and extended lifespan. The current study investigated how inactivating this axis, specifically during aging, impacts the healthspan. We used a tamoxifen-inducible global GH receptor (GHR) knockout mouse model starting at 12 months and followed the mice until 24 months of age (iGHRKO mice).
View Article and Find Full Text PDFAging Ment Health
December 2024
Department of Psychology, Ohio University, Athens, OH, USA.
Objectives: Although anxiety and depression decrease across the lifespan, age-related anxieties increase in older adults, particularly worries about experiencing cognitive decline or dementia. Dementia Worry (DW) is characterized by ruminative concerns about developing or experiencing symptoms of dementia. DW is related to negative mental health outcomes in older adults and increases as a function of exposure to dementia in others.
View Article and Find Full Text PDFAlzheimers Res Ther
November 2024
Trinity College Institute of Neuroscience, School of Psychology, Trinity College Dublin, Dublin, Ireland.
Zhongguo Zhen Jiu
November 2024
Department of Specialty Medicine, Ohio University, Ohio 43055, USA.
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